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Oxidative stress and biomaterials
Authors: ---
ISBN: 0128032707 0128032693 9780128032701 9780128032695 Year: 2016 Publisher: London, UK


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Oxidative stress and biomaterials
Authors: ---
ISBN: 9780128032701 0128032707 Year: 2016 Publisher: London, UK Academic Press is an imprint of Elsevier

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Abstract

Oxidative Stress and Biomaterials provides readers with the latest information on biomaterials and the oxidative stress that can pose an especially troubling challenge to their biocompatibility, especially given the fact that, at the cellular level, the tissue environment is a harsh landscape of precipitating proteins, infiltrating leukocytes, released oxidants, and fluctuations of pH which, even with the slightest shift in stasis, can induce a perpetual state of chronic inflammation. No material is 100% non-inflammatory, non-toxic, non-teratogenic, non-carcinogenic, non-thrombogenic, and non-immunogenic in all biological settings and situations. In this embattled terrain, the most we can hope for from the biomaterials we design is a type of "meso-compatibility, a material which can remain functional and benign for as long as required without succumbing to this cellular onslaught and inducing a local inflammatory reaction.

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