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Horticultural crop yield and quality depend on genotype, environmental conditions, and production management. In particular, adverse environmental conditions may greatly affect crop performance, reducing crop yield by 50%–70%. Abiotic stresses such as cold, heat, drought, flooding, salinity, nutrient deficiency, and ultraviolet radiation affect multiple physiological and biochemical mechanisms in plants as they attempt to cope with the stress conditions. However, different crop species can have different sensitivities or tolerances to specific abiotic stresses. Tolerant plants may activate different strategies to adapt to or avoid the negative effect of abiotic stresses. At the physiological level, photosynthetic activity and light-use efficiency of plants may be modulated to enhance tolerance against the stress. At the biochemical level, several antioxidant systems may be activated, and many enzymes may produce stress-related metabolites to help avoid cellular damage, including compounds such as proline, glycine betaine, and amino acids. Within each crop species there is a wide variability of tolerance to abiotic stresses, and some wild relatives may carry useful traits for enhancing the tolerance to abiotic stresses in their progeny through either traditional or biotechnological breeding. The research papers and reviews presented in this book provide an update of the scientific knowledge of crop interactions with abiotic stresses.

heat --- polyphenols --- stomatal conductance --- shelf-life --- transpiration productivity --- transcription --- ornamental plants --- cold --- green areas --- flowering --- agronomic tools --- gas exchange --- ornamental --- prolonged storage --- transpiration --- greenhouse production --- dormancy --- temperature --- irradiance --- chilling requirements --- qPCR --- phenolics --- lodging --- hypoxia --- salinity --- relative humidity --- signal transduction --- chlorophyll fluorescence --- leaf water saturation deficit --- solar radiation --- plant choice --- partial root zone drying --- drought --- electro-conductivity --- growth --- flavonoids --- transpiration efficiency --- cloning --- oxidative stress --- breeding

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Microfluidics and lab-on-a-chip have, in recent years, come to the forefront in diagnostics and detection. At point-of-care, in the emergency room, and at the hospital bed or GP clinic, lab-on-a-chip offers the potential to rapidly detect time-critical and life-threatening diseases such as sepsis and bacterial meningitis. Furthermore, portable and user-friendly diagnostic platforms can enable disease diagnostics and detection in resource-poor settings where centralised laboratory facilities may not be available. At point-of-use, microfluidics and lab-on-chip can be applied in the field to rapidly identify plant pathogens, thus reducing the need for damaging broad spectrum pesticides while also reducing food losses. Microfluidics can also be applied to the continuous monitoring of water quality and can support policy-makers and protection agencies in protecting the environment. Perhaps most excitingly, microfluidics also offers the potential to enable entirely new diagnostic tests that cannot be implemented using conventional laboratory tools. Examples of microfluidics at the frontier of new medical diagnostic tests include early detection of cancers through circulating tumour cells (CTCs) and highly sensitive genetic tests using droplet-based digital PCR.This Special Issue on “Advances in Microfluidics Technology for Diagnostics and Detection” aims to gather outstanding research and to carry out comprehensive coverage of all aspects related to microfluidics in diagnostics and detection.

Medicine --- biosensors --- LoaD platforms --- microfluidics --- centrifugal microfluidics --- PoC devices --- SARS-CoV-2 --- COVID-19 --- nano-qPCR --- ultra-sensitive --- viral RNA --- viral load --- detection --- LabDisk --- vector-borne diseases --- malaria --- arboviruses --- insecticide resistances --- mosquito monitoring --- SAW --- Pirani --- compact --- wireless --- vacuum --- sensing --- digital droplet polymerase chain reaction (ddPCR) --- multiplexing --- centrifugal step emulsification --- droplet stability --- droplet fluorescence evaluation --- nanoparticle --- lipoplex --- polyplex --- raspberry pi --- siRNA --- python --- n/a

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Microfluidics and lab-on-a-chip have, in recent years, come to the forefront in diagnostics and detection. At point-of-care, in the emergency room, and at the hospital bed or GP clinic, lab-on-a-chip offers the potential to rapidly detect time-critical and life-threatening diseases such as sepsis and bacterial meningitis. Furthermore, portable and user-friendly diagnostic platforms can enable disease diagnostics and detection in resource-poor settings where centralised laboratory facilities may not be available. At point-of-use, microfluidics and lab-on-chip can be applied in the field to rapidly identify plant pathogens, thus reducing the need for damaging broad spectrum pesticides while also reducing food losses. Microfluidics can also be applied to the continuous monitoring of water quality and can support policy-makers and protection agencies in protecting the environment. Perhaps most excitingly, microfluidics also offers the potential to enable entirely new diagnostic tests that cannot be implemented using conventional laboratory tools. Examples of microfluidics at the frontier of new medical diagnostic tests include early detection of cancers through circulating tumour cells (CTCs) and highly sensitive genetic tests using droplet-based digital PCR.This Special Issue on “Advances in Microfluidics Technology for Diagnostics and Detection” aims to gather outstanding research and to carry out comprehensive coverage of all aspects related to microfluidics in diagnostics and detection.

biosensors --- LoaD platforms --- microfluidics --- centrifugal microfluidics --- PoC devices --- SARS-CoV-2 --- COVID-19 --- nano-qPCR --- ultra-sensitive --- viral RNA --- viral load --- detection --- LabDisk --- vector-borne diseases --- malaria --- arboviruses --- insecticide resistances --- mosquito monitoring --- SAW --- Pirani --- compact --- wireless --- vacuum --- sensing --- digital droplet polymerase chain reaction (ddPCR) --- multiplexing --- centrifugal step emulsification --- droplet stability --- droplet fluorescence evaluation --- nanoparticle --- lipoplex --- polyplex --- raspberry pi --- siRNA --- python --- n/a

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This book is a collection of chapters around the theme of parasitology and zoonosis in bot war and peace and the impact of these fields on public health. Individual experts have contributed reviews, novel research, and case series within the field to make a broad and interesting collection designed to stimulate thought and discussion in this area. The collection is dedicated to the life and career of Emeritus Professor John Marsden Goldsmid, an eminent parasitologist and advocate for further attention to these above listed fields of medicine. It would be suitable for medical and veterinary practitioners, students, scientists, and epidemiologists with an interest in parasitology and public health.

Medicine --- Epidemiology & medical statistics --- Ternidens --- ternidensiasis --- false hookworm --- hookworm --- soil transmitted helminths --- STH --- helminth --- zoonosis --- human --- primate --- leishmaniasis --- qPCR --- bisulphite --- gnathostomiasis --- schistosomiasis --- imported helminthiasis --- praziquantel --- parasitology --- zoonoses --- tropical medicine --- travel medicine --- global medicine --- Tasmania --- e-Diagnosis --- morphologist --- molecular parasitology --- social determinants of health --- cultural safety in health service delivery --- cultural competency --- Gnathostoma species --- larva migrans --- Okavango --- southern Africa --- tourists --- devil facial tumor disease --- parasite --- transmissible cancer --- MHC --- immune escape --- medical history --- military --- WW2 --- lymphatic filariasis --- Pacific --- n/a

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This Special Issue celebrates the 25th anniversary of the discovery of the first microRNA. The size of the microRNome and complexity of animal body plans and organ systems suggests a role for microRNAs in cell fate determination and differentiation. More than 2000 sequences have been proposed to represent unique microRNA genes in humans, with an increasing number of mechanistic roles identified in developmental, physiological, and pathological processes. Thus, dysregulation of a few key microRNAs can have a profound global effect on the gene expression and molecular programs of a cell. This great potential for clinical intervention has captured the interest and imagination of researchers in many fields. However, very few fields have been as prolific as the field of cancer research. This Special Issue provides but a glimpse of the large body of literature of microRNA biology in cancer research, containing 4 original research studies and 4 review articles that focus on specific hematologic or solid tumors in disease. Collectively, these articles highlight state-of-the-art approaches and methodologies for microRNA detection in tissue, blood, and other body fluids in a range of biomarkers applications, from early cancer detection to prognosis and treatment response. The articles also address some of the challenges regarding clinical implementation.

leukemia --- n/a --- cell lines --- hepatitis B virus --- long non coding RNA --- normalization of miRNA expression in RT-qPCR --- children --- colorectal --- review --- bevacizumab --- tumor budding cells --- oral cancer --- liquid biopsy --- hepatocellular carcinoma --- small t-antigen --- colorectal cancer --- protein-miRNA complex --- biomarkers --- biomarker --- interleukin-1? --- tissue analysis --- miRNAs --- T-cell acute lymphoblastic leukemia (T-ALL) --- leukoplakia --- inflammation --- exosomes --- circulating free DNA --- hepatitis C virus --- miRNA --- miR-21 --- extracellular microRNA --- endogenous controls --- lymphoma --- confocal slide scanning microscopy --- early diagnosis --- reference genes --- large T-antigen --- microRNA --- miRNA (microRNA) --- cancer --- TNF-? --- plasma --- MicroRNAs.