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The book comprehensively discusses the mechanisms of pathogenesis and drug resistance; current diagnostics landscape of four key human pathogens; bacterial, fungal, protozoans and viral which are the causes of major infectious diseases. It also assesses the emerging technologies for the detection and quantification of these pathogens. Further, it discusses the novel opportunities to fight against these infectious diseases and to identify pertinent drug targets with novel methodologies. It also reviews the current and future insights into the control, elimination, and eradication of these infectious diseases. Importantly, the book discusses the epidemiological characteristics and various challenges in combating Ebola and Influenza diseases. Finally, the book highlights the growing role of nanotechnology and bioinformatics resources for combating the infectious diseases. In summary, the book provides the mechanistic insight of the pathogenicity, drug-resistance, therapeutic strategies and identification of the novel drug targets of Mycobacterium tuberculosis, Plasmodium, Candida, Hepatitis C and emerging viral infections.

Parasitology. --- Infectious diseases. --- Drug resistance. --- Bioinformatics. --- Virology. --- Infectious Diseases. --- Drug Resistance. --- Microbiology --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Resistance to drugs --- Pharmacology --- Data processing --- Drug resistance in microorganisms. --- Communicable Diseases. --- Antimalarials. --- Antibiotic resistance in microorganisms --- Antibiotics resistance in microorganisms --- Bacterial resistance to antibiotics --- Drug resistance in micro-organisms --- Microbial drug resistance --- Resistance to drugs in microorganisms --- Microorganisms --- Anti-Malarials --- Antimalarial Agents --- Antimalarial Drugs --- Agents, Antimalarial --- Anti Malarials --- Drugs, Antimalarial --- Malaria --- Plasmodium --- Antirheumatic Agents --- Infectious Diseases --- Communicable Disease --- Disease, Communicable --- Disease, Infectious --- Diseases, Communicable --- Diseases, Infectious --- Infectious Disease --- Disease Outbreaks --- Disease Transmission, Infectious --- Resistance, Drug --- Pharmacogenetics --- Effect of drugs on --- Anti-Malarial --- Antimalarial --- Antimalarial Agent --- Antimalarial Drug --- Agent, Antimalarial --- Anti Malarial --- Drug, Antimalarial --- Resistència als medicaments --- Patologia --- Patologia humana --- Medicina --- Bacteriologia --- Càlculs --- Degeneració (Patologia) --- Diagnòstic de laboratori --- Estenosi --- Etiologia --- Genètica mèdica --- Glucòlisi --- Hipertròfia --- Histopatologia --- Hèrnia --- Immunopatologia --- Inflamació --- Insuficiència sistèmica --- Malformacions --- Metàstasi --- Paleopatologia --- Patologia cel·lular --- Patologia veterinària --- Teratologia --- Tumors --- Xoc --- Anatomia patològica --- Diagnòstic --- Farmacoresistència --- Farmacologia --- Resistència a la insulina --- Efecte dels medicaments sobre els microorganismes

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This book examines applications of multi-omics approaches for understanding disease etiology, pathogenesis, host-pathogen interactions. It also analyzes the genetics, immunological and metabolic mechanisms underlying the infections. The book also explores genomics, transcriptomics, translational-omics, and metabolomics approaches to understand the pathogenesis and identify potential drug targets. It reviews the role of epigenetic reprogramming in shaping the host-pathogen interactions and presents bioinformatics application in the identification of drug targets. Further, it examines the potential applications of RNA sequencing and non-coding RNA profiling to identify the pathogenesis. Lastly, it offers the current challenges, technological advances, and prospects of using multi-omics technologies in infectious biology.

General parasitology --- Medical microbiology, virology, parasitology --- medische microbiologie --- parasitologie --- virologie

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General parasitology --- Medical microbiology, virology, parasitology --- medische microbiologie --- parasitologie --- virologie