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Extracellular vesicles (EVs) are particles wrapped in a lipid bilayer membrane and are naturally released from cells. This kind of cargo vessel is a nanostructure that mainly transfers lipids, proteins, various nucleic acid fragments, and metabolic components to neighboring cells or distant parts of the body through the circulatory system. EVs are of great significance to the communication mechanism between cells. This book collects feature articles to enhance our understanding of the biological characteristics of EVs and their potential applications.

Medicine --- extracellular vesicle --- precision oncology --- cancer biomarker --- prostate cancer --- drug delivery --- extracellular vesicles --- lysosome --- nanocarriers --- ultrasound --- size exclusion chromatography --- differential ultracentrifugation --- head and neck squamous cell carcinoma (HNSCC) --- exosomes --- cancer --- biomarker --- diagnostic --- therapy --- liquid biopsy --- small extracellular vesicles (sEV) --- tumor-derived exosomes (TEX) --- melanoma cell-derived exosomes (MTEX) --- proteomics --- tumor microenvironment --- biomarkers --- ectosomes --- neoplasia --- microvesicles --- small extracellular vesicles --- isolation --- purification --- size-exclusion chromatography --- ultracentrifugation --- sucrose density cushion --- lymph node --- spleen --- solid tissue --- microvesicle --- exosome --- cancer therapeutic --- drug carrier --- flow cytometry --- immunophenotyping --- swarm detection --- tumor-associated macrophages --- macrophage polarization --- mannose receptor --- HIV-1 Nef --- glioblastoma --- microRNA --- immunoprecipitation --- CD44 --- human milk --- nutrient --- microbiota --- microRNAs --- nanocommunicator --- diagnostic biomarker --- drug delivery vehicle --- personalized cancer immunotherapy --- therapeutic agents --- cell-to-cell communication --- ionising radiation --- non-targeted effects --- signalling --- imaging flow cytometry --- biomarker reservoirs --- cancer diagnostics --- disease monitoring --- large EVs --- ovarian cancer cells --- ES-2 --- OAW-42 --- adipose tissue origin mesenchymal stem cells --- n/a

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Extracellular vesicles (EVs) are particles wrapped in a lipid bilayer membrane and are naturally released from cells. This kind of cargo vessel is a nanostructure that mainly transfers lipids, proteins, various nucleic acid fragments, and metabolic components to neighboring cells or distant parts of the body through the circulatory system. EVs are of great significance to the communication mechanism between cells. This book collects feature articles to enhance our understanding of the biological characteristics of EVs and their potential applications.

Medicine --- extracellular vesicle --- precision oncology --- cancer biomarker --- prostate cancer --- drug delivery --- extracellular vesicles --- lysosome --- nanocarriers --- ultrasound --- size exclusion chromatography --- differential ultracentrifugation --- head and neck squamous cell carcinoma (HNSCC) --- exosomes --- cancer --- biomarker --- diagnostic --- therapy --- liquid biopsy --- small extracellular vesicles (sEV) --- tumor-derived exosomes (TEX) --- melanoma cell-derived exosomes (MTEX) --- proteomics --- tumor microenvironment --- biomarkers --- ectosomes --- neoplasia --- microvesicles --- small extracellular vesicles --- isolation --- purification --- size-exclusion chromatography --- ultracentrifugation --- sucrose density cushion --- lymph node --- spleen --- solid tissue --- microvesicle --- exosome --- cancer therapeutic --- drug carrier --- flow cytometry --- immunophenotyping --- swarm detection --- tumor-associated macrophages --- macrophage polarization --- mannose receptor --- HIV-1 Nef --- glioblastoma --- microRNA --- immunoprecipitation --- CD44 --- human milk --- nutrient --- microbiota --- microRNAs --- nanocommunicator --- diagnostic biomarker --- drug delivery vehicle --- personalized cancer immunotherapy --- therapeutic agents --- cell-to-cell communication --- ionising radiation --- non-targeted effects --- signalling --- imaging flow cytometry --- biomarker reservoirs --- cancer diagnostics --- disease monitoring --- large EVs --- ovarian cancer cells --- ES-2 --- OAW-42 --- adipose tissue origin mesenchymal stem cells --- extracellular vesicle --- precision oncology --- cancer biomarker --- prostate cancer --- drug delivery --- extracellular vesicles --- lysosome --- nanocarriers --- ultrasound --- size exclusion chromatography --- differential ultracentrifugation --- head and neck squamous cell carcinoma (HNSCC) --- exosomes --- cancer --- biomarker --- diagnostic --- therapy --- liquid biopsy --- small extracellular vesicles (sEV) --- tumor-derived exosomes (TEX) --- melanoma cell-derived exosomes (MTEX) --- proteomics --- tumor microenvironment --- biomarkers --- ectosomes --- neoplasia --- microvesicles --- small extracellular vesicles --- isolation --- purification --- size-exclusion chromatography --- ultracentrifugation --- sucrose density cushion --- lymph node --- spleen --- solid tissue --- microvesicle --- exosome --- cancer therapeutic --- drug carrier --- flow cytometry --- immunophenotyping --- swarm detection --- tumor-associated macrophages --- macrophage polarization --- mannose receptor --- HIV-1 Nef --- glioblastoma --- microRNA --- immunoprecipitation --- CD44 --- human milk --- nutrient --- microbiota --- microRNAs --- nanocommunicator --- diagnostic biomarker --- drug delivery vehicle --- personalized cancer immunotherapy --- therapeutic agents --- cell-to-cell communication --- ionising radiation --- non-targeted effects --- signalling --- imaging flow cytometry --- biomarker reservoirs --- cancer diagnostics --- disease monitoring --- large EVs --- ovarian cancer cells --- ES-2 --- OAW-42 --- adipose tissue origin mesenchymal stem cells

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Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments’ side effects. In the past, clinical data showed that some complementary and alternative medicine (CAM) possessed anticancer abilities, but some clinicians and scientists have queried about the scientific validity of CAM due to the lack of scientific evidence. There is great demand in narrowing the knowledge gap to explore the scientific and evidence-based knowledge of CAM in the anticancer field. With this aim, an unparalleled undertaking of a book series is launched to structurally consolidate this area. Although acupuncture and moxibustion have been practiced for millennia, they have come under scientific investigation only recently. Acupuncture and moxibustion have been used clinically to treat cancer-related symptoms (e.g. cancer pain, anxiety, depression and insomnia), manage treatment-induced side effects (e.g. hot flashes, nausea and vomiting) and enhance immunity (e.g. blood cell count, lymphocyte and natural killer cell activity). This is the first book manages to provide comprehensive and updated scientific evidence of the effectiveness of acupuncture and moxibustion intervention for cancer care. Laboratory and animal studies have uncovered the mechanisms of acupuncture and moxibustion for cancer therapy. Promising results of most clinical trials show the efficacy and safety of acupuncture and moxibustion in cancer management. This book consists of fifteen chapters which address a range of important aspects that will impact on the application of acupuncture and moxibustion. An overview of the safety and side effects of acupuncture and moxibustion for cancer care are also covered. In addition, the integration of acupuncture with Western medicine in cancer treatment and recent clinical trials are included as well. Opinion leaders around the world have teamed up to pursue a thorough and up-to-date review of the area, this volume will contribute great to the cancer, clinical and academic community by providing evidence-based information on the efficacy of acupuncture and moxibustion as an anticancer therapy.

Acupuncture points. --- Acupuncture. --- Moxa. --- Cancer --- Acupuncture --- Moxa --- Evidence-based medicine --- Evidence-Based Practice --- Complementary Therapies --- Clinical Medicine --- Diseases --- Medicine --- Therapeutics --- Health Occupations --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Disciplines and Occupations --- Moxibustion --- Evidence-Based Medicine --- Neoplasms --- Acupuncture Therapy --- Health & Biological Sciences --- Oncology --- Alternative Medicine --- Alternative treatment --- Treatment. --- Cancer therapy --- Cancer treatment --- Acumoxa --- Moxabustion --- Therapy --- Medicine. --- Cancer research. --- Complementary medicine. --- Oncology. --- Medicine & Public Health. --- Complementary & Alternative Medicine. --- Biomedicine general. --- Cancer Research. --- Counterirritation --- Energy medicine --- Tumors --- Complementary medicine --- Healing systems --- Systems, Healing --- Systems, Therapeutic --- Therapeutic systems --- Integrative medicine --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Acupuncture points --- Alternative medicine. --- Oncology  . --- Biomedicine, general. --- Health Workforce

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Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments’ side effects. In the past, clinical data showed that some complementary and alternative medicine (CAM) possessed anticancer abilities, but some clinicians and scientists have queried about the scientific validity of CAM due to the lack of scientific evidence. There is great demand in the knowledge gap to explore the scientific and evidence-based knowledge of CAM in the anticancer field. With this aim, a book series is needed to structurally deliver the knowledge to readers. Throughout the past decade, the cancer chemopreventive potencies and treatment effects of a number of natural dietary agents present in different food sources have been evaluated by various experiments. Some of them have progressed to early clinical trials. This volume is a specialized book presenting the research evidence relevant to the use of specific diet therapy in cancer chemoprevention and treatment. We begin with lessons learned from dietary resveratrol as an effective agent with anticancer properties against malignancies, followed examples of flavonoids from fruits and vegetables in the prevention and treatment of cancer. Evidence for the beneficial influence of diet enriched with flax seed oil and green tea on cancer will be reviewed. Soy food intake may enhance the effects on anticancer treatment for breast cancer, whereas lycopene-rich foods may possess chemopreventive efficacy. There are also discussions on the contribution of the cancer preventive effects of the antioxidant-rich foods and Mediterranean diet. In addition, the modulation of proteasome pathways by nutraceuticals is highlighted. Finally, we close the book with a discussion on the attenuation of cell survival signaling by bioactive phytochemicals in the prevention and therapy cancer.

Cancer -- Chemoprevention. --- Cancer -- Diet therapy. --- Cancer. --- Antineoplastic Agents --- Protective Agents --- Drug Therapy --- Diseases --- Therapeutic Uses --- Specialty Uses of Chemicals --- Therapeutics --- Physiological Effects of Drugs --- Chemical Actions and Uses --- Pharmacologic Actions --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Chemicals and Drugs --- Anticarcinogenic Agents --- Chemoprevention --- Neoplasms --- Cancer --- Diet therapy. --- Nutritional aspects. --- Medicine. --- Cancer research. --- Biotechnology. --- Complementary medicine. --- Oncology. --- Health. --- Biomedicine. --- Biomedicine general. --- Complementary & Alternative Medicine. --- Popular Science in Medicine and Health. --- Cancer Research. --- Nutritional aspects --- Treatment --- Alternative medicine. --- Oncology  . --- Tumors --- Chemical engineering --- Genetic engineering --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Complementary medicine --- Healing systems --- Systems, Healing --- Systems, Therapeutic --- Therapeutic systems --- Medicine --- Integrative medicine --- Medicine . --- Biomedicine, general. --- Health Workforce --- Cancer research --- Personal health --- Wellness --- Physiology --- Holistic medicine --- Hygiene --- Well-being --- diet therapy. --- prevention & control. --- methods. --- therapeutic use.

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Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments’ side effects. In the past, clinical data showed that some complementary and alternative medicine (CAM) possessed anticancer abilities, but some clinicians and scientists have queried about the scientific validity of CAM due to the lack of scientific evidence. There is great demand in the knowledge gap to explore the scientific and evidence-based knowledge of CAM in the anticancer field. With this aim, a book series is needed to structurally deliver the knowledge to readers. Integrative therapies comprise a variety of non-pharmacological interventions that assist in alleviating physical and psychological symptoms. Apart from being a life-threatening disease, cancer and its therapy are usually associated with a significant deterioration in the quality of life. There is growing evidence that non-pharmacological therapies provide symptom and pain management in cancer palliation. This volume is a specialised book presenting the research evidence relevant to the application of a range of commonly used non-pharmacological interventions in supportive cancer care, including massage, acupressure, Qigong, yoga, mind-body therapy, mindfulness-based intervention, and aromatherapy. A number of scientific researches and clinical studies support that these therapies offer potential beneficial effects for cancer patients in terms of reducing pain, anxiety, and other symptoms. Indeed, non-pharmacological therapies are increasingly gaining acceptance in the healthcare community as complementary to conventional cancer treatments. Most of them are non-invasive, inexpensive, and useful in improving quality of life, and they may be accessed by patients themselves.

Cancer -- Palliative treatment. --- Cancer --Patients -- Rehabilitation. --- Neoplasms --rehabilitation -- Great Britain. --- Patient Care Team --Great Britain. --- Cancer --- Patient Care --- Therapeutics --- Evidence-Based Practice --- Clinical Medicine --- Diseases --- Medicine --- Therapeutic Uses --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Health Occupations --- Pharmacologic Actions --- Health Services --- Disciplines and Occupations --- Chemical Actions and Uses --- Health Care Facilities, Manpower, and Services --- Chemicals and Drugs --- Health Care --- Palliative Care --- Evidence-Based Medicine --- Integrative Medicine --- Antineoplastic Agents --- Neoplasms --- Complementary Therapies --- Health & Biological Sciences --- Oncology --- Alternative Medicine --- Palliative treatment --- Alternative treatment --- Palliative treatment. --- Alternative treatment. --- Alternative therapy --- Medicine. --- Cancer research. --- Complementary medicine. --- Acupuncture. --- Oncology. --- Medicine & Public Health. --- Complementary & Alternative Medicine. --- Biomedicine general. --- Cancer Research. --- Treatment --- Alternative medicine. --- Oncology  . --- Tumors --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Counterirritation --- Energy medicine --- Complementary medicine --- Healing systems --- Systems, Healing --- Systems, Therapeutic --- Therapeutic systems --- Integrative medicine --- Biomedicine, general. --- Health Workforce --- Cancer research