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This book reveals glimpses of how the quantum physics of atoms and molecules influences, and even controls, the way our cells function and how we and our fellow animals interact with our environment. Simply put, how birds fly and why grass grows.Certainly, biochemistry and molecular biology are the foundations for the biology of living cells, but there is more-quantum coherence and entanglement influencing the functioning of proteins and enzymes, and strictly speaking, without the quantum phenomena we wouldn't even be here. In the end, however, this book is based on the solid ground of science, presenting the many fascinating phenomena of how quantum physics makes life possible without any unwarranted mystification.
Quantum theory. --- Quantum biochemistry. --- Théorie quantique. --- Biochimie quantique.
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Leading scientists argue for a new paradigm for cancer research, proposing a complex systems view of cancer supported by empirical evidence.Current consensus in cancer research explains cancer as a disease caused by specific mutations in certain genes. Thanks to dramatic advances in genome sequencing, never before have we known so much about the individual cancer cell-and yet it is still unclear how to use this knowledge for treatment success. In this volume, leading researchers argue for a new theory framework for understanding and treating cancer. The contributors propose a complex systems view of cancer, presenting conceptual building blocks for a new research paradigm supported by empirical evidence.The contributors first discuss the new research framework in terms of theoretical foundations and then take up the relevance of a systems approach, reviewing such topics as nonlinearity, recurrence after treatment, the cellular attractor concept, network theory, and noncoding DNA-the "dark matter" of our genome. They address the temporality of cancer progression, drawing on evolutionary theory and clinical experience. Finally, they cover the dominant role of the tissue microenvironment in cancer, analyzing topics including altered metabolic pathways, the disease-defining influence on metastasis, and the interconnectedness of different environmental niches across levels of organization.
Cancer --- Neoplasms --- Cancer. --- Genetic aspects. --- genetics --- therapy --- Aspect génétique --- Thérapeutique. --- Cancer genetics --- Cancer genes --- genetics. --- therapy. --- Treatment. --- Cancer therapy --- Cancer treatment --- Therapy --- Aspect génétique --- Thérapeutique.
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