Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book collects 25 scientific articles from laboratories around the world, all of which use botulinum neurotoxins as the main protagonists of their studies. The use of botulinum neurotoxin in medicine, following its ability to inhibit the effects of various disorders of different etiology on the human organism, constitutes the main topic of each article presented here. This book, which is aimed at both students and medical professionals, attempts to summarize current knowledge about the use of botulinum toxin as a therapeutic agent in many diseases, ranging from spasticity to tremor, form motor dysfunction after stroke to neuropathic pain, from hyperactive muscle to migraine, and so on. Thanks to its simplified writing, accessible to an audience who may not be familiar with the mysteries of science, readers will get new insights into this biological toxin and its multiple applications, not simply relegated to its historical use to correct of face wrinkles. Both review and research articles are presented, not only concerning animal studies, but also clinical reports. This book will provide an up-to-date picture of the state-of-the-art of the possible development of novel applications of botulinum neurotoxins for future therapeutic purposes.

botulinum toxin --- limb tremors --- muscle selection --- biological effect --- various cell types --- neurotransmitter --- dermatology --- novel indication --- botulinum neurotoxin --- masticatory system --- maxillofacial bone --- dental occlusion --- orthognathic surgery --- sialorrhoea --- drooling --- salivary glands --- swallowing --- eccrine glands --- onabotulinumtoxin A --- incobotulinumtoxin A --- botulinum neurotoxins --- botulinum neurotoxin serotype A --- heavy chain --- botulinum neurotoxin serotype a heavy chain (BoNT/A HC) --- spinal cord injury (SCI) --- nerve regeneration --- growth associated protein 43 (GAP-43) --- superior cervical ganglion 10 (SCG10) --- neuronal processes --- neural regeneration --- Schwann cells --- glia --- spinal cord --- immunohistochemistry --- allodynia --- weight bearing --- sciatic static index --- walking track analysis --- itch --- SNARE --- VAMP --- mast cells --- compound 48/80 --- chloroquine --- spasticity --- botulinum toxin type A --- appropriate treatment --- Therapeutic Index --- pruritus --- antipruritic --- clinical --- experimental --- BoNT/A --- astroglia --- interleukins --- microglia --- TLR2 --- TLR4 --- Snap-23 --- pain --- cerebral palsy --- botulinum toxin A --- complex regional pain syndrome --- lumbar sympathetic ganglion block --- chronic pelvic pain --- overactive detrusor --- vaginism --- temporomandibular joint dislocation --- lateral pterygoid muscle --- botulinum toxin therapy --- synaptic transmission --- SNAP-25 --- epilepsy --- Parkinson’s disease --- neurotransmission blockade --- electrical activity --- prion disease --- new indications --- formulation --- delivery --- refractory chronic migraine --- tension headache --- medication overuse headache --- prophylactic treatment --- XEOMIN® --- BTX --- central neuropathic pain --- spinal cord injury --- post-stroke shoulder pain --- mouse test --- Clostridium tetani --- botulinum antitoxin --- food safety --- abobotulinumtoxinA --- upper limb spasticity --- post-stroke --- early use --- ONTIME --- clinical trial --- human --- urodynamics --- botulinum neurotoxin-A --- basal ganglia --- interspecies differences in motor behavior --- mouse --- rat --- interneurons --- hand tremor --- treatment --- electromyography --- kinematics --- essential tremor --- dystonic tremor --- tremor --- movement disorders --- Botulinum toxin --- upper limb biomechanics --- joint biomechanics --- diagnostic guidance --- clinical decision support --- spastic paresis --- electrical stimulation --- stroke management --- rehabilitation --- hand --- n/a --- Parkinson's disease

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The minimally invasive use of botulinum toxin (BoNT) in the lower urinary tract has revolutionized the treatment of debilitating bladder, urethra, and prostate conditions refractory to conventional therapy.  This is the first book focusing on the practical application of BoNT to the genitourinary tract.  An introductory section discusses the biology, pharmacology, and safety of BoNT in the lower urinary tract.  Applications of BoNT in the bladder and the prostate and pelvic floor are then covered in detail, with reviews of the latest clinical series and techniques of BoNT injection in both adults and children.  The book closes by considering non-genitourinary uses of BoNT and addressing issues of health economics as well as providing insights from experts from across the world.  This is a practical, hands-on book that also includes appendices containing easy to read instructions for patients undergoing bladder and prostate BoNT injections and specific nursing procedural issues.   The book is written in a concise, uniform, and clinically relevant style by two leading pioneers in the field, Drs. Michael Chancellor and Christopher Smith, who were the first to undertake comprehensive basic research into the mechanisms underlying the efficacy and potential uses of BoNT within the lower urinary tract.  Botulinum Toxin in Urology will be of interest to all urologists and urogynecologists who are considering the use of BoNT in their practice. .

Botulinum toxin -- Therapeutic use. --- Female Urogenital Diseases. --- Genitourinary organs -- Diseases -- Treatment. --- Pain -- Chemotherapy. --- Urology. --- Urology --- Metalloendopeptidases --- Female Urogenital Diseases --- Male Urogenital Diseases --- Bacterial Toxins --- Bacterial Proteins --- Diseases --- Metalloproteases --- Toxins, Biological --- Proteins --- Endopeptidases --- Female Urogenital Diseases and Pregnancy Complications --- Amino Acids, Peptides, and Proteins --- Biological Factors --- Peptide Hydrolases --- Hydrolases --- Chemicals and Drugs --- Enzymes --- Enzymes and Coenzymes --- Urologic Diseases --- Botulinum Toxins --- Medicine --- Health & Biological Sciences --- Urology & Nephrology --- Botulinum toxin. --- Botox (Trademark) --- Botulin --- Botulinismus toxin --- Botulinum neurotoxin --- Botulinus toxin --- Clostridium botulinum toxin --- Medicine. --- Gynecology. --- Neurology. --- Rehabilitation medicine. --- Medicine & Public Health. --- Rehabilitation Medicine. --- Genitourinary organs --- Bacterial toxins --- Neurotoxic agents --- Rehabilitation. --- Nervous system --- Neuropsychiatry --- Gynaecology --- Generative organs, Female --- Gynecology . --- Neurology . --- Medicine, Rehabilitation --- Rehabilitation medicine --- Rehabilitation --- Medicine, Physical --- Medical care. --- Health Care. --- Delivery of health care --- Delivery of medical care --- Health care --- Health care delivery --- Health services --- Healthcare --- Medical and health care industry --- Medical services --- Personal health services --- Public health