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Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine. .

Vaccines. --- Infectious diseases. --- Virology. --- Immunology. --- Human physiology. --- Vaccine. --- Infectious Diseases. --- Human Physiology. --- Human biology --- Medical sciences --- Physiology --- Human body --- Immunobiology --- Life sciences --- Serology --- Microbiology --- Biologicals --- Infectious & contagious diseases. --- Medical microbiology & virology.

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Immunology. Immunopathology --- Human physiology --- Medical microbiology, virology, parasitology --- Infectious diseases. Communicable diseases --- immunologie --- virologie --- besmettelijke ziekten --- fysiologie --- vaccinatie

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Proteins --- Peptides --- Bacteriophages --- Microbial biotechnology --- Affinity chromatography --- Viral proteins

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Roitt's Essential Immunology has established itself as the book of choice for students of immunology worldwide. This excellent textbook is commonly regarded as 'the best of the immunology primers' and the eleventh edition remains at the cutting edge of this fascinating area of science. The trademark of this book is its highly readable introduction to the subject, its emphasis on core knowledge and its excellent four-color artwork. The internationally renowned authors have extensively updated all aspects of the book to produce a new edition, which will be an invaluable resource to students of immunology and medicine. Roitt's Essential Immunology is supported by a website at www.roitt.com This useful on-line resource includes interactive multiple-choice questions with feedback, key concepts explained with animations, further reading lists with PubMed links, and an archive of images from the book.

Immunology. Immunopathology --- Immune System. --- Immunity. --- Disease --- Immunoglobulins --- Immune Systems --- System, Immune --- Systems, Immune --- immunology --- Immune Process --- Immune Response --- Immune Processes --- Immune Responses --- Process, Immune --- Response, Immune --- Immune System --- Immunity --- Immune System Diseases. --- Immune System Diseases --- Allergy and immunology --- Allergy and Immunology

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Immunology. Immunopathology --- Immune System --- Immunity --- Immunology. --- Disease --- Immunoglobulins --- Immune Systems --- System, Immune --- Systems, Immune --- Immunobiology --- Life sciences --- Serology --- immunology --- Immunité --- Système immunitaire --- Immunologie --- Immune System. --- Immunity. --- Immunité. --- Système immunitaire. --- Immunologie. --- Immune Process --- Immune Response --- Immune Processes --- Immune Responses --- Process, Immune --- Response, Immune --- Immunology