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It has only recently been appreciated that the immune and skeletal systems have major interactions. It is now well documented that osteoclasts, which are important cellular mediators of skeletal homeostasis, are derived from hematopoietic precursors that also give rise to immune cells. In addition, numerous cytokines that were first shown to regulate immune cell function have also been demonstrated to regulate bone cells and influence skeletal health. Conversely, products of bone cells appear critical for the engraftment of marrow in bone, the normal development of the hematopoietic and immune systems and provide niche for long-term memory B and T cells. In the past scientists involved in immune and bone cell investigations have rarely interacted in a significant way as these disciplines have developed independently and, for the most part, remain separate. The conference will bring together leading international scientists from both fields to interact so that new collaboration can develop and more rapid progress in understanding the relationships between these fields can be achieved. Short talks will be selected from abstracts from the international community. This conference will have a format to provide an environment of maximum interaction and interchange through lectures, posters, and open discussion.

Allergy and Immunology -- Congresses. --- Bone and Bones -- immunology -- Congresses. --- Immunology. --- Musculoskeletal Diseases -- immunology -- Congresses. --- Musculoskeletal System -- immunology -- Congresses. --- Musculoskeletal system. --- Immunology --- Musculoskeletal system --- Hematologic Diseases --- Skeleton --- Musculoskeletal Diseases --- Connective Tissue --- Publication Formats --- Connective Tissue Cells --- Macrophages --- Osteoclasts --- Bone Marrow Diseases --- Osteoblasts --- Congresses --- Bone and Bones --- Bone Diseases --- Myeloid Cells --- Cells --- Diseases --- Hemic and Lymphatic Diseases --- Tissues --- Musculoskeletal System --- Publication Characteristics --- Anatomy --- Biology --- Medicine --- Microbiology & Immunology --- Medical Research --- Health & Biological Sciences --- Locomotor system --- Musculo-skeletal system --- Skeletomuscular system --- Immunobiology --- Medicine. --- Pharmacology. --- Biotechnology. --- Infectious diseases. --- Pathology. --- Microbiology. --- Biomedicine. --- Infectious Diseases. --- Pharmacology/Toxicology. --- Life sciences --- Serology --- Microbial biology --- Microorganisms --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive --- Chemical engineering --- Genetic engineering --- Drug effects --- Medical pharmacology --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Clinical sciences --- Medical profession --- Human biology --- Pathology --- Physicians --- Physiological effect --- Emerging infectious diseases. --- Toxicology. --- Pharmacology --- Poisoning --- Poisons --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Toxicology

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Hurricanes are nature’s most destructive agents. They have recently been linked to changes in climate. A 4-day international summit on hurricanes and climate change took place in 2007 to discuss and debate various scientific issues related to this important topic. There were 77 attendees from 18 different countries who participated in the summit. This book is a sample collection of papers from talks that were presented. The chapters are organized around the broad hurricane-climate themes of empirical evidence, statistical methods, and numerical models. A major focus of the conference was the importance of statistical models for understanding how hurricane activity is changing and may change in the future. Emphasis was also placed on evidence of low-frequency swings in hurricane activity using historical and geological records. Results from various high-resolution numerical models, including a 20-km mesh model, were consistent in showing stronger hurricanes in a warmer future. Most numerical models indicate an overall decrease in the number of storms attributable to greater atmospheric stability and to a decrease in vertical mass flux. This book is unique in its scope drawing from an international community of scholars in the field of hurricane climate science. The science addresses a variety of perspectives ranging from the microphysics of lightning to geological evidence of prehistoric storminess.

Digital control systems --- Congresses. --- Digital control systems --Congresses. --- Hurricanes --- Cyclones --- Cyclonic storms --- Earth sciences. --- Meteorology. --- Oceanography. --- Geobiology. --- Atmospheric sciences. --- Ecotoxicology. --- Earth Sciences. --- Atmospheric Sciences. --- Biogeosciences. --- Climatic changes --- Global warming --- Environmental aspects --- Lows (Meteorology) --- Storms --- Changes, Climatic --- Climate change --- Climate changes --- Climate variations --- Climatic change --- Climatic fluctuations --- Climatic variations --- Global climate changes --- Global climatic changes --- Climatology --- Climate change mitigation --- Teleconnections (Climatology) --- Changes in climate --- Climate change science --- Environmental toxicology. --- Ecotoxicology --- Pollutants --- Pollution --- Environmental health --- Toxicology --- Oceanography, Physical --- Oceanology --- Physical oceanography --- Thalassography --- Earth sciences --- Marine sciences --- Ocean --- Biology --- Biosphere --- Aerology --- Atmospheric science --- Atmospheric sciences --- Atmosphere

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This volume presents a collection of reviews derived from work presented at the Aegean Conference: “3rd Crossroads between innate and adaptive immunity” which occurred during September 27 - October 2, 2009 at the Minoa Palace Conference Center in Chania, Crete, Greece. This meeting was the third in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity. The various facets of the innate response, including dendritic cells, T cells, B cells, NK cells, NK-T cells and the complement cascade during the host response to pathogens and tumors is only now starting to be elucidated.  The respective fields that focus on these immune cells and molecules have tended to be relatively compartmentalized, and yet emerging evidence points to the interconnectedness of these facets in coordinating the innate response, and its subsequent impact on the adaptive response.  The goal of this conference was to initiate cross-talk between these diverse immunological fields, and promote and facilitate discussion on the interactions between the innate immune response and the adaptive immune response and ultimately facilitate collaboration between these areas of study. Following on the footsteps of the outstanding success of its precursors, the  “3rd Crossroads between Innate and Adaptive Immunity” Aegean Conference was highly successful in bringing together and connecting scientists and experts from around the world to address critical areas of Innate and Adaptive immunity.

Immunity -- Congresses. --- Immunology -- Congresses. --- Natural immunity -- Congresses. --- Natural immunity --- Immune response --- Lymphocytes --- Biological Science Disciplines --- Diseases --- Immune System Phenomena --- Publication Formats --- Adaptive Immunity --- Natural Science Disciplines --- Phenomena and Processes --- Publication Characteristics --- Leukocytes, Mononuclear --- Leukocytes --- Disciplines and Occupations --- Immune System --- Blood Cells --- Blood --- Cells --- Hemic and Immune Systems --- Anatomy --- T-Lymphocytes --- Immunity, Innate --- Congresses --- Physiology --- Immunity, Active --- Immunity --- Neoplasms --- Medicine --- Biology --- Health & Biological Sciences --- Medical Research --- Microbiology & Immunology --- Regulation --- Disease resistance --- Host resistance --- Innate immunity --- Innate resistance --- Native immunity --- Natural resistance --- Nonspecific immunity --- Resistance to disease --- Medicine. --- Immunology. --- Pharmacology. --- Infectious diseases. --- Biochemistry. --- Microbiology. --- Biomedicine. --- Infectious Diseases. --- Pharmacology/Toxicology. --- Biochemistry, general. --- Microbial biology --- Microorganisms --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Drug effects --- Medical pharmacology --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Immunobiology --- Life sciences --- Serology --- Clinical sciences --- Medical profession --- Human biology --- Pathology --- Physicians --- Composition --- Physiological effect --- Emerging infectious diseases. --- Toxicology. --- Pharmacology --- Poisoning --- Poisons --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Toxicology