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Acute inflammation is a highly regulated process, and its dysregulation can lead to the development of a chronic inflammatory state which is believed to play a main role in the pathogenesis of many diseases, including cancer. In recent years, the need to find new anti-inflammatory molecules has raised the scientific community´s interest for marine natural products. In this regard, the marine environment represents a source for isolating a wealth of bioactive compounds. In this Special Issue, the reported products have been obtained from microalgae, sea cucumber, octopus, squid, red alga-derived fungus, cnidarians, hard-shelled mussel, and sponges.
Tropical Eastern Pacific --- Zoanthus pulchellus --- critical illness --- zoanthamine --- SPR analysis --- dendritic cells --- endothelial cell death --- T cell differentiation --- seafood waste --- microalgae --- pyrogallol-phloroglucinol-6 --- NRLP3 --- THP-1 macrophages --- fucoxanthin --- photo-protection --- cytokine --- thromboxane --- Isochrysis galbana --- fish oil --- photoprotection --- functional ingredients --- rosmarinic acid --- MAPK --- marine invertebrates --- poor blood circulation --- anti-inflammatory activity --- eicosapentaenoic acid --- anti-oxidative --- macroalgae --- colon inflammation --- MGDG --- TLR4 --- 6-bieckol --- polyunsaturated fatty acid --- matrix metalloproteinases-9 (MMP-9) --- acute sickness behavior --- UVB --- eicosanoid --- clavulones --- carotenoids --- denervation --- polyunsaturated fatty acids --- skin --- epidermal hyperplasia --- Geodia barretti --- omega-3 --- parenteral nutrition --- inflammation --- ultraviolet B --- docosahexaenoic acid --- signal transducer and activator of transcription 3 (STAT3) --- anti-inflammatory --- zoantharia --- vascular smooth muscle cell proliferation and migration --- bioactive molecules --- polysaccharides --- lipopolysaccharide (LPS) --- glycolipids --- DSS colitis --- punaglandins --- marine nutraceuticals --- marine vertebrates --- phlorotannins --- acute lung injury (ALI) --- NF-?B --- diatoms --- interleukin (IL) --- inflammasome --- Frondanol --- Cucumaria frondosa --- prostaglandins --- Ecklonia cava --- 6-bromoindole --- NO inhibition --- surgery
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This Special Issue covers both the in vitro and in vivo evaluation of marine carotenoids with anti-inflammatory and anticancer activities as well as clinical trials conducted in humans. Among the properties of carotenoids discussed in this book, it is worth highlighting the potential of astaxanthin and its precursor metabolite, adonixanthin, since oral administration of these carotenoids has shown beneficial effects on glioblastoma for the first time by suppressing cell proliferation and migration. In addition, astaxanthin has been shown to inhibit Helicobacter pylori-induced gastric carcinoma cell motility and, consequently, cancer progression through the inhibition of cytoskeleton reorganization. In addition, a carotenoid-containing lipid extract of Gloeothece sp. has demonstrated antioxidant, anti-inflammatory, and anticancer properties in vitro.
Medicine --- Helicobacter pylori --- gastric carcinoma --- astaxanthin --- cell motility --- cell migration --- bioavailability --- carotenoids --- marine --- nanoformulation --- oxidative stress --- reactive oxygen species --- brain --- cancer --- oral administration --- paracoccsu carotinifaciens --- xanthophyll carotenoid --- photodamage --- skin cancer --- photoaging --- marine carotenoids --- fucoxanthin --- xanthophylls --- natural compounds --- algae --- bioactive --- health --- neuroprotective agent --- neuroinflammation --- neurological diseases --- microalgae --- inflammation --- breast cancer --- bacterioruberin --- antioxidant --- pro-oxidant --- lutein --- β-carotene --- linolenic acid --- linoleic acid --- lipidic compounds --- PUFAs
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This Special Issue covers both the in vitro and in vivo evaluation of marine carotenoids with anti-inflammatory and anticancer activities as well as clinical trials conducted in humans. Among the properties of carotenoids discussed in this book, it is worth highlighting the potential of astaxanthin and its precursor metabolite, adonixanthin, since oral administration of these carotenoids has shown beneficial effects on glioblastoma for the first time by suppressing cell proliferation and migration. In addition, astaxanthin has been shown to inhibit Helicobacter pylori-induced gastric carcinoma cell motility and, consequently, cancer progression through the inhibition of cytoskeleton reorganization. In addition, a carotenoid-containing lipid extract of Gloeothece sp. has demonstrated antioxidant, anti-inflammatory, and anticancer properties in vitro.
Helicobacter pylori --- gastric carcinoma --- astaxanthin --- cell motility --- cell migration --- bioavailability --- carotenoids --- marine --- nanoformulation --- oxidative stress --- reactive oxygen species --- brain --- cancer --- oral administration --- paracoccsu carotinifaciens --- xanthophyll carotenoid --- photodamage --- skin cancer --- photoaging --- marine carotenoids --- fucoxanthin --- xanthophylls --- natural compounds --- algae --- bioactive --- health --- neuroprotective agent --- neuroinflammation --- neurological diseases --- microalgae --- inflammation --- breast cancer --- bacterioruberin --- antioxidant --- pro-oxidant --- lutein --- β-carotene --- linolenic acid --- linoleic acid --- lipidic compounds --- PUFAs
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This Special Issue covers both the in vitro and in vivo evaluation of marine carotenoids with anti-inflammatory and anticancer activities as well as clinical trials conducted in humans. Among the properties of carotenoids discussed in this book, it is worth highlighting the potential of astaxanthin and its precursor metabolite, adonixanthin, since oral administration of these carotenoids has shown beneficial effects on glioblastoma for the first time by suppressing cell proliferation and migration. In addition, astaxanthin has been shown to inhibit Helicobacter pylori-induced gastric carcinoma cell motility and, consequently, cancer progression through the inhibition of cytoskeleton reorganization. In addition, a carotenoid-containing lipid extract of Gloeothece sp. has demonstrated antioxidant, anti-inflammatory, and anticancer properties in vitro.
Medicine --- Helicobacter pylori --- gastric carcinoma --- astaxanthin --- cell motility --- cell migration --- bioavailability --- carotenoids --- marine --- nanoformulation --- oxidative stress --- reactive oxygen species --- brain --- cancer --- oral administration --- paracoccsu carotinifaciens --- xanthophyll carotenoid --- photodamage --- skin cancer --- photoaging --- marine carotenoids --- fucoxanthin --- xanthophylls --- natural compounds --- algae --- bioactive --- health --- neuroprotective agent --- neuroinflammation --- neurological diseases --- microalgae --- inflammation --- breast cancer --- bacterioruberin --- antioxidant --- pro-oxidant --- lutein --- β-carotene --- linolenic acid --- linoleic acid --- lipidic compounds --- PUFAs --- Helicobacter pylori --- gastric carcinoma --- astaxanthin --- cell motility --- cell migration --- bioavailability --- carotenoids --- marine --- nanoformulation --- oxidative stress --- reactive oxygen species --- brain --- cancer --- oral administration --- paracoccsu carotinifaciens --- xanthophyll carotenoid --- photodamage --- skin cancer --- photoaging --- marine carotenoids --- fucoxanthin --- xanthophylls --- natural compounds --- algae --- bioactive --- health --- neuroprotective agent --- neuroinflammation --- neurological diseases --- microalgae --- inflammation --- breast cancer --- bacterioruberin --- antioxidant --- pro-oxidant --- lutein --- β-carotene --- linolenic acid --- linoleic acid --- lipidic compounds --- PUFAs
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