Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Adding balance and mature perspectives on how all the chapters complement and sometimes challenge one another are Chapter 2, written by a major figure in the renaissance of the relevance to psychopathology of both genetics and personality; Chapters 15-17, informed critical appraisals citing concerns and cautions about premature applications of this information in the policy arena; and Chapter 18, a judicious contemplation by the editors themselves of this promisingAand, to some, alarmingAfield. Clear and meticulously researched, this eminently satisfying work is written to introduce the subject to postgraduate students just beginning to develop their research skills, to interested psychiatric practitioners, and to informed laypersons with some scientific background. In the 1960's and 1970's, personality and mental illness were conceptualized in an intertwined psychodynamic model. Biological psychiatry for many un-weaved that model and took mental illness for psychiatry and left personality to psychology. This book brings personality back into biological psychiatry, not merely in the form of personality disorder but as part of a new intertwined molecular genetic model of personality and mental disorder. This is the beginning of a new conceptual paradigm!! This breakthrough volume marks the beginning of a new era, an era made possible by the electrifying pace of discovery and innovation in the field of molecular genetics. In fact, several types of genome maps have already been completed, and todayAs experts confidently predict that we will have a smooth version of the sequencing of the human genomeAwhich contains some 3 billion base pairs Such astounding progress helped fuel the development of this remarkable volume, the first ever to discuss the brand-newAand often controversialAfield of molecular genetics and the human personality. Many chapters (6, 7, 9, 11, and 13) emphasize the neurodevelopmental and ontogenetic aspects of personality, with a major emphasis on the receptors and transporters for the neurotransmitters dopamine and serotonin. Though these neurotransmitters are a rational starting point now, the future undoubtedly will bring many other candidate genes that today cannot even be imagined, given our ignorance of the genes involved in the prenatal development of the central nervous system. -Chapter 3 provides an integrative overview of the broad autism phenotype, and as such will be of special interest to child psychiatrists. Chapters 5, 8, and 10 offer enlightening information on drug and alcohol abuse. Chapter 14 discusses variations in sexuality. Questioning, critical, and strong on methodological principles, this volume reflects the point of view of its 35 distinguished contributorsAall pioneers in this burgeoning field and themselves world-class theoreticians, empiricists, clinicians, developmentalists, and statisticians. For students of psychopathology and others bold enough to hold in abeyance their understandable misgivings about the conjunction of Amolecular geneticsA and Ahuman personality,A this work offers an authoritative and up-to-date introduction to the molecular genetics of human personality. The book, with its wealth of facts, conjectures, hopes, and misgivings, begins with a preface by world-renowned researcher and author Irving Gottesman. -The authors masterfully guide us through Chapter 1, principles and methods; Chapter 4, animal models for personality; and Chapter 11, human intelligence as a model for personality, laying the groundwork for our appreciation of the remaining empirical findings of human personality qua personality. This volume explores the era of study made possible by the pace of discovery im the field of molecular genetics. It seeks to offer an authoritative introduction to and discussion of the controversial field of molecular genetics and human personality.

#PBIB:2002.4 --- Behavior genetics. --- Genetic psychology. --- Molecular genetics. --- Personality. --- Personality Disorders --- Genetics, Behavioral. --- genetics. --- Genetics. --- Behavior genetics --- Genetic psychology --- Molecular genetics --- Personality --- Personal identity --- Personality psychology --- Personality theory --- Personality traits --- Personology --- Traits, Personality --- Psychology --- Individuality --- Persons --- Self --- Temperament --- Genetics --- Molecular biology --- Human genetics --- Behavior genetic analysis --- Behavioral genetics --- Human behavior genetics --- Psychogenetics

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Oxytocin (OT) and arginine vasopressin (AVP) are the paramount social hormones in mammals and accumulating evidence also strengthens the unique role of these neuropeptides also in human social behavior. Indeed from voles to humans, OT and AVP modulate an intriguing number of social behaviors resonating across species such as the quality of pair bonding, parenting, modulations of social stress, in-group & out-group relationships and social communications. Recent molecular genetic studies of the oxytocin (OXTR), arginine vasopressin 1a (AVPR1a) and arginine vasopressin 1b (AVPR1b) receptors have strengthened the role of these two neuropeptides in a range of normal and pathological human behaviors. Importantly, dysfunctions in the OT and AVP neural pathways are likely contributing to deficits in social skills and communication in disorders such as autism. This Research Topic covers the state of the science and provides a deep view of social hormone research in humans to illustrates how pharmacological, genetic and neuroimaging strategies can be successfully combined toward unraveling the mystery of how human social behavior is regulated. Understanding human social behavior at the molecular level, i.e. social neuroscience, is not only crucial for treatment and diagnosis of disorders characterized by deficits in social cognition but also has important implications in establishing the congruence of findings from different approaches in the Social Sciences and Biology. We bring together in this issue a broad spectrum of investigators from the neurosciences, genetics, psychology, economics and political science towards a deeper understanding of the biological roots of human social behavior. We hope that this transdisciplinary Research Topic will bring new insights and ideas to the field, give future perspectives while also addressing open questions and limitation in order to develop intervention and prevention strategies, and to translate the basic social hormone research into clinical applications. This Research Topic covers the state of the science and provides a deep view of social hormone research in humans to illustrates how pharmacological, genetic and neuroimaging strategies can be successfully combined toward unraveling the mystery of how human social behavior is regulated. Understanding human social behavior at the molecular level, aka social neuroscience, is not only crucial for treatment and diagnosis of disorders characterized by deficits in social cognition but such an understanding has important implications for consilience of the Social Sciences and Biology. We bring together in this issue a broad spectrum of investigators from the neurosciences, genetics, psychology, economics and political science towards a deeper understanding of the biological roots of human social behavior. We hope that this transdisciplinary Research Topic will bring new insights and ideas to the field, give future perspectives while also addressing open questions and limitation in order to develop intervention and prevention strategies, and to translate the basic social hormone research into clinical applications.

Human behavior. --- Hormones. --- receptor --- Oxytocin --- receptors --- Social Behavior --- CD38 --- intranasal --- Psychiatry