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Physiology of the respiratory system

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In the general assembly of International Society for Arterial Chemoreception (ISAC) at the XIV Meeting of ISAC in Philadelphia (June, 1999) the membership decided that tentatively the XVI Meeting of the Society will be held in Japan. At the conclusion of the XV ISAC Meeting held in Lyon (France) in November 2002, Hisatake Kondo took of the torch as president of ISAC, and took the responsibility of organizing the XVI Meeting of the Society in Sendai (Japan). This book contains the Proceedings of XVI ISAC Meeting held at Miyagi Zao Royal Hotel in the suburb of Sendai, Japan, from May 9 to 12, 2005. Hisatake Kondo counted with a group of colleague co-organizers from different Japanese institutions, including Yoshiaki Hayashida from Osaka, Katsuaki Yoshizaki from Akita, Yoko Kameda from Kanagawa, Tatsumi Kusakabe from Tokyo, Yuji Owada from Sendai and Hiroyuki Sakagami also from Sendai. The Scientific Committee was formed by some ISAC members from abroad. Professors Helmut Acker (Germany), Carlos Eyzaguirre (USA), Salvatore Fidone (USA), Robert Fitzgerald (USA), Constancio Gonzalez (Spain), Sukhamay Lahiri (USA), Jean Marc Pequignot (France) and Patricio Zapata (Chile) helped with their advice to take decisions on specific aspects of the scientific programme. Recommendations given by Dr. Prem Kumar (UK), acting treasurer of ISAC, were invaluable to solve last minute contingencies.

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The carotid body arterial chemoreceptors constitute unique sensory receptors capable of rapidly monitoring the levels of arterial blood oxygen and carbon dioxide. This book presents a review of the physiology of the carotid body chemoreceptors. It is suitable for those in the fields of hypoxic pulmonary vasoconstriction and pulmonary hypertension.

Carotid body. --- Chemoreceptors. --- Human physiology. --- Ion channels. --- Medicine. --- Neurosciences. --- Oxygen. --- Pneumology. --- Respiration -- Regulation. --- Respiration. --- Chemoreceptors --- Respiration --- Metabolic Phenomena --- Membrane Glycoproteins --- Gases --- Biological Science Disciplines --- Paraganglia, Nonchromaffin --- Publication Formats --- Chalcogens --- Membrane Transport Proteins --- Sensory Receptor Cells --- Inorganic Chemicals --- Membrane Proteins --- Neurons, Afferent --- Elements --- Natural Science Disciplines --- Publication Characteristics --- Peripheral Nervous System --- Phenomena and Processes --- Carrier Proteins --- Proteins --- Chemicals and Drugs --- Nervous System --- Neurons --- Disciplines and Occupations --- Amino Acids, Peptides, and Proteins --- Cells --- Anatomy --- Chemoreceptor Cells --- Ion Channels --- Carotid Body --- Oxygen --- Physiology --- Metabolism --- Congresses --- Human Anatomy & Physiology --- Health & Biological Sciences --- Neuroscience --- Regulation --- Regulation. --- Regulation of respiration --- Respiratory organs --- Environmental health. --- Biomedicine. --- Biomedicine general. --- Human Physiology. --- Pneumology/Respiratory System. --- Environmental Health. --- Diseases. --- Environmental quality --- Health --- Health ecology --- Public health --- Environmental engineering --- Health risk assessment --- Respiratory diseases --- Neural sciences --- Neurological sciences --- Medical sciences --- Nervous system --- Human biology --- Human body --- Clinical sciences --- Medical profession --- Life sciences --- Pathology --- Physicians --- Health aspects --- Environmental aspects --- Biological control systems --- Carotid body --- Sensory receptors --- Chemical senses --- Environmental Medicine. --- Respiratory organs—Diseases. --- Biomedicine, general. --- Health Workforce

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Arterial chemoreceptors are unique structures which continuously monitor changes in arterial blood oxygen, carbon dioxide, glucose, and acid.  Alterations in these gases are almost instantaneously sensed by arterial chemoreceptors and relayed into a physiological response which restores blood homeostasis.  Arterial Chemoreception contains updated material regarding the physiology of the primary arterial chemoreceptor; the carotid body.  Moreover, this book also explores tantalizing evidence regarding the contribution of the aortic bodies, chromaffin cells, lung neuroepithelial bodies, and brainstem areas involved in monitoring changes in blood gases.  Furthermore this collection includes data showing the critical importance of these chemoreceptors in the pathophysiology of human disease and possible therapeutic treatments. This book is a required text for any researcher in the field of arterial chemoreception for years to come.  It is also a critical text for physicians searching for bench-to-bedside treatments for heart failure, sleep apnea, and pulmonary hypertension.