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It was probably the French chemist Portes, who first reported in 1880 that the mucin in the vitreous body, which he named hyalomucine, behaved differently from other mucoids in cornea and cartilage. Fifty four years later Karl Meyer isolated a new polysaccharide from the vitreous, which he named hyaluronic acid. Today its official name is hyaluronan, and modern-day research on this polysaccharide continues to grow. Expertly written by leading scientists in the field, this book provides readers with a broad, yet detailed review of the chemistry of hyaluronan, and the role it plays in human biology and pathology. Twenty-seven chapters present a sequence leading from the chemistry and biochemistry of hyaluronan, followed by its role in various pathological conditions, to modified hylauronans as potential therapeutic agents and finally to the functional, structural and biological properties of hyaluronidases. Chemistry and Biology of Hyaluronan covers the many interesting facets of this fascinating molecule, and all chapters are intended to reach the wider research community. * Comprehensive look at the chemistry and biology of hyaluronans * sential to Chemists, Biochemists and Medical researchers * broad yet detailed review of this rapidly growing research area.

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The finding by Emil Fischer that glucose and fructose on treatment with phenylhydrazine gave the identical osazone led him to the elucidation of stereochemistry of carbohydrates. Since then, progress in the field of carbohydrates has been amazing with the unraveling their basic structure, biosynthesis, immunology, functions, and clinical uses, for pure carbohydrates and for protein-linked carbohydrates (glycoproteins and proteoglycans). The chapters in this book present a logical sequence leading from the chemistry and biochemistry of carbohydrates, followed by their role in various patho

Carbohydrates. --- Carbohydrates --- Carbohydrates in human nutrition. --- Metabolism --- Disorders. --- Nutrition --- Carbohydrate metabolism disorders --- Carbs (Carbohydrates) --- Biomolecules --- Organic compounds --- Glycomics

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The finding by Emil Fischer that glucose and fructose on treatment with phenylhydrazine gave the identical osazone led him to the elucidation of stereochemistry of carbohydrates. Since then, progress in the field of carbohydrates has been amazing with the unraveling their basic structure, biosynthesis, immunology, functions, and clinical uses, for pure carbohydrates and for protein-linked carbohydrates (glycoproteins and proteoglycans). The chapters in this book present a logical sequence leading from the chemistry and biochemistry of carbohydrates, followed by their role in various pathological conditions, to carbohydrates as potential therapeutic and diagnostic agents. This book offers a detailed panoramic review of the chemistry and biology of carbohydrates for chemists, biologists and health professionals. Each chapter is authored by contributors expert in the particular area of research.

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The Textbook of Pulmonary Vascular Disease combines basic scientific knowledge on the pulmonary circulatory system at levels of the molecule, cell, tissue, and organ with clinical diagnosis and treatment of pulmonary vascular diseases. State-of-the-art techniques and their potential applications in research, diagnosis, and treatment of pulmonary vascular diseases are also covered. Jason X.-J. Yuan, MD, PhD is Professor of Medicine, University of Illinois at Chicago, Chicago, IL Joe G.N. Garcia, MD is Earl Banes Professor of Medicine and Vice Chancellor for Research, University of Illinois at Chicago, Chicago, IL Charles A. Hales, MD is Professor of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA Stuart Rich, MD is Professor of Medicine, University of Chicago, Chicago, IL Stephen L. Archer, MD is Harold Hines Jr. Professor of Medicine and Chief of Cardiology, University of Chicago, Chicago, IL John B. West, MD, PhD, DSc is Distinguished Professor of Physiology and Medicine, University of California, San Diego, La Jolla, CA

Pathology of the circulatory system --- Orthopaedics. Traumatology. Plastic surgery --- spoedgevallen --- intensieve zorgen --- cardiologie --- Hypertension, Pulmonary. --- Pulmonary Circulation. --- Lungs --- Poumons --- Blood-vessels. --- Diseases --- Vaisseaux sanguins --- Maladies --- EPUB-LIV-FT LIVMEDEC SPRINGER-B --- Blood-vessels --- Diseases.