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"A fascinating set of reviews, many of theoretical interest or practical import. 21st Century neurobiology will concentrate on modulating arousal states, as examined in this book. Further, the subject is amenable to thorough genetic analysis, this providing a useful output for modern molecular neurobiology." Donald W. Pfaff, Ph.D., The Rockefeller University "Sleep is an essential biological activity that is intimately connected to the neuroendocrine, autonomic and immune systems of the body. Written by an international cadre of researchers, this timely volume gives an up-to-date summary of the reciprocal influences of sleep-waking activity on neuroendocrine, autonomic and immune function. Chapters in this volume discuss the many mediators involved in sleep regulation, the consequences of sleep deprivation and shift work and dysregulation of neuroendocrine function in sleep-related disorders, among other topics. It should be a valuable resource for basic and clinical researchers." Bruce S. McEwen, Ph.D., The Rockefeller University Neuroendocrine Correlates of Sleep/Wakefulness emerges from three well-established disciplines - neuroendocrinology, neurochemistry of sleep/wakefulness, and sleep medicine...The readers will find also in depth information on neuroendocrine and behavioral correlates of sleep deprivation, circadian rhythms, affective disorders, obstructive sleep apnea, restless legs syndrome and infectious diseases. Daniel P. Cardinali and S.R. Pandi-Perumal have edited a book that is clear, comprehensive, well balanced and remarkably complete. This volume will be of interest to a wide circle of readers including neuroendocrinologists, neurologists, psychiatrists psychologists and sleep medicine specialists who evaluate and/or treat patients with sleep disorders. Jaime M. Monti, M.D., Clinics Hospital, School of Medicine " When I first saw the title of this scholarly, up-to-date, and comprehensive multi-author book on the Neuroendocrine Correlates of Sleep and Wakefulness , I could not but think of a 400 BCE tome similarly entitled On Sleep and Sleeplessness, by Aristotle. How far has science gone in understanding the mechanisms of sleep and wakefulness and the pivotal physiologic and pathologic roles of sleep? Sleep and wakefulness constitute major homeostatic systems, whose proper function is crucial to the health and happiness of the individual. Both systems operate at the intersection of the nervous, endocrine, metabolic and immune systems, and their homeostatic mediators include all kinds of molecules, such as neurotransmitters, neuropeptides, hormones and cytokines. This book succeeds in providing, to large extent, the state-of the-art robust knowledge in this important area of science and medicine". George P. Chrousos, M.D., University of Athens, Athens and National Institute of Child Health and Human Development, National Institutes of Health, Bethesda MD.
Sleep --- Wakefulness --- Neuropharmacology. --- Endocrine aspects. --- Nervous system --- Neurotropic drugs --- Sleeplessness --- Sleeping --- Slumber --- Drug effects --- Effect of drugs on --- Neuroendocrinology. --- Sleep -- Endocrine aspects. --- Sleep -- Physiology. --- Wakefulness -- Endocrine aspects. --- Wakefulness -- Physiology. --- Neuropharmacology --- Neuroendocrinology --- Medicine. --- Human physiology. --- Neurosciences. --- Endocrinology. --- Biomedicine. --- Human Physiology. --- Neurosciences --- Pharmacology --- Arousal (Physiology) --- Consciousness --- Sleep-wake cycle --- Health --- Psychophysiology --- Rest --- Subconsciousness --- Dreams --- Hypnagogia
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During the last few decades, sleep medicine and science, and many of their diverse aspects, have emerged as areas of intense medical and scientific interest. Of these, sleep and neuroimmunology, which cut across many behavioral states, are highly interlinked, inherently fascinating and touching upon many facets of human health and well-being. Elucidating the roles of immune substances and cells in central nervous system functions, especially their involvement in the regulation of sleep and wakefulness, may help unravel pathophysiologic mechanisms of sleep disorders and improve their management. Neuroimmunology of Sleep provides an introduction to the interphase between sleep and neuroimmunology. Written both from basic and clinical perspectives, the volume contains useful information to many biomedical professionals and students of human biology. This informative and forward-looking volume will be valuable to sleep researchers, neuroimmunologists, psychiatrists, psychologists, neurologists, and all physicians or health-care professionals who evaluate and treat patients with sleep problems. In addition, this volume will be helpful to medical students and clinicians of various disciplines who want to get an overall grasp of the neuroimmunology of sleep field. S.R. Pandi-perumal, MSc., Comprehensive Center for Sleep Medicine, Department of Pulmonary, Critical Care, and Sleep Medicine, Mount Sinai School of Medicine, New York, NY 10029, U.S.A. D.P. Cardinali, MD., PhD., Department of Physiology, Faculty of Medicine, University of Buenos Aires, Paraguay 2155, 1121, Buenos Aires, Argentina. G.P. Chrousos, MD, FAAP, MACP, MACE, First Department of Pediatrics, Athens University Medical School, Aghia Sophia Children's Hospital, 115 27 Athens, Greece and Reproductive Biology and Medicine Branch, National Institute of Child and Human Development (NICHD), Bethesda, MD, USA.
Neuroimmunology. --- Sleep --- Physiological aspects. --- Neuroimmunomodulation --- Immunology --- Neurosciences --- Immunology. --- Neurosciences. --- Pathology. --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Neural sciences --- Neurological sciences --- Neuroscience --- Nervous system --- Immunobiology --- Life sciences --- Serology
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Many recent discoveries in both laboratory and clinical settings have greatly increased our understanding of sleep medicine and the relevant psychopharmacology. This timely book serves to present updated information about the neuropsychopharmacology of sleep as this field enters mainstream psychiatry, neurology and medicine This volume has assembled articles that summarize and review carefully, a chosen selection of the latest discoveries concerning sleep medicine, sleep physiology and sleep pharmacology. Outstanding contributions have been sought from acknowledged experts in their respective fields. The goal of the volume is to present the more recent developments and advances in the fields of sleep and neuropsychopharmacology, as well as to provide a context for considering them both in depth and from multidisciplinary perspectives. This volume brings together the collective expertise of clinicians and basic researchers who represent a range of interests in neuroscience, neuropharmacology, sleep physiology, and biological rhythms. Presenting a thoughtful balance of basic experimental and clinical facts and viewpoints, this book will serve as a foundation for understanding, and ultimately treating, sleep disorders.
Biomedicine. --- Pharmacology/Toxicology. --- Neurosciences. --- Neuropsychology. --- Neurobiology. --- Medicine/Public Health, general. --- Medicine. --- Toxicology. --- Psychology, clinical. --- Médecine --- Neurosciences --- Toxicologie --- Neurobiologie --- Chronopharmacology. --- Neuropharmacology. --- Sleep -- Physiological aspects. --- Sleep disorders. --- Sleep --- Sleep disorders --- Neuropharmacology --- Chronopharmacology --- Psychology --- Sleep Disorders --- Physiology --- Drug Therapy --- Neurologic Manifestations --- Behavioral Sciences --- Psychophysiology --- Mental Disorders --- Nervous System Diseases --- Therapeutics --- Nervous System Physiological Processes --- Biological Science Disciplines --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Nervous System Physiological Phenomena --- Psychiatry and Psychology --- Natural Science Disciplines --- Psychological Phenomena and Processes --- Signs and Symptoms --- Behavioral Disciplines and Activities --- Diseases --- Pathological Conditions, Signs and Symptoms --- Disciplines and Occupations --- Musculoskeletal and Neural Physiological Phenomena --- Phenomena and Processes --- Neuroscience --- Pharmacy, Therapeutics, & Pharmacology --- Human Anatomy & Physiology --- Health & Biological Sciences --- Physiological aspects --- Physiological aspects. --- Nervous system --- Neurotropic drugs --- Disorders of sleep --- Drug effects --- Effect of drugs on --- Pharmacology. --- Pharmacology --- Psychology, Pathological --- Chronobiology --- Clinical psychology. --- Psychiatry --- Psychology, Applied --- Psychological tests --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Neural sciences --- Neurological sciences --- Chemicals --- Medicine --- Poisoning --- Poisons --- Toxicology --- Health Workforce --- Neurophysiology --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect
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During the last few decades, sleep medicine and science, and many of their diverse aspects, have emerged as areas of intense medical and scientific interest. Of these, sleep and neuroimmunology, which cut across many behavioral states, are highly interlinked, inherently fascinating and touching upon many facets of human health and well-being. Elucidating the roles of immune substances and cells in central nervous system functions, especially their involvement in the regulation of sleep and wakefulness, may help unravel pathophysiologic mechanisms of sleep disorders and improve their management. Neuroimmunology of Sleep provides an introduction to the interphase between sleep and neuroimmunology. Written both from basic and clinical perspectives, the volume contains useful information to many biomedical professionals and students of human biology. This informative and forward-looking volume will be valuable to sleep researchers, neuroimmunologists, psychiatrists, psychologists, neurologists, and all physicians or health-care professionals who evaluate and treat patients with sleep problems. In addition, this volume will be helpful to medical students and clinicians of various disciplines who want to get an overall grasp of the neuroimmunology of sleep field. S.R. Pandi-perumal, MSc., Comprehensive Center for Sleep Medicine, Department of Pulmonary, Critical Care, and Sleep Medicine, Mount Sinai School of Medicine, New York, NY 10029, U.S.A. D.P. Cardinali, MD., PhD., Department of Physiology, Faculty of Medicine, University of Buenos Aires, Paraguay 2155, 1121, Buenos Aires, Argentina. G.P. Chrousos, MD, FAAP, MACP, MACE, First Department of Pediatrics, Athens University Medical School, Aghia Sophia Children's Hospital, 115 27 Athens, Greece and Reproductive Biology and Medicine Branch, National Institute of Child and Human Development (NICHD), Bethesda, MD, USA.
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