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Schwann cells are a diverse group of cells formed from neural crest cells. They are essential components of the peripheral nerves of both vertebrate and invertebrate nervous systems. The diversity of Schwann cell subsets and function is seen in those Schwann cells that form myelin - that uniquely specialised part of the plasma membrane that spirals around axonal lengths to myelinate the peripheral nerves. The Biology of Schwann Cells concentrates on the cells of mammals and in particular humans. It covers the distinction between compact and non-compact myelin in depth, along with the perisynaptic cells which form the partnership between nerve terminals and muscle fibre. Developmental aspects are discussed alongside differentiation, and the genetics of the cells in health and disease. With chapters from world-renowned experts, this book is aimed at postgraduates and researchers in neuroscience and neurology and anyone involved in the study of peripheral nerves.
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Traditionally, oligodendrocytes have been assumed to play a minor supporting role in the central nervous system and their importance has generally been overlooked. For the first time, this book provides a dedicated review of all of the major aspects of oligodendrocyte biology, including development, organization, genetics, and immunobiology. Later chapters emphasize the importance of this underestimated cell to the mammalian central nervous system by exploring the role of myelin synthesis and maintenance in neural disease and repair. Particular attention is paid to multiple sclerosis (MS), arguably the prime example of an acquired demyelinating disease, with detailed examinations of the current concepts regarding demyelination, oligodendroglial damage, and remyelination in MS lesions.
Neuroglia. --- Myelination. --- Myelin sheath formation --- Myelinization --- Myelinogenesis --- Demyelination --- Myelin sheath --- Glial cells --- Nerve tissue --- Nerves
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This 2006 book examines the exciting discoveries in the study of marsupials of the last 20 years. These discoveries have led to significant developments in our understanding of this unique group of mammals. The impact of these developments have been such that marsupials are coming to be seen as model organisms in studies of life history evolution, ageing and senescence, sex determination and the development and regeneration of the nervous system. This volume brings together information scattered throughout the primary literature. Coverage includes evolutionary history and management strategies as well as all aspects of basic biology. A complete listing of known species and a comprehensive list of references make this a unique repository of information on this fascinating group of animals.
Marsupiaux --- Mammifères --- Marsupials. --- 599.2 --- Buideldier --- Marsupialia. Pouched mammals --- 599.2 Marsupialia. Pouched mammals --- Marsupials --- Marsupialia --- Pouched animals --- Mammals --- Marsupiaux. --- Mammifères. --- Mammals. --- Eutheria --- Mammalia --- Mammalians --- Prototheria --- Theria --- Vertebrates
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