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The BLyS/BAFF family of cytokines and receptors has captured and held the attention of B cell biologists during the last decade. Discovery of the two ligands and three receptors comprising this family has yielded a watershed of insights; fostering fresh paradigms in our views about the differentiation, selection, and homeostatic control of virtually all B cell subsets. Moreover, because these processes are intimately tied to the mechanistic underpinnings of immune tolerance and activation, increased understanding of these activities promises translational progress in autoimmunity, neoplasia, and transplantation.
B cells -- Differentiation. --- B cells. --- Cell receptors. --- Ligands (Biochemistry). --- Ligands. --- B cells --- Ligands (Biochemistry) --- Cell receptors --- Membrane Proteins --- Antibody-Producing Cells --- Lymphocytes --- Cell Physiological Processes --- Laboratory Chemicals --- B-Lymphocytes --- Ligands --- Receptors, Cell Surface --- Cell Differentiation --- Cells --- Cell Physiological Phenomena --- Leukocytes, Mononuclear --- Specialty Uses of Chemicals --- Immune System --- Proteins --- Leukocytes --- Phenomena and Processes --- Chemical Actions and Uses --- Hemic and Immune Systems --- Anatomy --- Amino Acids, Peptides, and Proteins --- Blood Cells --- Chemicals and Drugs --- Blood --- Biology --- Microbiology & Immunology --- Health & Biological Sciences --- Differentiation --- Autoimmunity. --- Autoallergy --- B lymphocytes --- Bone marrow derived cells --- Bursa equivalent cells --- Medicine. --- Immunology. --- Microbiology. --- Biomedicine. --- Immunity --- Autoantibodies --- Antigen presenting cells --- Microbial biology --- Microorganisms --- Immunobiology --- Life sciences --- Serology
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The BLyS/BAFF family of cytokines and receptors has captured and held the attention of B cell biologists during the last decade. Discovery of the two ligands and three receptors comprising this family has yielded a watershed of insights; fostering fresh paradigms in our views about the differentiation, selection, and homeostatic control of virtually all B cell subsets. Moreover, because these processes are intimately tied to the mechanistic underpinnings of immune tolerance and activation, increased understanding of these activities promises translational progress in autoimmunity, neoplasia, and transplantation.
General microbiology --- Immunology. Immunopathology --- immunologie --- microbiologie
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The BLyS/BAFF family of cytokines and receptors has captured and held the attention of B cell biologists during the last decade. Discovery of the two ligands and three receptors comprising this family has yielded a watershed of insights; fostering fresh paradigms in our views about the differentiation, selection, and homeostatic control of virtually all B cell subsets. Moreover, because these processes are intimately tied to the mechanistic underpinnings of immune tolerance and activation, increased understanding of these activities promises translational progress in autoimmunity, neoplasia, and transplantation.
General microbiology --- Immunology. Immunopathology --- immunologie --- microbiologie
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Mice --- immunology --- Immunology --- Congresses --- Immunology. --- Congresses. --- Mice - immunology - congresses
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