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5-HT2A receptors are G-protein coupled receptors that are widely distributed throughout the brain, most notably on neuronal and glial cells. 5-HT2A receptors have been implicated in various central physiological functions including mood regulation, memory, sleep, nociception, eating, and reward behaviors, and they are also believed to control the cardiovascular system. This  book provides a comprehensive overview of these receptors including sections on their properties and distribution, approaches for their study, their role in a number of brain functions and diseases, and their role as therapeutic targets.

Serotonin --- Central nervous system. --- Receptors. --- Medicine. --- Neurosciences. --- Neurobiology. --- Biomedicine. --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Neurosciences

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5-HT2A receptors are G-protein coupled receptors that are widely distributed throughout the brain, most notably on neuronal and glial cells. 5-HT2A receptors have been implicated in various central physiological functions including mood regulation, memory, sleep, nociception, eating, and reward behaviors, and they are also believed to control the cardiovascular system. This  book provides a comprehensive overview of these receptors including sections on their properties and distribution, approaches for their study, their role in a number of brain functions and diseases, and their role as therapeutic targets.

Physiology of nerves and sense organs --- Neuropathology --- neurologie --- neurobiologie

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This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and pathology of the substantia nigra pars compacta (SNc) dopaminergic neurons. The single chapters, written by top scientists in their fields, explore the life cycle of dopaminergic neurons from their birth to death, the cause of Parkinson's disease, the second most common and disabling condition in the elderly population. Nevertheless, the intracellular cascade of events leading to dopamine cell death is still unknown and, consequently, treatment is symptomatic rather than preventive. The mechanisms by which alterations cause neuronal death, new therapeutic approaches and the latest evidence of a possible de novo neurogenesis in the SNc are reviewed and singled out in different chapters. This book bridges basic science and clinical practice and will prepare the reader for the next few years, which will surely be eventful in terms of the progress of dopamine research.

Dopaminergic neurons. --- Neurotransmitters. --- Parkinson’s disease -- Treatment. --- Substantia nigra. --- Dopaminergic neurons --- Substantia nigra --- Neurotransmitters --- Dopamine --- Parkinson Disease --- Substantia Nigra --- Physiology --- Neurons --- Catecholamines --- Neurodegenerative Diseases --- Biological Science Disciplines --- Cells --- Parkinsonian Disorders --- Tegmentum Mesencephali --- Nervous System --- Mesencephalon --- Anatomy --- Movement Disorders --- Biogenic Monoamines --- Natural Science Disciplines --- Basal Ganglia Diseases --- Amines --- Nervous System Diseases --- Brain Diseases --- Brain --- Disciplines and Occupations --- Central Nervous System Diseases --- Diseases --- Biogenic Amines --- Organic Chemicals --- Brain Stem --- Central Nervous System --- Chemicals and Drugs --- Neuroscience --- Neurology --- Medicine --- Human Anatomy & Physiology --- Health & Biological Sciences --- Black substance (Neuroanatomy) --- Body of Vicq d'Azyr --- Locus niger (Neuroanatomy) --- Nigra (Neuroanatomy) --- Nucleus niger (Neuroanatomy) --- Soemmering's ganglion --- Dopamine neurons --- Medicine. --- Neurology. --- Medicine & Public Health. --- Dopaminergic mechanisms --- Nervous system --- Neuropsychiatry --- Neurology .

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G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses. They dimerize (form a pair of macromolecules) with a wide variety of other receptors. The proposed book will provide a comprehensive overview of GPCR dimers, starting with a historical perspective and including, basic information about the different dimers, how they synthesize, their signaling properties, and the many diverse physiological processes in which they are involved.  In addition to presenting information about healthy GPCR dimer activity, the book will also include a section on their pathology and therapeutic potentials.

Medicine. --- Neurosciences. --- Biomedicine. --- Neural sciences --- Neurological sciences --- Neuroscience --- Clinical sciences --- Medical profession --- Medical sciences --- Nervous system --- Human biology --- Life sciences --- Pathology --- Physicians