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This volume explores the mechanisms of resistance to targeted therapeutics. The focus is on the cancer cell signaling network, although other mechanisms of resistance including target mutation, and new areas of study such as cancer stem cells are included.  Targeted Therapies: Mechanisms of Resistance highlights examples of changes in the signaling network in response to inhibition of a signaling event and underscores the importance in having a mechanistic understanding of the signaling network in cancer for developing effective targeted cancer therapies. Moreover, cutting edge tools to analyze the cell signaling network will be discussed. This includes the leading edge of techniques as well as computational biology and systems theory. This volume provides the reader with both an overview as well as a detailed perspective on the mechanisms of resistance to targeted therapeutics and will be of great value to the oncologist, the physician-scientist treating patients and the translational scientist working on any aspect of targeted therapeutics.

Antineoplastic Agents -- therapeutic use. --- Cancer -- Chemotherapy. --- Neoplasms -- drug therapy. --- Tumoren. --- Cancer --- Drug targeting --- Drug Resistance --- Therapeutic Uses --- Diseases --- Therapeutics --- Pharmacological Phenomena --- Pharmacologic Actions --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Chemical Actions and Uses --- Physiological Phenomena --- Chemicals and Drugs --- Phenomena and Processes --- Drug Therapy --- Drug Resistance, Neoplasm --- Molecular Targeted Therapy --- Antineoplastic Agents --- Neoplasms --- Medicine --- Health & Biological Sciences --- Oncology --- Treatment --- Public health. --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Sanitary affairs --- Social hygiene --- Medicine. --- Cancer research. --- Molecular biology. --- Oncology. --- Medicine & Public Health. --- Molecular Medicine. --- Cancer Research. --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Oncology  . --- Tumors --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Health Workforce --- Cancer research --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This volume explores the mechanisms of resistance to targeted therapeutics. The focus is on the cancer cell signaling network, although other mechanisms of resistance including target mutation, and new areas of study such as cancer stem cells are included.  Targeted Therapies: Mechanisms of Resistance highlights examples of changes in the signaling network in response to inhibition of a signaling event and underscores the importance in having a mechanistic understanding of the signaling network in cancer for developing effective targeted cancer therapies. Moreover, cutting edge tools to analyze the cell signaling network will be discussed. This includes the leading edge of techniques as well as computational biology and systems theory. This volume provides the reader with both an overview as well as a detailed perspective on the mechanisms of resistance to targeted therapeutics and will be of great value to the oncologist, the physician-scientist treating patients and the translational scientist working on any aspect of targeted therapeutics.

Molecular biology --- Oncology. Neoplasms --- oncologie --- moleculaire biologie --- Neoplasms --- Antineoplastic Agents --- Drug Resistance, Neoplasm. --- Molecular Targeted Therapy. --- Cancer --- Drug targeting. --- Médicaments --- drug therapy. --- therapeutic use. --- Treatment. --- Traitement --- Ciblage --- EPUB-LIV-FT LIVMEDEC SPRINGER-B