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It is with great pleasure we welcome you to the 10th ACM/SPEC International Conference on Performance Engineering (ICPE), and to the amazing city of Mumbai, India. Mumbai is a bustling metropolis of over 20 million people that is both the financial and the entertainment capital of India. It is a city of stark contrasts and not a conventional 'tourist's city'. A visitor can visit a large number of heritage buildings from the colonial era or the 6th century Elephanta Caves or the charming suburb of Bandra, with its Churches and sea-side promenades. ACM/SPEC ICPE 2019 will be held in the Victor Menezes Convention Centre, a five-floor convention centre with a 350+ capacity auditorium and comfortable seminar and conference rooms. The Centre is located within the campus of the Indian Institute of Technology, Bombay (IIT Bombay), situated in the suburb of Powai. In its 10th edition, ICPE is being held in Asia (India), which marks its first time outside Europe and America. This has given an important signal of both acknowledging the presence of a vibrant scientific community working in performance engineering in this part of the world, as well as a desire to increase this community's involvement with ICPE by bringing it geographically close to them. ICPE2019 continues its tradition of being the premier forum for the integration of theory and practice in the field of performance engineering, while founding its roots into the ACM Workshop on Software Performance (WOSP since 1998) and the SPEC International Performance Engineering Workshop (SIPEW since 2008). It brings together researchers and industry practitioners to share ideas, discuss challenges, and present results of both work-inprogress and state-of-the-art research on performance engineering of software and systems.

Computer systems --- Reliability --- Evaluation

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It is with great pleasure we welcome you to the 10th ACM/SPEC International Conference on Performance Engineering (ICPE), and to the amazing city of Mumbai, India. Mumbai is a bustling metropolis of over 20 million people that is both the financial and the entertainment capital of India. It is a city of stark contrasts and not a conventional 'tourist's city'. A visitor can visit a large number of heritage buildings from the colonial era or the 6th century Elephanta Caves or the charming suburb of Bandra, with its Churches and sea-side promenades. ACM/SPEC ICPE 2019 will be held in the Victor Menezes Convention Centre, a five-floor convention centre with a 350+ capacity auditorium and comfortable seminar and conference rooms. The Centre is located within the campus of the Indian Institute of Technology, Bombay (IIT Bombay), situated in the suburb of Powai. In its 10th edition, ICPE is being held in Asia (India), which marks its first time outside Europe and America. This has given an important signal of both acknowledging the presence of a vibrant scientific community working in performance engineering in this part of the world, as well as a desire to increase this community's involvement with ICPE by bringing it geographically close to them. ICPE2019 continues its tradition of being the premier forum for the integration of theory and practice in the field of performance engineering, while founding its roots into the ACM Workshop on Software Performance (WOSP since 1998) and the SPEC International Performance Engineering Workshop (SIPEW since 2008). It brings together researchers and industry practitioners to share ideas, discuss challenges, and present results of both work-inprogress and state-of-the-art research on performance engineering of software and systems.

Computer systems --- Software engineering --- Evaluation --- Reliability

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This volume provides a variety of methods used to analyze ADAMTS proteases and ADAMTS-like proteins, including their structure, substrate profile, tissue and cell distribution, post-translational modification and biological pathways. Chapters discuss genetic, cell biology, biochemical and proteomics techniques applicable to the analysis of all the members of the ADAMTS superfamily. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, ADAMTS Proteases: Methods and Protocols is a valuable tool for researchers to study both simple and sophisticated methodologies that are often difficult to locate in primary research literature. .

Biochemistry. --- Proteomics. --- Protein Science. --- Molecular biology --- Proteins --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Composition