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The book focuses on the understanding of molecular pathways by which normal cell progress to the definable stage of cancer. The chapters explore microbiota and chronic inflammation, multiple myeloma chemoprevention, microRNAs, cancer regulation, liquid biopsies, and angiogenesis. Recent advances of molecular risk assessment, tumor microenvironment, microneoplasia, malignant gene expressions are highlighted to provide a means and design of future cancer prevention strategies and challenges thereupon. The volume also explores various receptor drugs that are in development process with the emphasis of inhibitors used to prevent malignant gene expression. The book bridges the gap between basic science and clinical application of current knowledge of cancer and emphasizes that tumor progression and cancer metastasis are not random - treatments and cure are logical and eventual. Expertly authored and drawing from a wealth of international perspectives, Molecular Targets and Strategies in Cancer Prevention is invaluable reading for clinicians and researchers in the fields of oncology and molecular biology.

Medicine. --- Cancer research. --- Molecular biology. --- Oncology. --- Biomedicine. --- Cancer Research. --- Molecular Medicine. --- Cancer --- Prevention. --- Molecular aspects. --- Oncology  . --- Tumors --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Health Workforce --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Cancer research

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The abnormal behavior of all cancer cells regardless of cancer type is irregular cell signaling pathway activity. A mechanistic approach dealing with a fundamental and molecular view based signaling cascade are exciting and dynamic areas of cancer research. This book illuminates what we know, how we know and what remains to be discovered in this regard. The book explore and identify not only the key compounds of cell signaling pathway but also the interaction between them, the cross-talk. This book bring together up-to-date summaries of the signaling components that are likely to be used in diagnosis, prognosis and novel target for pharmaceutical intervention and therapeutic development and highlight the importance of molecular approach to clinical cancer research. A lot clinical trials and outcome are promising. The translation of recent advance in the knowledge of intracellular signaling into the generation of innovative molecular targeted cancer therapy are essential features of this book. Goals are manifold such as, resensitise chemoresistant target, capitalize on different mechanism of action and gain an advantage in the identification of best combination of drugs to induce clinically relevant response. The expert review compile in this book is an invaluable resource for graduate researcher and established scientist working in cell biology, pharmacy, experimental and molecular therapeutics and molecular medicine.

Cancer -- Treatment. --- Cancer cells. --- Cellular signal transduction. --- Cellular signal transduction --- Cancer --- Cancer cells --- Biochemical Processes --- Therapeutics --- Diseases --- Cell Physiological Processes --- Biological Science Disciplines --- Chemical Processes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Cell Physiological Phenomena --- Biochemical Phenomena --- Natural Science Disciplines --- Phenomena and Processes --- Chemical Phenomena --- Disciplines and Occupations --- Drug Therapy --- Neoplasms --- Signal Transduction --- Molecular Targeted Therapy --- Physiology --- Medicine --- Health & Biological Sciences --- Oncology --- Treatment --- Molecular aspects. --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Medicine. --- Cancer research. --- Pharmacology. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Cells --- Pathology, Cellular

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The abnormal behavior of all cancer cells regardless of cancer type is irregular cell signaling pathway activity. A mechanistic approach dealing with a fundamental and molecular view based signaling cascade are exciting and dynamic areas of cancer research. This book illuminates what we know, how we know and what remains to be discovered in this regard. The book explore and identify not only the key compounds of cell signaling pathway but also the interaction between them, the cross-talk. This book bring together up-to-date summaries of the signaling components that are likely to be used in diagnosis, prognosis and novel target for pharmaceutical intervention and therapeutic development and highlight the importance of molecular approach to clinical cancer research. A lot clinical trials and outcome are promising. The translation of recent advance in the knowledge of intracellular signaling into the generation of innovative molecular targeted cancer therapy are essential features of this book. Goals are manifold such as, resensitise chemoresistant target, capitalize on different mechanism of action and gain an advantage in the identification of best combination of drugs to induce clinically relevant response. The expert review compile in this book is an invaluable resource for graduate researcher and established scientist working in cell biology, pharmacy, experimental and molecular therapeutics and molecular medicine.

Pharmacology. Therapy --- Oncology. Neoplasms --- farmacologie --- toxicologie --- oncologie