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"Biomolecular Therapeutics for Human Cancer is the only resource to focus on biomolecular approaches to cancer therapy. Its presentation of the latest research in cancer biology reflects the interdisciplinary nature of the field and aims to facilitate collaboration between the basic, translational, and clinical sciences"--Provided by publisher.
Neoplasms --- DNA Methylation. --- Drug Design. --- Epigenesis, Genetic. --- Histones --- Cancer --- Epigenesis. --- DNA --- Epigénèse --- ADN --- genetics. --- therapy. --- metabolism. --- Genetic aspects. --- Treatment. --- Methylation. --- Aspect génétique --- Traitement --- Méthylation --- Metabolism. --- Genetics. --- Therapy. --- Dna methylation. --- Dna --- Drug design. --- Epigenesis, genetic. --- Epigénèse --- Aspect génétique --- Méthylation
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Breast Cancer is the most common tumor in women and it is the second leading cause of cancer deaths worldwide. Due to breakthroughs in gene profiling, the knowledge of the pathophysiology of the mammary gland had greatly increased over the last decade. In Breast Cancer in the Post Genomic Era, Antonio Giordano, Nicola Normanno, and a panel of international authorities in their field provide a comprehensive approach to the biology, diagnosis, prevention, and treatment of human breast carcinoma. The book provides a comprehensive approach to breast cancer, describing the use of gene profiling techniques to distinguish specific features of individual carcinomas, as well as emerging novel therapeutic approaches to treatment. Additional chapters cover the use of transgenic mice to model human breast cancer and the role of the EGF-CFC family in mammary gland development and neoplasia. Breast Cancer in the Post Genomic-Era succeeds in looking at breast cancer pathogenesis, diagnosis, and treatment under a more comprehensive light, and is a valuable resource for any Radiation or Surgical Oncologist, Cancer Biologist or Pathologist.
Breast -- Cancer -- Diagnosis. --- Breast -- Cancer -- Etiology. --- Breast -- Cancer -- Genetic aspects. --- Breast -- Cancer -- Treatment. --- Breast --- Breast Diseases --- Neoplasms by Site --- Neoplasms --- Skin Diseases --- Skin and Connective Tissue Diseases --- Diseases --- Breast Neoplasms --- Medicine --- Health & Biological Sciences --- Oncology --- Cancer --- Etiology --- Diagnosis --- Treatment --- Genetic aspects --- Diagnosis. --- Etiology. --- Genetic aspects. --- Treatment. --- Medicine. --- Oncology. --- Pathology. --- Surgical oncology. --- Medicine & Public Health. --- Surgical Oncology. --- Oncology . --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Tumors --- Excision
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Facilitating the collaboration between the basic, translational, and clinical sciences, this book provides an overview of the genetic and epigenetic mechanisms underlying the formation and progression of gynecological cancers. Gynecological Cancers: Genetic and Epigenetic Targets and Drug Development gathers all of the molecular and cellular aspects of gynecological cancer together within one volume, providing detailed and up-to-date information on the etiology, diagnosis, and treatment of gynecological cancers. Gynecological Cancers: Genetic and Epigenetic Targets and Drug Development also discusses the racial and ethnic disparities in the treatment of gynecological cancers through cost effective modalities like single visit screening and diagnosis, well women clinics, and mobile clinics. Written and edited by leaders in the field, this volume within the Current Clinical Oncology series is an indispensable resource for today’s practicing oncologist.
Medicine. --- Gynecology. --- Oncology. --- Medicine & Public Health. --- Generative organs, Female --- Cancer --- Genetic aspects. --- Treatment. --- Oncology . --- Gynaecology --- Medicine --- Tumors --- Diseases --- Gynecology .
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Complex physiopathological relationships have been proven to exist between two of the body’s most vital organs; the brain and the heart. In Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems Antonio Giordano, Umberto Galderisi and a panel of the most respected authorities in their field offer an in-depth analysis of the differentiation process in two systems that have profound relationships with one another. The text looks at several aspects of the cardiovascular and nervous systems from a new point of view, describing the differences and similarities in their differentiation pathways with an emphasis on the role of cell cycle regulation and cell differentiation. Topics discussed include neurogenesis in the central nervous system, neural stem cells, and the basic-helix-loop-helix transcription factors in neural differentiation. Ground-breaking and authoritative, Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems is a must have for all researchers in cardiovascular medicine and neuroscience and will prompt the scientific community to perceive cell cycle regulation and differentiation under a novel and more comprehensive light.
Cell cycle -- Regulation. --- Central nervous system -- Differentiation. --- Heart -- Differentiation. --- Cell cycle --- Heart --- Central nervous system --- Cell Physiological Processes --- Circulatory and Respiratory Physiological Phenomena --- Musculoskeletal and Neural Physiological Phenomena --- Biological Science Disciplines --- Nervous System Physiological Phenomena --- Cell Differentiation --- Cardiovascular Physiological Phenomena --- Physiology --- Cell Cycle --- Cell Physiological Phenomena --- Natural Science Disciplines --- Phenomena and Processes --- Disciplines and Occupations --- Human Anatomy & Physiology --- Medicine --- Biology --- Anatomy --- Cytology --- Cardiovascular Diseases --- Health & Biological Sciences --- Regulation --- Differentiation --- Regulation. --- Differentiation. --- Nervous system, Central --- Regulation of cell cycles --- Medicine. --- Neurosciences. --- Human anatomy. --- Cardiology. --- Neurology. --- Medicine & Public Health. --- Anatomy. --- Nervous system --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Neuropsychiatry --- Anatomy, Human --- Human biology --- Human body --- Internal medicine --- Diseases --- Neurology .
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This book provides a comprehensive, state-of-the art review and serves as an overview of the different aspects of gastric cancer. The first section aims to clarify the main aspects of tumorigenesis, such as the role of inflammation linked to the presence of H. Pylori infection, and the genetic and epigenetic mechanisms so far known. Secondly, an exhaustive overview of the diagnosis of gastric cancer from a clinical/endoscopic and pathologic perspective will be illustrated. The second section includes the pathological and clinical features and contains information regarding the most recent tissue and serological biomarkers in these neoplasms. The three successive sections are intended to provide the “state of art” of multimodal treatment approaches to gastric cancer, i.e. standard and novel surgical aspects, common and innovative chemo and radio protocols and modern targeted therapies. Novel molecular classifications are under consideration to improve diagnostic and prognostic definitions and to prospect future treatments based on the use of immunotherapies and innovative molecules such as non-coding RNA and nanoparticles. Gastric Cancer in the Precision Medicine Era serves as a useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It provides a concise yet comprehensive summary of the current status of the field that helps guide patient management and stimulates investigative efforts. All chapters are written by experts in their fields and includes the most up to date scientific and clinical information.
Stomach --- Cancer --- Diagnosis. --- Pathology. --- Gastroenterology. --- Surgery. --- Oncology . --- General Surgery. --- Oncology. --- Tumors --- Surgery, Primitive --- Medicine --- Internal medicine --- Digestive organs --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine, Preventive --- Gastroenterology .
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Pleura --- Diseases. --- Pleural Diseases. --- Disease, Pleural --- Diseases, Pleural --- Pleural Disease
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