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This volume addresses oxidant-reduction or redox and antioxidant sensitive molecular mechanisms and how they are implicated in different disease processes. Possible strategies to pharmacologically and/or nutritionally manipulate such redox-sensitive molecular responses are emphasized.Key Features:* Reactive species as intracellular messengers* Redox regulation of cellular responses* Clinical implications of redox signaling and antioxidant therapy
Active oxygen in the body. --- Active oxygen --- Antioxidants --- Cellular signal transduction. --- Genetic regulation. --- Pathophysiology. --- Physiological effect. --- Gene expression --- Gene expression regulation --- Gene regulation --- Biosynthesis --- Cellular control mechanisms --- Molecular genetics --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Information theory in biology --- Chemical inhibitors --- Oxygen in the body --- Regulation
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This volume addresses oxidant-reduction or redox and antioxidant sensitive molecular mechanisms and how they are implicated in different disease processes. Possible strategies to pharmacologically and/or nutritionally manipulate such redox-sensitive molecular responses are emphasized. Key features: reactive species as intracellular messengers; redox regulation of cellular responses; and clinical implications of redox signaling and antioxidant therapy.
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