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"Insights to Neuroimmune Biology, Second Edition discusses the systemic regulatory network, coordinating, organizing and interpreting the rapidly accumulating knowledge. The ultimate goal of this book is to help readers understand the function of higher organisms, including man, in their entire complexity. This publication provides assessments and interpretations of accumulated experimental evidence, enabling the scientific community to keep abreast of essential advancements of our knowledge in a quest for understanding of the biology of higher organisms."--

Neuroimmunology. --- Neuroimmunomodulation --- Immunology --- Neurosciences --- Nervous System Diseases --- Nervous System --- immunology

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Insights to Neuroimmune Biology, Second Edition discusses the systemic regulatory network, coordination, organization, and interpretation of the rapidly accumulating knowledge on the topic of neuroimmune biology, with an ultimate goal of helping readers understand the function of higher organisms, including man, in their entire complexity. This publication provides assessments and interpretations of accumulated experimental evidence, enabling the scientific community to keep abreast of essential advancements of existing knowledge as we search for greater understanding of the biology of higher organisms.

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Morphological and functional studies revealed a complex system of primary sensory neurons that parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative

Inflammation - Molecular aspects. --- Inflammation -- Molecular aspects. --- Inflammation - Pathophysiology. --- Inflammation -- Pathophysiology. --- Neurogenic Inflammation. --- Neuropeptides. --- Sensory neurons. --- Inflammation --- Sensory neurons --- Neuropeptides --- Neurogenic Inflammation --- Neurologic Manifestations --- Nervous System Diseases --- Pathologic Processes --- Pathological Conditions, Signs and Symptoms --- Diseases --- Pathology --- Medicine --- Health & Biological Sciences --- Molecular aspects --- Pathophysiology --- Symptoms and General Pathology --- Pathological Processes --- Processes, Pathologic --- Processes, Pathological --- Nervous System Disorders --- Neurological Disorders --- Neurologic Disorders --- Disease, Nervous System --- Diseases, Nervous System --- Disorder, Nervous System --- Disorder, Neurologic --- Disorder, Neurological --- Disorders, Nervous System --- Disorders, Neurologic --- Disorders, Neurological --- Nervous System Disease --- Nervous System Disorder --- Neurologic Disorder --- Neurological Disorder --- Neurology --- Focal Neurologic Deficits --- Manifestations, Neurologic --- Manifestations, Neurological --- Neurologic Dysfunction --- Neurologic Findings --- Neurologic Manifestation --- Neurologic Signs --- Neurologic Symptoms --- Neurological Manifestations --- Neurologic Deficits --- Neurologic Signs and Symptoms --- Deficit, Focal Neurologic --- Deficit, Neurologic --- Deficits, Focal Neurologic --- Deficits, Neurologic --- Dysfunction, Neurologic --- Dysfunctions, Neurologic --- Finding, Neurologic --- Findings, Neurologic --- Focal Neurologic Deficit --- Manifestation, Neurologic --- Manifestation, Neurological --- Neurologic Deficit --- Neurologic Deficit, Focal --- Neurologic Deficits, Focal --- Neurologic Dysfunctions --- Neurologic Finding --- Neurologic Sign --- Neurologic Symptom --- Neurological Manifestation --- Sign, Neurologic --- Signs, Neurologic --- Symptom, Neurologic --- Symptoms, Neurologic --- Nervous System --- Innate Inflammatory Response --- Inflammations --- Inflammatory Response, Innate --- Innate Inflammatory Responses --- Immunity, Innate --- Inflammation, Neurogenic --- Inflammations, Neurogenic --- Neurogenic Inflammations --- Neuroimmunomodulation --- Inflammatory process --- Anti-inflammatory agents --- Brain peptides --- Nerve tissue proteins --- Neurotransmitters --- Peptides --- Neurons --- Immune system --- Endocrine glands --- Aging

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The book summarises the current understanding of the Nervous -, Endocrine and Immune systems with emphasis on shared mediators and receptors and functional interaction. In addition to the fundamental physiological and pathophysiological mechanisms, which are presented in detail, some clinically relevant subjects are also presented, such as inflammation, asthma and allergy, autoimmune disease, immunodeficiency and the acute phase response. A comprehensive presentation of neuroimmune biology Introduces the subject matter to the uninformed reader Contains basic informatio

Neuroimmunology --- Neuroendocrinology --- History.

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A new scientific discipline, acknowledged 65 years after its discovery, was the focus of the first Conference on Neuroimmune Biology in Canada. The papers presented at the conference, and in this volume, are dedicated to Dr. Hans Selye who is recognized as discovering the existence of a hypothalamic-pituitary-adrenal-thymus axis. This axis plays an important role in the adaptation of higher animals and man to various physical, chemical, biological and emotional challenges. The conference and participants also honored Dr. Andor Szentivanyi whose opening paper, "Studies on the hypothalamic regulation of histamine synthesis", is contained in the introduction to this book. Dr. Szentivanyi has dedicated his long research career to the clarification of the role of the central nervous system in immune and inflammatory reactions, and his experimental results are presented here. With an ultimate goal to achieve a more thorough understanding of higher organisms in their entire complexity, this book, the first in the series presents a coordinated and integrated view of the growing body of knowledge rapidly accumulating in this area.

HEALTH & FITNESS/Diseases - 
HEALTH & FITNESS/Nervous System (incl. Brain) - 
Immune system/Pathophysiology - 
MEDICAL/Neurology - 
Neuroimmunology - 
Neuroimmunomodulation - 
Systemic lupus erythematosus/Pathophysiology