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Volume 323 of Methods in Enzymology is dedicated to the energetics of biological macromolecules. Understanding the molecular mechanisms underlying a biological process requires detailed knowledge of the structural relationships within the system and an equally detailed understanding of the energetic driving forces that control the structural interactions. This volume presents modern thermodynamic techniques currently being utilized to study the energetic driving forces in biological systems. It will be a useful reference source and textbook for scientists and students whose goal

Bio-energetica --- Bioenergetics --- Biological molecules --- Biologische moleculen --- Biomoleculen --- Biomolecules --- Biomolécules --- Bioénergétique --- Dynamica [Thermo] --- Dynamique [Thermo] --- Energetica [Bio-] --- Energie biologique --- Energy [Biological ] --- Energy balance (Biology) --- Energy budget (Biology) --- Energy dynamics (Ecology) --- Energy utilization (Biology) --- Macromoleculen --- Macromolecules --- Macromolécules --- Moleculen [Bio] --- Moleculen [Biologische ] --- Moleculen [Macro] --- Molecules [Biological ] --- Molécules [Macro] --- Molécules biologiques --- Thermodynamica --- Thermodynamics --- Thermodynamique --- Allosteric regulation. --- Bioenergetics. --- Energy Metabolism. --- Macromolecular Systems. --- Macromolecules. --- Molecular Conformation. --- Thermodynamics. --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Chemistry, Physical and theoretical --- Dynamics --- Mechanics --- Physics --- Heat --- Heat-engines --- Quantum theory --- Biochemistry --- Energy budget (Geophysics) --- Molecules --- Supramolecular chemistry --- Enzymology --- Macromolecular Systems --- Allosteric Regulation. --- Macromolécules --- Bioénergétique --- Molecular biology --- ENERGY METABOLISM --- MOLECULAR ASSOCIATION --- PROTEINS --- THERMODYNAMICS --- CONFORMATION --- REACTIONS

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The use of thermodynamics in biological research can be equated to an energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the sources of energy that drive the function? Which of the pathways are of biological significance? As the base of macromolecular structures continues to expand through powerful techniques of molecular biology, such as X-ray crystal data and spectroscopy methods, the importance of tested and reliable methods for answering these questions

Biochemistry -- Periodicals. --- Enzymes -- Periodicals. --- Enzymes. --- Thermodynamics. --- Human Anatomy & Physiology --- Animal Biochemistry --- Health & Biological Sciences --- Biophysics. --- Biological physics --- Biology --- Medical sciences --- Physics --- Chemistry, Physical and theoretical --- Dynamics --- Mechanics --- Heat --- Heat-engines --- Quantum theory

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In the past several years, there has been an explosion in the ability of biologists, molecular biologists and biochemists to collect vast amounts of data on their systems. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions. The use of thermodynamics in biological research is used as an "energy book-keeping system.? While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the

Thermodynamics. --- Metabolism --- Biophysical Processes --- Biochemical Processes --- Models, Theoretical --- Biological Science Disciplines --- Physical Phenomena --- Molecular Probe Techniques --- Chemistry --- Biochemistry --- Protein Folding --- Protein Binding --- Protein Interaction Mapping --- Thermodynamics --- Models, Molecular --- Biochemical Phenomena --- Natural Science Disciplines --- Physical Processes --- Chemical Processes --- Metabolic Phenomena --- Investigative Techniques --- Biophysical Phenomena --- Phenomena and Processes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Disciplines and Occupations --- Chemical Phenomena --- Human Anatomy & Physiology --- Animal Biochemistry --- Health & Biological Sciences --- Protein binding. --- Protein-protein interactions. --- Interactions, Protein-protein --- Protein interactions --- Binding, Protein --- Molecular association --- Allosteric proteins --- Radioligand assay --- Chemistry, Physical and theoretical --- Dynamics --- Mechanics --- Physics --- Heat --- Heat-engines --- Quantum theory --- PPIs (Protein-protein interactions) --- Interactomes

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