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Intended as a companion to the Fundamentals of Forensic DNA Typing volume published in 2009, Advanced Topics in Forensic DNA Typing: Methodology contains 18 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field and citation to more than 2800 articles and internet resources. The book builds upon the previous two editions of John Butler’s internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. This book provides the most detailed information written to-date on DNA databases, low-level DNA, validation, and numerous other topics including a new chapter on legal aspects of DNA testing to prepare scientists for expert witness testimony. Over half of the content is new compared to previous editions. A forthcoming companion volume will cover interpretation issues.

DNA fingerprinting. --- Forensic genetics. --- DNA fingerprints --- DNA identification --- DNA profiles --- DNA profiling --- Genetic fingerprinting --- Genetic fingerprints --- Forensic biology --- Genetics --- Medical jurisprudence --- Forensic genetics --- Identification --- Technique --- DNA Fingerprinting --- DNA --- Forensic Genetics --- methods --- physiology

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Since the enormously successful first edition of Forensic DNA Typing was published, the Human Genome Project has published a draft sequence of the human genome and completed the "finished? reference sequence. The advent of modern DNA technology has resulted in the increased ability to perform human identity testing-desirable in a number of situations including the determination of perpetrators of violent crime such as murder and rape, resolving unestablished paternity, and identifying remains of missing persons or victims of mass disasters. The technology has been utilized in identifying remai

DNA fingerprinting. --- DNA --- Forensic genetics. --- Polymerase chain reaction. --- Chain reaction, Polymerase --- PCR (Biochemistry) --- Polymerization --- DNA polymerases --- Forensic biology --- Genetics --- Medical jurisprudence --- Deoxyribonucleic acid synthesis --- Deoxyribonucleic acid --- Desoxyribonucleic acid --- Thymonucleic acid --- TNA (Nucleic acid) --- Deoxyribose --- Nucleic acids --- Genes --- DNA fingerprints --- DNA identification --- DNA profiles --- DNA profiling --- Genetic fingerprinting --- Genetic fingerprints --- Forensic genetics --- Identification --- Physiology. --- Synthesis. --- Technique

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"A decade ago we began working on the problem of analyzing psychotherapeutic interviews. As time passed and as solutions to our research problems emerged, we began to realize the solutions had general implications. Going from the specific to the general carries within it the danger of tunnel vision but sometimes has the advantage of conferring uniqueness of perspective. It also has the realistic advantage of being grounded in actual research problems. In our view a fundamental emphasis in the following essay is the insistence on faithful representation of subject behavior over periods of observation. This may be contrasted with the usual transformation of behavior to scores in which information is discarded and in which one draws the first step away from actuality. A second fundamental emphasis is on analyzing the representation of behavior with a minimum of assumptions. Although powerful and sophisticated mathematical techniques related to those discussed in this work exist, they seemed to us to require assumptions we were unwilling to make or to require analysis of but a fraction of the data. Thus the advantages of the use of distribution functions and of significance levels were, for us, offset and we were persuaded to follow our own path. As we proceeded in our search for a solution to our problems, the analysis of naturalistic data came to be viewed as a kind of factor analysis of behavior representations rather than of scores. These mathematical partitions may serve as a ground for hypothesis formation, psychological induction and further, more refined study. We conceive of the process of naturalistic observation and analysis as involving observation, the representation of the results of observation, analysis of the representation and the creation of a new framework for observation and further analysis culminating finally in rather formal hypotheses, theories and controlled experimentation. Methodologically our essay may be characterized as factor analytic or Thurstonian; logically, as Baconian; and procedurally as Darwinian or naturalistic. Although our use of the methods to be described has been limited to the analysis of psychotherapeutic interviews, we can envisage other uses by clinical and counseling psychologists, social psychologists, content analysts, comparative psychologists observing organisms in relatively free situations and, perhaps, taxonomists"--

Factor analysis.

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Intended as a companion to the Fundamentals of Forensic DNA Typing volume published in 2009, Advanced Topics in Forensic DNA Typing: Methodology contains 18 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field and citation to more than 2800 articles and internet resources. The book builds upon the previous two editions of John Butler's internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. This book provides the most detailed information written to-date on DNA databases, low-level DNA, validation, and numerous other topics including a new chapter on legal aspects of DNA testing to prepare scientists for expert witness testimony. Over half of the content is new compared to previous editions. A forthcoming companion volume will cover interpretation issues. Contains the latest information - hot-topics and new technologies Well edited, attractively laid out, and makes productive use of its four-color format Author John Butler is ranked as the number one "high-impact author in legal medicine and forensic science, 2001 to 2011" by ScienceWatch.com.

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