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Chromatography and Modification of Nucleosides is a four-volume work which provides state-of-the-art chromatography and analytical methods for use in a wide spectrum of nucleic acid modification research. The focus of Part A, is the presentation of advanced methods for modification research on tRNAs, mRNAs, mtRNAs, rRNAs and DNAs. HPLC-UV, GC-MS, NMR, FT-IR and affinity chromatography approaches to nucleic acid modification studies are presented, as are nucleoside, oligonucleotide and nucleic acid isolation techniques. Part B has as its central theme the modified nucleosides of tRNA and the current analytical means for studying tRNA modifications. Modified nucleoside synthesis, function, structural conformation, biological regulation, and occurrence of modification in a wide range of tRNAs are presented, as is a chapter on DNA modification and a chapter on solid phase immunoassay for determining a particular modification. Part C provides the reader with a comprehensive treatment of modified nucleosides as biochemical signals of neoplasia and normal metabolism. The final volume, Part D, will present structural characterization of unknown nucleosides as well as extensive biochemical, chemical and physical properties of RNA and DNA nucleosides, as a "database" for researchers in the field. Chromatographic methodology will be described for analysis of total modification of tRNAs and DNAs. The chapters are written by leading scientists in their respective fields and present an up-to-date review on the roles of modified nucleosides in nucleic acids which will be extremely useful for workers in chromatography, molecular biology, genetics, biochemistry, biotechnology and the pharmaceutical industry.

Analytical biochemistry

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Modified Nucleosides in Cancer and Normal Metabolism - Methods and Applications

Analytical biochemistry --- Nucleosides --- Nucléosides --- Metabolism --- Derivatives --- Synthesis --- Métabolisme --- Dérivés --- Synthèse --- Synthesis. --- Metabolism. --- 577.113.3 --- 543.54 --- 543.54 Capillary analysis. Adsorption analysis. Stalagmometry. Chromatography. Electrophoresis --- Capillary analysis. Adsorption analysis. Stalagmometry. Chromatography. Electrophoresis --- 577.113.3 Nucleosides, nucleotides and nitrogen bases.Nucleotide composition of nucleic acids. --- Nucleosides, nucleotides and nitrogen bases.Nucleotide composition of nucleic acids. --- -Nucleosides --- -Nucleotides --- -Synthesis --- Nucleosides. --- Nucleotides --- -Derivatives

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Chromatography - A Century of Discovery 1900-2000 represents the combined thinking and contributions of many chromatographers. It includes several in-depth feature chapters covering the Beginnings of Chromatography, which highlights M.S. Tswett, the inventor of chromatography, and several other early pioneers. Included are the contributions of several Nobel Laureates,and 125 Chromatography Award Winners and contributors, an extensive bibliography of publications on the History of the Evolution of Chromatography; a presentation of Major International Symposia supporting chromatography and as a

Chromatographic analysis --- History --- Analysis, Chromatographic --- Chromatography --- Analytical chemistry --- Phase partition --- Chromatographic analysis - History - 20th century

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