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Piperidine, one of the simplest heterocyclic systems, is found in nature as part of several alkaloid compounds. Both natural and especially unnatural piperidine derivatives present interesting pharmacological properties. From a structural viewpoint, the conformation of piperidine has been the subject of one of the fiercest controversies in structural organic chemistry in the last few years. As a result of the combined use of several spectroscopic techniques, the conformational behavior of most types of piperidine-related compounds has been clarified. Some piperidine derivatives, namely, N-acyl

Piperidine. --- Hexahydropyridine --- Pentamethyleneamine --- Pentamethyleneimine --- Heterocyclic compounds --- Piperidine

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Drugs --- Protein-protein interactions --- Proteins --- High throughput screening (Drug development) --- Drug Discovery --- Enzyme Inhibitors --- Protein Binding. --- Surface Properties --- Design. --- Inhibitors. --- metabolism. --- methods. --- pharmacology.