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This new volume in the series Emerging Infectious Diseases of the 21st Century is a novel book on the role of microbes in the pathogenesis of common and disabling non-infectious diseases. New insights have emerged over the past several years suggesting that our commensal microflora of the gut is extremely important in regulating physiological and immune functions of the body. Covered are the perturbations of the normal composition of our endogenous microbiota, influenced by diet and genetic predispositions, as well as the mechanisms to produce common disorders such as obesity, diabetes, irritable bowel syndrome, colon cancer, and atherosclerotic vascular diseases. Also explored is the evidence suggesting that predisposition to increasingly common afflictions such as asthma and multiple sclerosis is influenced, in combination with our genetic composition, by early life exposure to environmental microbes and the time of onset of common viral infections. Chapters provide the most recent information on these disorders with regards to epidemiology, current concepts on pathogenesis and mechanisms of their biology, recent research and data on the role of microbes, analysis of their validity, and conclusive remarks and areas for future research.  The Role of Microbes in Common Non-Infectious Diseases is an excellent resource for both physicians and investigators from a broad range of disciplines that will help to stimulate new concepts of disease pathogenesis, and lead to the unraveling of their mechanisms of diseases and to novel treatments. About the Author Ignatius [Bill] Fong is a Professor of Medicine at the University of Toronto and he is an author/ editor of 8 previously published books on Infectious Diseases. His research interests include topics in clinical infectious disease, HIV infection, and microbial-induced or -associated atherosclerosis.

Pathogenic microorganisms. --- Disease-causing microorganisms --- Micro-organisms, Pathogenic --- Pathogens --- Microorganisms --- Medical microbiology --- Virulence (Microbiology) --- Microbiology. --- Emerging infectious diseases. --- Immunology. --- Medical Microbiology. --- Infectious Diseases. --- Immunobiology --- Life sciences --- Serology --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Microbial biology --- Biology --- Medical microbiology. --- Infectious diseases.

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Despite the fact that most physicians will encounter medical litigation at some point in their careers, they have few resources for navigating through legal issues within the body of medical literature. With this in mind, this volume provides guidance to physicians and researchers.  As the latest in the Emerging Infectious Diseases of the 21st Century series, it gives case scenarios in the format of problem-solving challenges faced by physicians in various practices and subspecialties. It covers topics including issues in the surgical and neurosurgical disciplines, obstetrics and gynecological infections, skin/soft tissue conditions, fevers, and complications related to HIV. It also gives information medical liability laws around the world. Rather than encourage defensive medical practice, this book provides information on administering better care and being honest and fair with patients when addressing inevitable mistakes. It is a must for all practicing physicians.

Communicable diseases. --- Medicine -- Practice. --- Public health laws. --- Communicable diseases --- Public health laws --- Medicine --- Jurisprudence --- Communicable Diseases --- Social Control, Formal --- Infection --- Sociology --- Bacterial Infections and Mycoses --- Health Care Economics and Organizations --- Social Sciences --- Health Care --- Diseases --- Anthropology, Education, Sociology and Social Phenomena --- Malpractice --- Communicable Diseases, Emerging --- Health & Biological Sciences --- Infectious Diseases --- Practice --- Medical laws and legislation --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Medicine. --- Infectious diseases. --- Life sciences. --- Medical laws and legislation. --- Medicine & Public Health. --- Infectious Diseases. --- Life Sciences, general. --- Medical Law. --- Epidemics --- Emerging infectious diseases. --- Public health --- Biosciences --- Sciences, Life --- Science --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Law and legislation --- Law, Medical --- Medical personnel --- Medical registration and examination --- Physicians --- Surgeons --- Medical policy --- Medical jurisprudence --- Legal status, laws, etc.

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The book begins with a review of zoonotic pandemics of the past: the “Black Death” or bubonic plague of the Middle Ages, the Spanish Influenza pandemic (derived from avian influenza) of the early 20th century, to the more modern pandemic of AIDS/HIV infection, which originated in Africa from primates. However, the majority of chapters focus on more recent zoonoses, which have been recognized since the late 20th century to the present: SARS and MERS coronaviruses New avian influenza viruses The tick-borne Henan fever virus from China The tick-borne Heartland virus from the United States Recently recognized bacterial pathogens, such as Streptococcus suis from pigs. In addition, reemergence of established zoonoses that have expanded their niche are reviewed, such as the spread of Zika virus and Chikungunya virus to the Western Hemisphere, and the emergence and spread of Ebola virus infection in Africa. A chapter is also devoted to an overview of the mechanisms and various types of animals involved in the transmission of diseases to humans, and the potential means of control and prevention. Many endemic and sporadic diseases are still transmitted by animals, through either direct or indirect contact, and zoonoses are estimated to account for about 75% of all new and emerging infectious diseases. It is predicted by public health experts that the next major pandemic of infectious disease will be of animal origin, making Emerging Zoonoses: A Worldwide Perspective a crucial resource to all health care specialists by providing them with much needed information on these zoonotic diseases.

Animals as carriers of disease. --- Emerging infectious diseases. --- Communicable diseases in animals. --- Epizootic diseases --- Microbial diseases in animals --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Carriers of disease --- Disease vectors --- Vectors of disease --- Medicine. --- Medical microbiology. --- Virology. --- Infectious diseases. --- Medicine & Public Health. --- Infectious Diseases. --- Medical Microbiology. --- Animals --- Veterinary epidemiology --- Veterinary microbiology --- Communicable diseases --- Zoology, Medical --- Zoonoses --- Diseases --- Transmission --- Microbiology. --- Medical virology. --- Medical microbiology --- Virology --- Virus diseases --- Microbial biology --- Biology --- Microorganisms --- Microbiology

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Medical law --- Biology --- Infectious diseases. Communicable diseases --- biologie --- besmettelijke ziekten --- patiëntenrechten --- gezondheidsrecht