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La mise à disposition des agents de contraste ultrasonores a introduit une nouvelle dimension dans l'examen échographique avec la possibilité d'une exploration en temps réel de la cinétique de prise de contraste de lésions variées. Les indications potentielles de ces microbulles touchent la quasi-totalité des organes profonds et superficiels, mais également les possibilités d'études pharmacologiques pour la néo-angiogenèse ou le guidage thérapeutique par méthodes physiques. Enfin de nouvelles applications se font jour dans le domaine des produits ciblés et le transport de principes actifs. Il

Diagnostic ultrasonic imaging. --- Diagnosis, Ultrasonic --- Diagnostic sonography --- Diagnostic ultrasonics --- Diagnostic ultrasonography --- Diagnostic ultrasound --- Medical diagnostic ultrasonic imaging --- Medical ultrasonography --- Ultrasonic diagnosis --- Ultrasonic diagnostic imaging --- Ultrasonic imaging --- Ultrasonic waves --- Diagnostic imaging --- Ultrasonics in medicine --- Diagnostic use

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In recent years, the imaging-based diagnosis of mass liver lesions has become increasingly complex due to the number and morphological variability of lesions that modern imaging techniques are currently able to display. If the sensitivity in detection has greatly increased, characterisation has remained difficult and represents a critical challenge for the clinician. The availability of blood-pool contrast agents for ultrasound (US), in particular second-generation US contrast agents based on perfluorocarbon- or sulfur-hexafluoride-filled microbubbles, and the development of contrast-specific software and technologies have opened up new perspectives both for the immediate characterisation of any mass lesion detected in the liver and for increasing the sensitivity of US in the detection of liver metastases. Taking into account the great impact of this new technology on clinical practice, the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) organised, in January 2004, in Rotterdam, a consensus meeting of experts in order to develop guidelines for the use of US contrast agents in the diagnosis of liver diseases . These guidelines, as well as discussions of further advances in the clinical application of contrast-enhanced harmonic US are presented in this book by an internationally renowned group of experts. The book represents provides an important starting point for clinical implementation of this new diagnostic procedure.

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Color makes its way into natural science images as early as the research process. It serves for self-reflection and for communication within the scientific community. However, color does not follow a standard in the natural sciences: its meaning is contingent, even though culturally conditioned. Digital publishing enhances the use of color in scientific publications; at the same time, globalization promotes the idea of universal color symbolism. This book investigates the function of color in historical and current visualizations for scientific purposes, its epistemic role as a tool, and its long neglect due to symbolic and gender-specific connotations. The publication thus closes a research gap in the natural sciences and the humanities. Color makes its way into natural science images as early as the research process. It serves for self-reflection and for communication within the scientific community. However, color does not follow a standard in the natural sciences: its meaning is contingent, even though culturally conditioned. Digital publishing enhances the use of color in scientific publications; at the same time, globalization promotes the idea of universal color symbolism. This book investigates the function of color in historical and current visualizations for scientific purposes, its epistemic role as a tool, and its long neglect due to symbolic and gender-specific connotations. The publication thus helps to bridge a long standing research gap in the natural sciences and the humanities.

Color. --- Chromatics --- Colour --- Chemistry --- Light --- Optics --- Colors --- Thermochromism --- Image, Color, Science.