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This book provides a snapshot of the state-of-the art in the study of mammalian cell nuclear architecture, and features a diverse range of chapters written by top researchers. A key aspect is an emphasis on precise and repeatable quantitative analysis and simulation in addition to the more familiar biological perspective. The fusion of such material frames the future of the discipline. Quantitative contributions stress reproducible and robust 3D analysis, using a variety of tools ranging from point pattern analysis to shape registration methods. Biological insights include the role of nuclear subdomains in cancer, nuclear molecular motors, and a holistic view of gene transcription.

Cell nuclei. --- Mammals -- Cytology. --- Microscopy. --- Cell nuclei --- Cytology --- Biology --- Health & Biological Sciences --- Molecular biology. --- Cytology. --- Cell biology --- Cellular biology --- Molecular biochemistry --- Molecular biophysics --- Cell nucleus --- Nucleus (Cells) --- Medicine. --- Medical genetics. --- Cell biology. --- Cell physiology. --- Biomedicine. --- Biomedicine general. --- Cell Biology. --- Gene Function. --- Cell Physiology. --- Cells --- Cytologists --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Cell organelles --- Cell function --- Physiology --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Physicians --- Genetic aspects --- Biomedicine, general. --- Health Workforce

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book provides a snapshot of the state-of-the art in the study of mammalian cell nuclear architecture, and features a diverse range of chapters written by top researchers. A key aspect is an emphasis on precise and repeatable quantitative analysis and simulation in addition to the more familiar biological perspective. The fusion of such material frames the future of the discipline. Quantitative contributions stress reproducible and robust 3D analysis, using a variety of tools ranging from point pattern analysis to shape registration methods. Biological insights include the role of nuclear subdomains in cancer, nuclear molecular motors, and a holistic view of gene transcription.

Histology. Cytology --- Human biochemistry --- medische biochemie --- biochemie --- cytologie --- histologie