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Parasitic, bacterial and viral agents continue to challenge the welfare of humans, livestock, wild life and plants worldwide. The public health impact and financial consequences of these diseases are particularly hard on the already overburdened economies of developing countries especially in the tropics. Many of these disease agents utilize insect hosts (vectors) to achieve their transmission to mammals. In the past, these diseases were largely controlled by insecticide-based vector reduction strategies. Now, many of these diseases have reemerged in the tropics, recolonizing their previous range, and expanding into new territories previously not considered to be endemic. Habitat change, irrigation practices, atmospheric and climate change, insecticide and drug resistance as well as increases in global tourism, human traffic and commercial activities, have driven the reemergence and spread of vector borne diseases. While these diseases can be controlled through interventions aimed at both their vertebrate and invertebrate hosts, no effective vaccines exist, and only limited therapeutic prospects are available for their control in mammalian hosts. Molecular technologies such as transgenesis, which is the subject of this book, stand to increase the toolbox and benefit disease management strategies.
Insect pests --- Insects as carriers of disease. --- Transgenic animals. --- Vector control --- Biological control. --- Biological control of vectors --- Animals --- Transgenic organisms --- Animal genetic engineering --- Medical entomology --- Arthropod vectors --- Biological control of insects --- Insects --- Biological control --- Control --- Genetic engineering. --- Medicine. --- Genetic Engineering. --- Biomedicine general. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Designed genetic change --- Engineering, Genetic --- Gene splicing --- Genetic intervention --- Genetic surgery --- Genetic recombination --- Biotechnology --- Biomedicine, general. --- Health Workforce
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Parasitic, bacterial and viral agents continue to challenge the welfare of humans, livestock, wild life and plants worldwide. The public health impact and financial consequences of these diseases are particularly hard on the already overburdened economies of developing countries especially in the tropics. Many of these disease agents utilize insect hosts (vectors) to achieve their transmission to mammals. In the past, these diseases were largely controlled by insecticide-based vector reduction strategies. Now, many of these diseases have reemerged in the tropics, recolonizing their previous range, and expanding into new territories previously not considered to be endemic. Habitat change, irrigation practices, atmospheric and climate change, insecticide and drug resistance as well as increases in global tourism, human traffic and commercial activities, have driven the reemergence and spread of vector borne diseases. While these diseases can be controlled through interventions aimed at both their vertebrate and invertebrate hosts, no effective vaccines exist, and only limited therapeutic prospects are available for their control in mammalian hosts. Molecular technologies such as transgenesis, which is the subject of this book, stand to increase the toolbox and benefit disease management strategies.
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Arthropods --- Animals as carriers of disease. --- Animal ecology. --- Arthropod vectors. --- Animals --- Zoology --- Ecology --- Carriers of disease --- Disease vectors --- Vectors of disease --- Communicable diseases --- Zoology, Medical --- Zoonoses --- Transmission --- Arthropoda as carriers of disease --- Invertebrates as carriers of disease
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This book describes the huge opportunity to modify insect phenotypes through genetic engineering to benefit human health and agriculture. Precise DNA modifications and gene drive approaches are much more focused with improved safety. The development of modelling, ethical considerations, public response and regulatory oversight is covered.
Transgenic animals --- Insects --- Insect cell biotechnology. --- Genetic engineering.
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