Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Adverse drug reactions are one of the major constraints when using drugs. These adverse reactions can impact healthcare systems as strongly as many prevalent diseases. Identifying DNA variants associated with adverse drug reactions can help personalize medicine and sustain healthcare systems. This book delves into new advances in pharmacogenetics of cardiovascular, cancer, and nervous system drugs. It may be useful for clinicians and patients to understand the basics of pharmacogenetics.

5-fluorouracil --- capecitabine --- fluoropyrimidine --- thymidylate synthase --- thymidylate synthase enhancer region --- upstream stimulatory factor 1 --- adverse drug reactions --- pharmacogenomics --- epistasis --- random forest --- statin --- cardiovascular disease --- colorectal cancer --- personalised medicine --- toxicity --- (es)citalopram --- drug-gene-interaction --- drug-drug-interaction --- drug-drug-gene-interaction --- the PharmLines initiative --- antipsychotic agents --- pharmacogenetics --- cytochrome P-450 enzyme system --- psychotic disorders --- precision medicine --- direct oral anticoagulants --- clinical implementation --- atorvastatin --- SLCO1B1 --- HLA --- cutaneous adverse drug reaction --- SCAR --- genetic polymorphism --- antiepileptics --- CYP450 enzymes --- platelet reactivity --- single-nucleotide variants --- acute coronary syndrome --- clopidogrel --- genotype --- allele --- polymorphism --- HLA B --- CYP2C9*3 --- cutaneous adverse drug reactions (CADRs) --- anti-epileptic drugs (AEDS) --- phenytoin (PHT) --- genetic risk factors --- South India --- India --- cardiology --- adverse events --- guidelines --- n/a

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Emotional, behavioral, and neuropsychiatric conditions are common in individuals with intellectual disabilities (IDs), most notably epilepsy, aggression, self-injurious behaviors, and bipolar and other mood disorders. Despite the prevalence of such problems, there is a scarcity in the literature of reliable information on medical treatments for those with IDs. A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities provides a detailed framework for prescribing for this challenging population. Featuring the most up-to-date information on factors that inform prescribing, the Guide addresses basic issues and controversies (e.g., the rift between evidence-based and personalized medicine) in treating adults with cognitive deficits. Clients' specific needs are emphasized in developing appropriate and effective pharmacological intervention for improved outcomes and quality of life. Drugs discussed in the Guide include carbamazepine, clonazepam, diazepam, ethosuximide, felbamate, gabapentin, lacosamide, lamotrigine, levetiracetam, lithium, lorazepam, oxcarbazepine, phenobarbital, phenytoin, pregabalin, primidone, rufinamide,  tiagabine, topiramate, valproate, and zonisamide. For each of these compounds, the guidelines cover: Indications for use; relative and absolute contraindications. Assessment during treatment; therapeutic drug monitoring; warning signs and symptoms for caretakers. Dosage: administration; initial and maximum recommended dosage; modifications associated with drug-drug interactions, personal characteristics, and (where appropriate) genetic variations. Adverse drug reactions: common, relatively uncommon, and potentially lethal, plus risk of metabolic syndrome. Guidelines for discontinuation. References, tables, and drug utilization reviews. A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities is an indispensable decision-making reference for psychiatrists, neuropsychologists, psychopharmacologists, neurologists, internists, and clinical psychologists.

Anticonvulsants. --- Drug prescriptions. --- Psychotropic drugs. --- Psychotropic Drugs --- Central Nervous System Agents --- Central Nervous System Depressants --- Age Groups --- Disabled Persons --- Physiological Effects of Drugs --- Persons --- Therapeutic Uses --- Pharmacologic Actions --- Named Groups --- Chemical Actions and Uses --- Chemicals and Drugs --- Tranquilizing Agents --- Mentally Disabled Persons --- Adult --- Anticonvulsants --- Psychiatry --- Health & Biological Sciences --- Psychopharmacotherapy --- Affective disorders. --- Mental retardation. --- Drugs --- Prescribing --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Idiocy --- Intellectual disabilities --- Mental deficiency --- Retardation, Mental --- Disorders, Affective --- Mood disorders --- Anti-epileptic drugs --- Anticonvulsant drugs --- Antiepileptic agents --- Antiepileptics --- Intellectual disability. --- Medicine. --- Internal medicine. --- Neurology. --- Psychiatry. --- Psychopharmacology. --- Clinical psychology. --- Neuropsychology. --- Medicine & Public Health. --- Internal Medicine. --- Clinical Psychology. --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacology --- Pharmacy --- Mental retardation --- Developmental disabilities --- Psychology, Pathological --- People with mental disabilities --- Central nervous system depressants --- Muscle relaxants --- Convulsions --- Psychology, clinical. --- Medicine, Internal --- Medicine --- Nervous system --- Neuropsychiatry --- Medicine and psychology --- Mental health --- Behavioral pharmacology --- Psychotropic drugs --- Diseases --- Psychotropic effects --- Neurology . --- Psychology, Applied --- Psychological tests --- Neurophysiology --- Psychophysiology

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Anticonvulsants --- Carbamazepine --- Convulsions --- Epilepsy --- Seizures. --- Atonic Absence Seizures --- Atonic Seizures --- Clonic Seizures --- Complex Partial Seizures --- Convulsion, Non-Epileptic --- Generalized Absence Seizures --- Myoclonic Seizures --- Non-Epileptic Seizures --- Nonepileptic Seizures --- Partial Seizures --- Petit Mal Convulsion --- Seizures, Auditory --- Seizures, Clonic --- Seizures, Epileptic --- Seizures, Gustatory --- Seizures, Olfactory --- Seizures, Somatosensory --- Seizures, Tonic --- Seizures, Tonic-Clonic --- Seizures, Vertiginous --- Seizures, Vestibular --- Seizures, Visual --- Single Seizure --- Tonic Seizures --- Tonic-Clonic Seizures --- Absence Seizure --- Absence Seizures --- Atonic Absence Seizure --- Atonic Seizure --- Clonic Seizure --- Complex Partial Seizure --- Convulsion --- Convulsive Seizure --- Convulsive Seizures --- Epileptic Seizure --- Epileptic Seizures --- Generalized Absence Seizure --- Generalized Tonic-Clonic Seizures --- Jacksonian Seizure --- Myoclonic Seizure --- Non-Epileptic Seizure --- Nonepileptic Seizure --- Partial Seizure --- Seizure --- Seizures, Convulsive --- Seizures, Focal --- Seizures, Generalized --- Seizures, Motor --- Seizures, Sensory --- Tonic Clonic Seizure --- Tonic Seizure --- Tonic-Clonic Seizure --- Absence Seizure, Atonic --- Absence Seizure, Generalized --- Absence Seizures, Atonic --- Absence Seizures, Generalized --- Auditory Seizure --- Auditory Seizures --- Clonic Seizure, Tonic --- Clonic Seizures, Tonic --- Convulsion, Non Epileptic --- Convulsion, Petit Mal --- Convulsions, Non-Epileptic --- Focal Seizure --- Focal Seizures --- Generalized Seizure --- Generalized Seizures --- Generalized Tonic Clonic Seizures --- Generalized Tonic-Clonic Seizure --- Gustatory Seizure --- Gustatory Seizures --- Motor Seizure --- Motor Seizures --- Non Epileptic Seizure --- Non Epileptic Seizures --- Non-Epileptic Convulsion --- Non-Epileptic Convulsions --- Olfactory Seizure --- Olfactory Seizures --- Partial Seizure, Complex --- Partial Seizures, Complex --- Seizure, Absence --- Seizure, Atonic --- Seizure, Atonic Absence --- Seizure, Auditory --- Seizure, Clonic --- Seizure, Complex Partial --- Seizure, Convulsive --- Seizure, Epileptic --- Seizure, Focal --- Seizure, Generalized --- Seizure, Generalized Absence --- Seizure, Generalized Tonic-Clonic --- Seizure, Gustatory --- Seizure, Jacksonian --- Seizure, Motor --- Seizure, Myoclonic --- Seizure, Non-Epileptic --- Seizure, Nonepileptic --- Seizure, Olfactory --- Seizure, Partial --- Seizure, Sensory --- Seizure, Single --- Seizure, Somatosensory --- Seizure, Tonic --- Seizure, Tonic Clonic --- Seizure, Tonic-Clonic --- Seizure, Vertiginous --- Seizure, Vestibular --- Seizure, Visual --- Seizures, Generalized Tonic-Clonic --- Seizures, Nonepileptic --- Sensory Seizure --- Sensory Seizures --- Single Seizures --- Somatosensory Seizure --- Somatosensory Seizures --- Tonic Clonic Seizures --- Tonic-Clonic Seizure, Generalized --- Tonic-Clonic Seizures, Generalized --- Vertiginous Seizure --- Vertiginous Seizures --- Vestibular Seizure --- Vestibular Seizures --- Visual Seizure --- Visual Seizures --- Convulsants --- Eclampsia --- Kindling, Neurologic --- Convulsive disorders --- Convulsive seizures --- Nervous system --- Spasms --- Dibenzazepinecarboxamide --- Amides --- Anti-epileptic drugs --- Anticonvulsant drugs --- Antiepileptic agents --- Antiepileptics --- Central nervous system depressants --- Muscle relaxants --- Congresses --- Diseases --- Chemotherapy --- Neuropathology --- Seizures