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United States. --- #KVHA:Recht; Verenigde Staten --- #KVHA:American Studies

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Strategic Defense Initiative.

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The focus of this book is the large-scale statistical behavior of solutions of divergence-form elliptic equations with random coefficients, which is closely related to the long-time asymptotics of reversible diffusions in random media and other basic models of statistical physics. Of particular interest is the quantification of the rate at which solutions converge to those of the limiting, homogenized equation in the regime of large scale separation, and the description of their fluctuations around this limit. This self-contained presentation gives a complete account of the essential ideas and fundamental results of this new theory of quantitative stochastic homogenization, including the latest research on the topic, and is supplemented with many new results. The book serves as an introduction to the subject for advanced graduate students and researchers working in partial differential equations, statistical physics, probability and related fields, as well as a comprehensive reference for experts in homogenization. Being the first text concerned primarily with stochastic (as opposed to periodic) homogenization and which focuses on quantitative results, its perspective and approach are entirely different from other books in the literature. .

Homogenization (Differential equations) --- Differential equations, Partial --- Differential equations, partial. --- Distribution (Probability theory. --- Mathematical optimization. --- Partial Differential Equations. --- Probability Theory and Stochastic Processes. --- Mathematical Physics. --- Calculus of Variations and Optimal Control; Optimization. --- Optimization (Mathematics) --- Optimization techniques --- Optimization theory --- Systems optimization --- Mathematical analysis --- Maxima and minima --- Operations research --- Simulation methods --- System analysis --- Distribution functions --- Frequency distribution --- Characteristic functions --- Probabilities --- Partial differential equations --- Partial differential equations. --- Probabilities. --- Mathematical physics. --- Calculus of variations. --- Isoperimetrical problems --- Variations, Calculus of --- Physical mathematics --- Physics --- Probability --- Statistical inference --- Combinations --- Mathematics --- Chance --- Least squares --- Mathematical statistics --- Risk

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"The machinery that controls how DNA is packaged and genes are activated plays an important role in cancer. This book examines the functions of components of this machinery, how they can be dysregulated, and the prospects for targeting them therapeutically. Highlights include: - PRC2 polycomb complex - Therapy- Lysine demethylase inhibitors - Epigenetic mechanisms of therapy resistance and tumor heterogeneity - Long non-coding RNA"--

Cancer --- Chromosome abnormalities. --- Mutation (Biology) --- Neoplasms --- Aberrations chromosomiques. --- Mutation (biologie) --- Genetic aspects. --- genetics. --- Génétique.