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Integration of metabolism with virulence in Candida albicans

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Fungal Genomics
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ISBN: 9783540308096 Year: 2006 Publisher: Berlin, Heidelberg Springer-Verlag Berlin Heidelberg

Fungal genomics
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ISBN: 1280461470 9786610461479 3540308091 354025594X 3642065007 Year: 2006 Publisher: Berlin ; London : Springer,

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Through the integration of bioinformatic, genetic, transcriptomic, proteomic, metabolomic, phenomic, and other massive datasets, genomics is revealing exciting new insights into fungal cell biology. This volume focuses on the impact that genomics is having upon our understanding of fungal biology, across a wide range of species, and others.


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Fungal Genomics
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ISBN: 9783540308096 Year: 2006 Publisher: Berlin, Heidelberg Springer-Verlag Berlin Heidelberg

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Mycology, the study of fungi, originated as a subdiscipline of botany and was a descr- tive discipline, largely neglected as an experimental science until the early years of this century. A seminal paper by Blakeslee in 1904 provided evidence for sel?ncompatib- ity, termed heterothallism , and stimulated interest in studies related to the control of sexual reproduction in fungi by mating-type speci?cities. Soon to follow was the demonstration that sexually reproducing fungi exhibit Mendelian inheritance and that it was possible to conduct formal genetic analysis with fungi. The names Burgeff, Kniep and Lindegren are all associated with this early period of fungal genetics research. These studies and the discovery of penicillin by Fleming, who shared a Nobel Prize in 1945, provided further impetus for experimental research with fungi. Thus began a period of interest in mutation induction and analysis of mutants for biochemical traits. Such fundamental research, conducted largely with Neurospora crassa,led to theone gene: one enzyme hypothesis and to a second Nobel Prize for fungal research awarded to Beadle and Tatum in 1958. Fundamental research in biochemical genetics was extended to other fungi, especially to Saccharomyces cerevisiae, and by the mid-1960s fungal systems were much favored for studies in eukaryotic molecular biology and were soon able to compete with bacterial systems in the molecular arena.


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Yeast Gene analysis
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Year: 1998 Publisher: San Diego London Boston Academic press

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The mycota : a comprehensive treatise on fungi as experimental systems for basic and applied research.
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ISBN: 9783540255949 Year: 2006 Publisher: Berlin : Springer-Verlag,

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Fungi --- Mycology --- Treatises --- Fungi --- Mycology --- Treatises


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Protein synthesis and targeting in Yeast : proceedings of the Nato Advanced Research Workshop ... held at Canterbury, Kent, U.K., 4-8 July 1992

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