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Medicines for Cancer: Mechanism of Action and Clinical Pharmacology of Chemo, Hormonal, Targeted, and Immunotherapies covers most known anti-cancer therapeutics. Cancer is the second leading cause of death worldwide, with its various forms resulting in nearly one out of every six mortalities each year. This book describes all US FDA-approved drugs (up to 2021), such as small molecules, peptides, monoclonal antibodies, whole antibodies, gene therapy, antibody-drug conjugates, cell therapy, and immunotherapies, along with information on their generic and brand names, medical uses, details dosage, mechanisms of actions, pharmacokinetics and side effects. Chemical structures of small molecules, small peptides, antibody-drug conjugates are also provided. This book is ideal for medicinal chemists, oncologists, and pharmacologists, but it will also be indispensable for professional researchers, whether they are working in the clinic or the pharmaceutical industry.

Cancer --- Clinical pharmacology. --- Chemotherapy. --- Neoplasms --- Pharmacology, Clinical --- drug therapy

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This book covers the important role small molecules can play in the modulation of stress-activated protein kinase (SAPK), also called the mitogen-activated protein kinase (MAPK) pathway, and the potential this may offer in enabling the development of future medicine therapies. It is clear that MAP kinase pathway therapies could continue to drive increasing interest in the field, both within academic laboratories and also in the biotechnology and pharmaceutical sectors. This book provides an overview of protein kinase inhibitors, the biological roles of MAP kinases, ATP-competitive and non-competitive inhibitors, covalent inhibitors, and more. This book is intended for professors in academia, researchers in pharmaceutical and biotechnology sectors working on protein kinases, and graduate students in pharmacy/chemistry.

Drug delivery systems. --- Pharmacology. --- Pharmacy. --- Drug Delivery.