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546.92 --- Organoplatinum compounds --- Coordination compounds --- Chemistry, Physical and theoretical --- Complex compounds --- Sequestration (Chemistry) --- Platinum organic compounds --- Organotransition metal compounds --- Platinum compounds --- Platinum Pt --- 546.92 Platinum Pt --- Organoplatinum compounds. --- Organometallic compounds. --- Catalysis --- Platinum --- Reaction (chemistry)
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Antineoplastic agents --- Metals --- Pharmaceutical chemistry --- Platinum compounds --- Anti-Inflammatory Agents --- Antineoplastic Agents --- Chemistry, Pharmaceutical --- Gold --- Platinum --- Congresses --- Therapeutic use --- Congresses --- Congresses --- Therapeutic use --- Congresses --- congresses. --- congresses. --- Congresses. --- therapeutic use --- congresses. --- therapeutic use --- congresses.
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Chemistry of complexes --- fysicochemie --- Pharmacosynthesis. Pharmacochemistry --- Chelating Agents. --- 541.49:61 --- Coordination compounds --- Chemistry, Physical and theoretical --- Complex compounds --- Sequestration (Chemistry) --- Chelators --- Metal Chelating Agents --- Complexons --- Metal Antagonists --- Agents, Chelating --- Agents, Metal Chelating --- Antagonists, Metal --- Chelating Agents, Metal --- Antidotes --- Indicators and Reagents --- Coordination Complexes --- Complex compounds. Complex chemistry-:-Medical sciences --- Coordination compounds. --- Chelating agents --- Chelating agents. --- 541.49:61 Complex compounds. Complex chemistry-:-Medical sciences --- Chelating Agents --- Chelating Agent --- Chelator --- Agent, Chelating --- Luminescence. --- Organometallic compounds. --- Medicine. --- Medicine --- Neoplasm inhibitors --- Platinum compounds --- Ruthenium compounds
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In his thesis, Florian Schweinberger investigates the influence of the precise size of catalytically active species on reactivity. In order to do this he carries out studies both in UHV and under ambient conditions for supported, size-selected Platium clusters (8-68 atoms). Schweinberger probed the electronic structure, adsorption properties and reactivity of two olefins on surfaces and Pt clusters in the submonolayer range. With adsorbed trichloroethene (TCE) a possible cluster-adsorbate induced change in the electronic structure, and for ethene a low-temperature, size-dependent self-/hydrogenation was observed.In a collaborative approach, Schweinberger and colleagues investigated Pt clusters under ambient pressure conditions. They characterised the clusters at at the local and integral level and tested for temperature stability. Experiments in gas phase ?-reactors and in liquid, as part of a hybrid photocatalytic system, revealed size-dependent reactivity.Overall this thesis is not only of interest for those who want to perform similar experiments but also provides superb scientific insights for researchers in the field.
Catalysis. --- Platinum compounds. --- Chemistry. --- Renewable energy resources. --- Physical chemistry. --- Renewable energy sources. --- Alternate energy sources. --- Green energy industries. --- Physical Chemistry. --- Renewable and Green Energy. --- Activation (Chemistry) --- Chemistry, Physical and theoretical --- Surface chemistry --- Transition metal compounds --- Chemistry, Physical organic. --- Alternate energy sources --- Alternative energy sources --- Energy sources, Renewable --- Sustainable energy sources --- Power resources --- Renewable natural resources --- Agriculture and energy --- Chemistry, Physical organic --- Chemistry, Organic --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Chemistry
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Hamed Alborzinia uses the biosensor chip to monitor the metabolic and morphological changes in cancer cell lines in real time, particularly: (i) real-time measurements of basic cancer cell metabolism of different cancer cell lines; (ii) a detailed timeline of the metabolic response to cisplatin treatment and clear detection of the time span between start of cisplatin treatment and onset of cell death, which reflects the time required for the underlying molecular mechanisms of cell fate decision; (iii) direct functional measurement of the biological activity of a key regulatory protein of cellular metabolism following the kinetic change in respiration upon SIRT3 overexpression; and (iv) the time-resolved impact of several organometallic compounds on cell metabolism and cell morphology, including unexpected and not yet understood highly significant and specific effects on cell-cell interaction and adhesion. Contents Drug Screening with New Perspectives Real-Time Monitoring of Living Cells by a Novel Online Biosensor Chip Anticancer Agents – Effects Measured in Real Time Metabolism of Cancer Cells Target Groups Researchers and students in the fields of biotechnology and pharmacy The Author Hamed Alborzinia graduated in veterinary medicine from Shiraz University (Iran) in 2005 and continued in the Ph.D. program, now as post-Doc, with Prof. Dr. Stefan Wölfl at Heidelberg University (IPMB), using bioanalytical techniques in research on cancer cell metabolism.
Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Medicinal Chemistry. --- Medicine. --- Oncology. --- Toxicology. --- Biochemistry. --- Médecine --- Cancérologie --- Toxicologie --- Biochimie --- Medicine --- Health & Biological Sciences --- Oncology --- Drug monitoring. --- Cisplatin. --- Cancer cells --- Treatment. --- Cis-platinum --- Diamminedichloroplatinum --- Dichlorodiamine platinum --- Dichlorodiammineplatinum --- Platinum diamminedichloride --- Drugs --- Monitoring, Drug --- Therapeutic drug monitoring --- Monitoring --- Cancer research. --- Pharmacology. --- Medicinal chemistry. --- Alkylating agents --- Antineoplastic agents --- Chlorides --- Coordination compounds --- Metal-ammonia compounds --- Platinum compounds --- Patient monitoring --- Cells --- Pathology, Cellular --- Analysis --- Testing --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Tumors --- Composition --- Toxicology --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Drug effects --- Medical pharmacology --- Chemotherapy --- Pharmacy --- Cancer research --- Physiological effect
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