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Case studies of existing human tissue repositories : "best practices" for a biospecimen resource for the genomic and proteomic era
Authors: ---
ISBN: 1283597268 9786613909718 0833035932 0833035274 9780833035936 9780833035271 9781283597265 6613909718 Year: 2003 Publisher: Santa Monica, CA : RAND,

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Abstract

Case studies of twelve existing human biospecimen repositories performed to evaluate their utility for genomics- and proteomics-based cancer research and to identify ?best practices? in collection, processing, annotation, storage, privacy, ethical concerns, informed consent, business plans, operations, intellectual property rights, public relations, marketing, and education that would be useful in designing a national biospecimen network.

Keywords

Cadaver homografts--Case studies. --- Organizational Case Studies--United States. --- Preservation of organs, tissues, etc.--Case studies. --- Tissue banks--Case studies. --- Tissue Banks--standards--United States. --- Tissue Preservation--methods--United States. --- Health Care Evaluation Mechanisms --- Histocytological Preparation Techniques --- Preservation, Biological --- Health Services Research --- Biological Specimen Banks --- Quality of Health Care --- Investigative Techniques --- Cytological Techniques --- Specimen Handling --- Health Planning --- Histological Techniques --- Health Facilities --- Laboratory Techniques and Procedures --- Health Care Economics and Organizations --- Clinical Laboratory Techniques --- Health Care Facilities, Manpower, and Services --- Health Care Quality, Access, and Evaluation --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Health Care --- Diagnosis --- Tissue Preservation --- Tissue Banks --- Organizational Case Studies --- Surgery & Anesthesiology --- Health & Biological Sciences --- Transplantation of Organs & Tissues --- Tissue banks --- Preservation of organs, tissues, etc. --- Cadaver homografts --- Post-mortem homografts --- Postmortem homografts --- Organ preservation (Anatomy) --- Organs (Anatomy) --- Banks, Organ --- Banks, Tissue --- Banks, Transplant --- Organ banks --- Transplant banks --- Preservation --- Homografts --- Non-heart-beating organ donation --- Transplantation of organs, tissues, etc. --- Biobanks --- Health facilities --- Procurement of organs, tissues, etc.


Book
Vital Assets : Federal Investment in Research and Development at the Nation's Universities and Colleges
Authors: --- --- ---
ISBN: 1598754696 Year: 2004 Publisher: Santa Monica : RAND Corporation,

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Abstract

The federal government's investment in research and development (R&D) at the nation's universities-which is pivotal to the U.S. innovation system-has grown considerably. This report assesses that investment and presents a detailed analysis of the federal funds received for the conduct of R&D by state and by individual universities and colleges.


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The National Bioethics Advisory Commission : Contributing to Public Policy
Authors: ---
ISBN: 1598752677 Year: 2003 Publisher: Santa Monica : RAND Corporation,

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Abstract

This study assesses the US National Bioethics Advisory Commission's contribution to policymaking by tracking the response to its recommendations, on issues such as human cloning, from the President, Congress, government, societies and foundations, other countries and international groups.


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Monitoring for fine particulate matter
Authors: --- --- ---
Year: 1998 Publisher: Santa Monica, CA : RAND Corporation,

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Abstract

Particulate matter (PM)--dust, dirt, smoke, soot, and liquid droplets--comes from a variety of sources and is a mixture of many pollutants made up of several different chemical species. Recent evidence about health effects and the fundamental physical and chemical differences between fine and coarse PM prompted the EPA to set new standards. Monitoring to determine whether an area has met these standards requires a comprehensive approach that combines analytical techniques to assess mass and chemical composition with an integrated network of ambient and source PM monitors. However, chemical analysis of PM is costly and difficult, and existing technologies are not capable of continuous sampling and monitoring for chemical composition. Therefore, the next generation of PM monitors should be multifunctional instruments capable of continuous, real-time monitoring of both PM mass and chemical composition. In addition, they will need to address several barriers to their use, including cost, complicated calibration and verification systems, and cumbersome installation and maintenance procedures.


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Understanding and reducing off-duty vehicle crashes among military personnel
Authors: --- --- ---
Year: 2010 Publisher: Santa Monica, CA : RAND Corporation,

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The authors review traffic safety in the United States, with specific reference to military personnel, focusing on safety interventions and attempts to change driver behavior and decisions. Overall, driving has become safer over the last 20 years: A variety of factors seem to have contributed to this increased safety--better vehicle safety features, better road safety features, decreases in teenage drunk driving, more seat belt use, and at least recently, fewer vehicle miles traveled. In contrast, motorcycle riding, a topic of particular interest to the military, is becoming more dangerous. The main difference between the military and civilian population is the proportion of military crash fatalities on motorcycles--the U.S. rate is currently about 15 percent of fatalities, while in some military branches the rate is on average 35-40 percent. This review shows that the following safety interventions tend to help in the reduction of vehicle crashes and that some in particular may be useful in the military setting: (1) better enforcement of underage drinking laws and continuation of alcohol deglamorization campaigns (DoD regulations exist, but underage drinking seems to be relatively common); (2) high-visibility enforcement techniques for sobriety checkpoints; (3) high-visibility enforcement techniques for seat belt use; (4) adoption of a lower blood alcohol concentration level (such as 0.05) for motorcyclists, since the evidence shows that motorcyclists' ability to drive safely begins declining at lower levels than those for car drivers; (5) screening--perhaps as part of military medical assessment--and brief intervention with a trained counselor for at-risk drinkers, since they are at higher risk for drinking and driving; (6) media campaigns that are paired with community activities that also emphasize driver safety, such as workshops or fairs and with enforcement of driving regulations, and targeted at the drivers at highest risk (men in their teens and early 20s); (7) requirements that motorcyclists be licensed and own their vehicles.

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