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The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means “above” genetics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures. Each of these topics will be covered in this book.

Behavior genetics. --- Epigenesis, Genetic. --- Epigenetics. --- Medicine. --- Carcinogenesis --- Epigenetics --- Biology --- Neoplastic Processes --- Diseases --- Gene Expression Regulation --- Pathologic Processes --- Biological Science Disciplines --- Genetic Processes --- Natural Science Disciplines --- Genetic Phenomena --- Pathological Conditions, Signs and Symptoms --- Disciplines and Occupations --- Phenomena and Processes --- Neoplasms --- Epigenesis, Genetic --- Genetics --- Cell Transformation, Neoplastic --- Medicine --- Health & Biological Sciences --- Oncology --- Medical Research --- Molecular aspects --- Carcinogenesis. --- Cancer --- Oncogenesis --- Pathogenesis of cancer --- Tumorigenesis --- Pathogenesis --- Cancer research. --- Human genetics. --- Oncology. --- Biomedicine. --- Cancer Research. --- Human Genetics. --- Tumors --- Heredity, Human --- Human biology --- Physical anthropology --- Cancer research --- Clinical sciences --- Medical profession --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Genetic toxicology --- Oncology  . --- Molecular aspects. --- genetics --- Epigenetic Process --- Epigenetics Processes --- Epigenetic Processes --- Genetic Epigenesis --- Process, Epigenetic --- Processes, Epigenetic --- Processes, Epigenetics --- Epigenome --- DNA Methylation --- Neoplastic Cell Transformation --- Transformation, Neoplastic Cell --- Tumorigenic Transformation --- Neoplastic Transformation, Cell --- Cell Neoplastic Transformation --- Cell Neoplastic Transformations --- Cell Transformations, Neoplastic --- Neoplastic Cell Transformations --- Neoplastic Transformations, Cell --- Transformation, Cell Neoplastic --- Transformation, Tumorigenic --- Transformations, Cell Neoplastic --- Transformations, Neoplastic Cell --- Transformations, Tumorigenic --- Tumorigenic Transformations --- Cell Line, Transformed --- Molecular carcinogenesis --- Pathology, Molecular

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Hydraulic fracturing is a technique used to recover oil and natural gas from underground low permeability rock formations. Hydraulic fracturing involves pumping fluids (primarily water and a small portion of chemicals, along with sand or other proppant) under high pressure into rock formations to crack them and allow the resources inside to flow to a production well. The technique has been the subject of controversy because of the potential effects that hydraulic fracturing and related oil and gas production activities may have on the environment and health. This book focuses on selected legal

Hydraulic fracturing --- Fracking (Engineering) --- Fracturing, Hydraulic --- Hydrofracking --- Hydraulic engineering --- Rock mechanics --- Law and legislation --- Environmental aspects