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Guanine rich DNA has been known for decades to form unusual structures, although their biological relevance was little understood. Recent advances have demonstrated that quadruplex structures can play a role in gene expression and provide opportunities for a new class of anticancer therapeutics. A number of quadruplex-specific proteins have also been discovered. Quadruplex Nucleic Acids discusses all aspects of the fundamentals of quadruplex structures, including their structure in solution and the crystalline state, the kinetics of quadruplex folding, and the role of cations in structure and

Molecular pharmacology --- Molecular biology --- Pharmacologie moléculaire --- Biologie moléculaire --- Quadruplex nucleic acids --- Nucleic Acid Conformation --- DNA --- Genetic Structures --- Nucleic Acids --- Molecular Conformation --- Genetic Phenomena --- Nucleic Acids, Nucleotides, and Nucleosides --- Molecular Structure --- Chemicals and Drugs --- Biochemical Phenomena --- Phenomena and Processes --- Chemical Phenomena --- Animal Biochemistry --- Human Anatomy & Physiology --- Health & Biological Sciences --- Pharmacologie moléculaire --- Biologie moléculaire

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PROTEINS --- PROTEIN FOLDING --- DENATURATION --- PROTEINS --- PROTEIN FOLDING --- DENATURATION