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This book presents the state of the art in the synthesis very complex saccharide structures, written by leading scientists at the forefront of this rapidly growing field. Reflecting the particular significance in recent years of efficient and selective procedures employing enzymes for preparative purposes in the carbohydrate field, a major proportion of the articles focus on these biocatalytic methods. In addition, recent strategies for the construction of unusual carbohydrates structures employing novel and creative methodologies are highlighted. Further, particular emphasis is placed on very complex saccharide structures as well as on special solutions to problems that are particularly challenging.
Carbohydrates --- Oligosaccharides --- Glycoconjugates --- Glycoconjugués --- Synthesis. --- Synthèse. --- Chemistry. --- Organic chemistry. --- Biochemistry. --- Organic Chemistry. --- Biochemistry, general. --- Glycoconjugués --- Synthèse. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Organic chemistry --- Composition --- Carbohydrates - Synthesis. --- Oligosaccharides - Synthesis. --- Glycoconjugates - Synthesis. --- OLIGOSACCHARIDES --- OLIGOSACCHARIDES, CONJUGATES --- GLYCOSIDE HYDROLASES --- LIPASES --- SIALIC ACIDS --- GLYCOSYLATION --- GLYCOPEPTIDES --- ERGOT ALKALOIDS --- PREPARATION
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The synthesis of very complex saccharide structures is one of the most challenging areas of modern glycoscience. This volume presents the state of the art of complex carbohydrate synthesis, written by leading scientists whose groups are making major contributions in the field. Reflecting the particular interest in inhibitors and modulators as well as in mimetics, an in-cepth treatment is given both of their selective syntheses and of their biological implications. In addition the concept of multivalent glycoconjugate recognition as well as supramolecular implications of amphiphilic carbohydrates are highlighted.
Chemistry. --- Organic chemistry. --- Biochemistry. --- Organic Chemistry. --- Biochemistry, general. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Organic chemistry --- Composition
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