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Tailoring of biomolecules using protein engineering technology, and host cells culture techniques are among the most sophisticated and elegant achievements of modern applied life sciences in which the basic fundamentals biotechnology are applicable for the development and manufacturing of biologics and other related bio-molecules for a hurdle free life with good health. A majority of biologics derived from genetically modified host cells in the current market are bio-formulation such as antibodies, nucleic acid products and vaccines. Such bio-formulations are developed mainly in two steps i.e. upstream process and downstream process. The first volume of this series begins with the latest information on how the classical stepwise host cells culture (mammals, animals, plants, and bacteria) methodology has been changed to fully continuous or partially continuous host cells culture process in order to economise the biopharmaceutical products manufacturing process. In addition this volume narrates a brief history on conceptual development of new thoughts in designing biotechnology industries for commercial production of variety of therapeutic proteins with structural modification on the basis of clinical requirements. The readers will feel exited by going through the latest discovery and development in applied life sciences for designing innovative biomolecules for health care with utmost safe. The most interesting part of this volume is newly developed concept on bioprinting. It explains how to design and fabricate animate objects by fusing or depositing material of interest in the form of powders, solid dusts, metal, liquid or even living cells or tissues by layers to produce 3D objectives. The first volume ends with the latest information on the current trend in biologics market, market dynamic, drives, and opportunities with challenges.
Nucleic acids. --- Systems biology. --- Biology—Technique. --- Nucleic Acid Chemistry. --- Systems Biology. --- Biological Techniques. --- Computational biology --- Bioinformatics --- Biological systems --- Molecular biology --- Polynucleotides --- Biomolecules --- Biomolecules. --- Molecular biology. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Systems biology --- Biological molecules --- Molecules
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Conceptual Development of Industrial Biotechnology for Commercial Production of Biopharmaceuticals and Vaccines provides insights on how to bring sustainability into biologic drug production. The cumulative facts and figures within in the book are helpful to promoters in monitoring value chain transfer process of super quality biologics for better return in profits. In addition, this is a useful reference for students, researchers and scientists in biotechnology, pharmaceutical science, medical sciences, and the R&D division of biotechnology-based industries. Conceptual development of biotechnology has taken new avenues with the integration of medical sciences, physical science, and engineering, hence this is a timely source. The current global market for vaccines, especially COVID-19, is tremendous. Bivalent oral polio vaccine, diphtheria, tetanus-containing, and measles-containing vaccines have a high demand internationally and recombinant DNA technology and protein engineering are helpful in the production of quality bio-products. Informs how biotechnology and pharmaceutical industries act as central pillars for the stable production of value-added biological drugs and vaccines from genetically engineered suitable vectors like microbe or cell lines from animals, mammals or plants. Highlights various traditional and modern techniques used for improvising the quality of suitable vectors to produce biologic drugs and vaccines under GMP manufacturing facilities. Provides updated information on the latest microchip-based bioreactors, disposable bag bioreactors, and animal systems as bioreactors to produce biologic drugs like Smart Biomolecules (next generation therapeutics), Bio-similar drugs, Bio-betters, and antibody-drug conjugates. Explains how the closed bioreactors with proper mechanical amendments are used for vaccine production.
Vaccines. --- Biologicals --- Biotechnology industries. --- Pharmaceutical biotechnology --- Automation. --- Biopharmaceutical technology --- Drugs --- Biotechnology --- Pharmaceutical technology --- Biomedical industries --- High technology industries --- Vaccines --- Drug Industry --- Biological Products --- Pharmaceutical Preparations --- Biotechnology. --- economics --- methods
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"Techniques for Downstream process for Biologic Drugs and Vaccines provides comprehensive technologies involved in processing postharvest broth to separate the target biological therapeutic products of extracellular or intercellular aspects in nature - to its highest purification form, and to thus make it acceptable to end users. The technologies involved in the post-harvesting of fermented broth are explained in this comprehensive resource in a simplified manner with different case studies to help non-engineering students and scientists easily capture the basic principle of biomass processing technologies and their applications in new projects related to the development and manufacturing of therapeutic bio-products. As conceptual development of biotechnology has taken new shape and style with the integration of medical sciences, physical science, and engineering, and has thus begun the need for the development of microbial or cell line process technology and application for large-scale isolation and purification of metabolites or vaccines through the fermentation process, this book covers the most important aspects." --
Biological products --- Therapeutic use. --- Pharmaceutical biotechnology. --- Biotherapy --- Vaccines --- Biotechnology. --- Biological Products --- isolation & purification
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Biological Products. --- Drug Discovery. --- Drug Development
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This book discusses the generation of green energy, providing fundamental scientific information on the availability of sustainable biological resources. It addresses inter- and multidisciplinary topics, including policies and strategies for sustainable energy; the environment and advanced renewable energy technology; electricity generation through solid waste management; and direct electricity generation using microbial fuel cells. It examines the application of the principles and quantitative relationships that define the process – as an effective technique to teach applied aspects of biomass energy technology conversion. In addition, it describes the latest commercialisation of microbial fuel cell technologies, bio-diesel production from microalgae, fermentation technology based on biobutanol from bacteria, and direct ethanol production from microalgae with attractive illustrations and models developed by corporate sectors.
Biomass energy. --- Renewable energy sources. --- Waste disposal. --- Microbiology. --- Sustainable development. --- Energy security. --- Renewable and Green Energy. --- Waste Management/Waste Technology. --- Applied Microbiology. --- Sustainable Development. --- Energy Security. --- Energy dependence --- Energy independence --- Energy insecurity --- Security, Energy --- Energy policy --- Development, Sustainable --- Ecologically sustainable development --- Economic development, Sustainable --- Economic sustainability --- ESD (Ecologically sustainable development) --- Smart growth --- Sustainable development --- Sustainable economic development --- Economic development --- Microbial biology --- Biology --- Microorganisms --- Alternate energy sources --- Alternative energy sources --- Energy sources, Renewable --- Sustainable energy sources --- Power resources --- Renewable natural resources --- Agriculture and energy --- Environmental aspects --- Refuse and refuse disposal. --- Discarded materials --- Disposal of refuse --- Garbage --- Household waste --- Household wastes --- Refuse and refuse disposal --- Rubbish --- Solid waste management --- Trash --- Waste disposal --- Waste management --- Wastes, Household --- Sanitation --- Factory and trade waste --- Pollution --- Pollution control industry --- Salvage (Waste, etc.) --- Street cleaning --- Waste products --- Renewable energy resources. --- Waste management.
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Environmental management. --- Environmental stewardship --- Stewardship, Environmental --- Environmental sciences --- Management
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This book discusses the generation of green energy, providing fundamental scientific information on the availability of sustainable biological resources. It addresses inter- and multidisciplinary topics, including policies and strategies for sustainable energy; the environment and advanced renewable energy technology; electricity generation through solid waste management; and direct electricity generation using microbial fuel cells. It examines the application of the principles and quantitative relationships that define the process – as an effective technique to teach applied aspects of biomass energy technology conversion. In addition, it describes the latest commercialisation of microbial fuel cell technologies, bio-diesel production from microalgae, fermentation technology based on biobutanol from bacteria, and direct ethanol production from microalgae with attractive illustrations and models developed by corporate sectors.
General microbiology --- Medical microbiology, virology, parasitology --- Relation between energy and economics --- Water supply. Water treatment. Water pollution --- Environmental protection. Environmental technology --- Production management --- ethanol --- brandstofcellen --- biomassa --- toegepaste microbiologie --- energiemanagement (economie) --- algen --- hernieuwbare energie --- duurzaamheid --- bio-energie --- microalgen --- microbiologie --- waterverontreiniging --- afvalverwerking --- duurzame ontwikkeling --- afval --- dieselmotoren
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Environmental Technology and Sustainability: Physical, Chemical and Biological Technologies for Clean Environmental Management provides a dependable source of information on the fundamental scientific evidence involved in environmental protection and sustainable development. The book provides the basic natural sciences that underpin the understanding, development and application of environment technologies that support a clean inhabitable world that includes environmental technologies and sustainable, renewable energy systems. It considers the science and technology for environmental benefits, including the development of both smarter, cleaner technologies for environmental protection, conservation, and more.
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This book presents a concept for implementing a mass balance approach toward developing an effective eco-friendly, livestock farming system independent of external energy input. In this context it describes a modern, integrated farming system, and includes comprehensive technical information explaining the design and evaluation of manure management systems, and modeling and operational tools. It first discusses the mass balance operating process, highlighting the difference between imported and exported mass across the farm boundary. Estimating mass balance can provide critical information for (comprehensive) nutrient management planning and for managing the movement of nutrients and manure. It then explains the estimation of whole-farm P mass balance using a suitable model system. The subsequent chapters provide updated information on management aspects of livestock-farming and generation of multiple job opportunities, and also explore various aspects of livestock farming operational protocols like housing and management; nurture of rams, ewes and lambs, new born calves and heifers; care of buck, doe and kid- nutrition flushing; concept zero grazing-systems; disease control and management; integrated goat farming; and crop-livestock integration. Further, the book addresses crop-livestock integration; energy autonomy in cattle farming; value added biopharmaceuticals from cattle farming; CAPEX for cattle farming; concepts of cattle farming; detrimental effects of the industry; topographic and edaphic factors, and thermal stress on livestock growth and development; socioeconomic development; and water requirements for livestock. The book concludes with the most important issue in the field of agriculture and veterinary science: “Livestock Farming with Care,” describing sustainable, eco-friendly livestock farming by highlighting issues like animal feed vs. human food; agricultural GDP vs livestock, and factors affecting the sustainability of livestock farming. Given its scope, this book is a valuable resource for researchers and students alike, and will also appeal to practitioners in the field of livestock.
Animal anatomy. --- Animal physiology. --- Animal genetics. --- Animal welfare. --- Animal Anatomy / Morphology / Histology. --- Animal Physiology. --- Animal Genetics and Genomics. --- Animal Welfare/Animal Ethics. --- Abuse of animals --- Animal cruelty --- Animals --- Animals, Cruelty to --- Animals, Protection of --- Animals, Treatment of --- Cruelty to animals --- Humane treatment of animals --- Kindness to animals --- Mistreatment of animals --- Neglect of animals --- Prevention of cruelty to animals --- Protection of animals --- Treatment of animals --- Welfare, Animal --- Genetics --- Animal physiology --- Biology --- Anatomy --- Animal anatomy --- Physiology --- Abuse of --- Social aspects --- Livestock --- Farm management. --- Environmental aspects. --- Ecology. --- Farm organization --- Farms --- Agriculture --- Land tenure --- Management --- Agricultural landscape management --- Agricultural systems --- Animal husbandry --- Farm animals --- Live stock --- Stock (Animals) --- Stock and stock-breeding --- Animal culture --- Animal industry --- Domestic animals --- Food animals --- Herders --- Range management --- Rangelands --- Economic aspects
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