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Book
Crop Breeding : Methods and Protocols
Authors: ---
ISBN: 9781493904457 9781493904464 1493904450 1493904469 Year: 2014 Publisher: New York, NY : Springer New York : Imprint: Humana,

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Abstract

The recent advent of molecular technologies has changed the way plant breeders identify and select their germplasm as genetic variation can now be assessed at the DNA level. Crop Breeding: Methods and Protocols presents detailed guidelines and tutorials that suit different needs and capacity from small laboratories analyzing molecular markers on a one-by-one basis to the increasingly popular high-throughput protocols for high capacity laboratories. Topics covered include breeding strategy for the selection of an ideal variety or genetic ideotype, protocols for breeders using molecular markers in selection programs and for laboratories providing molecular services to breeding programs, statistical programs and software to aid implementation of molecular data into breeding programs, and methodologies that facilitate the generation of genetic diversity and its characterization. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.   Authoritative and easily accessible, Crop Breeding: Methods and Protocols will help in expanding the use of molecular technologies for the creation of tomorrow’s crop varieties.

Keywords

Plant breeding --- Breeding --- Genome, Plant --- Crops, Agricultural --- DNA Shuffling --- Genetic Markers --- Plants, Genetically Modified --- Methodology. --- methods --- genetics --- Genetic Processes --- Plants --- Biological Markers --- Genetic Engineering --- Plants, Edible --- Biology --- Publication Formats --- Phenotype --- Genome --- Reproductive Techniques --- Organisms, Genetically Modified --- Food --- Investigative Techniques --- Biological Factors --- Food and Beverages --- Eukaryota --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Genetic Phenomena --- Biological Science Disciplines --- Genetic Structures --- Genetic Techniques --- Organism Forms --- Publication Characteristics --- Organisms --- Phenomena and Processes --- Technology, Industry, Agriculture --- Chemicals and Drugs --- Natural Science Disciplines --- Disciplines and Occupations --- Genetics --- Laboratory Manuals --- Methods --- Agriculture --- Earth & Environmental Sciences --- Plant Sciences --- Methodology --- Genetic Marker --- Marker, Genetic --- Chromosome Markers --- DNA Markers --- Markers, DNA --- Markers, Genetic --- Chromosome Marker --- DNA Marker --- Marker, Chromosome --- Marker, DNA --- Markers, Chromosome --- Methodological Studies --- Methodological Study --- Procedures --- Studies, Methodological --- Study, Methodological --- Method --- Procedure --- Agricultural Crops --- Agricultural Crop --- In Vitro Exon Shuffling --- Exon Shuffling, In Vitro --- Molecular Breeding --- Breeding, Molecular --- Breedings, Molecular --- DNA Shufflings --- Molecular Breedings --- Shuffling, DNA --- Shufflings, DNA --- Plant Genome --- Genomes, Plant --- Plant Genomes --- GMO Plants --- Genetically Engineered Plants --- Genetically Modified Plants --- Plants, Transgenic --- Transgenic Plants --- Engineered Plant, Genetically --- Engineered Plants, Genetically --- GMO Plant --- Genetically Engineered Plant --- Genetically Modified Plant --- Modified Plant, Genetically --- Modified Plants, Genetically --- Plant, GMO --- Plant, Genetically Engineered --- Plant, Genetically Modified --- Plant, Transgenic --- Plants, GMO --- Plants, Genetically Engineered --- Transgenic Plant --- Breedings --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Genetic Technic --- Genetic Technics --- Genetic Technique --- Technic, Genetic --- Technics, Genetic --- Technique, Genetic --- Techniques, Genetic --- Genetic Structure --- Structure, Genetic --- Structures, Genetic --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Genetic Concepts --- Genetic Phenomenon --- Genetic Process --- Concept, Genetic --- Concepts, Genetic --- Genetic Concept --- Phenomena, Genetic --- Phenomenon, Genetic --- Process, Genetic --- Processes, Genetic --- Eucarya --- Eukarya --- Eukaryotes --- Eukaryotas --- Eukaryote --- Beverages and Food --- Biologic Agents --- Biologic Factors --- Biological Factor --- Factor, Biologic --- Factor, Biological --- Factors, Biological --- Biological Agents --- Agents, Biologic --- Agents, Biological --- Biologic Factor --- Factors, Biologic --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Nutrients --- Foods --- GMO Organisms --- Genetically Engineered Organisms --- Genetically Modified Organisms --- Organisms, Transgenic --- Transgenic Organisms --- Engineered Organism, Genetically --- Engineered Organisms, Genetically --- GMO Organism --- Genetically Engineered Organism --- Genetically Modified Organism --- Modified Organism, Genetically --- Modified Organisms, Genetically --- Organism, GMO --- Organism, Genetically Engineered --- Organism, Genetically Modified --- Organism, Transgenic --- Organisms, GMO --- Organisms, Genetically Engineered --- Transgenic Organism --- Reproduction Technics --- Reproduction Techniques --- Reproductive Technologies --- Technology, Reproductive --- Reproductive Technology --- Reproduction Technic --- Reproduction Technique --- Reproductive Technique --- Technic, Reproduction --- Technics, Reproduction --- Technique, Reproduction --- Technique, Reproductive --- Techniques, Reproduction --- Techniques, Reproductive --- Technologies, Reproductive --- Genomes --- Phenotypes --- Food Plants --- Edible Plant --- Edible Plants --- Food Plant --- Plant, Edible --- Plant, Food --- Plants, Food --- Engineering, Genetic --- Intervention, Genetic --- Genetic Intervention --- Genetic Interventions --- Interventions, Genetic --- Biochemical Marker --- Biologic Marker --- Biologic Markers --- Clinical Marker --- Immune Marker --- Immune Markers --- Immunologic Marker --- Laboratory Marker --- Marker, Biochemical --- Marker, Biological --- Marker, Clinical --- Marker, Immunologic --- Marker, Laboratory --- Marker, Serum --- Marker, Surrogate --- Serum Marker --- Surrogate End Point --- Surrogate End Points --- Surrogate Endpoint --- Surrogate Endpoints --- Surrogate Marker --- Viral Marker --- Biochemical Markers --- Clinical Markers --- Immunologic Markers --- Laboratory Markers --- Markers, Biochemical --- Markers, Biological --- Markers, Clinical --- Markers, Immunologic --- Markers, Laboratory --- Markers, Serum --- Markers, Surrogate --- Markers, Viral --- Serum Markers --- Surrogate Markers --- Viral Markers --- Biological Marker --- End Point, Surrogate --- End Points, Surrogate --- Endpoint, Surrogate --- Endpoints, Surrogate --- Marker, Biologic --- Marker, Immune --- Marker, Viral --- Markers, Biologic --- Markers, Immune --- Plant --- Crops --- Life sciences. --- Plant science. --- Botany. --- Plant genetics. --- Life Sciences. --- Plant Sciences. --- Plant Genetics & Genomics. --- Botanical science --- Phytobiology --- Phytography --- Phytology --- Plant biology --- Plant science --- Natural history --- Biosciences --- Science --- Plant Genetics and Genomics. --- Floristic botany


Book
Transgenic Wheat, Barley and Oats : Production and Characterization Protocols
Authors: ---
ISBN: 1588299619 159745379X Year: 2009 Publisher: Totowa, NJ : Humana Press : Imprint: Humana,

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Abstract

The understanding of the physical and genetic structure of plant genomes and the determination of phenotypes via interactions of coding and non-coding regions with the environment has quickly become the key to the future of plant breeding and agriculture. In Transgenic Wheat, Barley and Oats: Production and Characterization Protocols, expert investigators contribute the latest protocols for the transformation, regeneration and selection of these three species, using both biolistics and Agrobacterium tumefaciens, in order to fill the need for techniques and resources in this vital area of research. Covering such topics as in vitro Agrobacterium co-cultivation, the manipulation of gene expression, and GM risk assessment, this versatile collection focuses on the study of temperate small grain cereals while many of its readily reproducible procedures could be easily adapted to accommodate other cereals and plants. The in-depth chapters adhere to the highly successful Methods in Molecular Biology™ series format, featuring brief introductions to the subject, lists of the necessary materials and reagents, step-by-step laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Transgenic Wheat, Barley and Oats: Production and Characterization Protocols is an ideal guide for scientists pursuing this powerful, forward-thinking genetic strategy.

Keywords

Transgenic plants --- Wheat --- Barley --- Oats --- Avena sativa --- Hordeum --- Laboratory Manuals --- Triticum --- Plants, Genetically Modified --- Genetic Engineering --- Methods --- Genetics --- Cereals --- Animal Feed --- Publication Formats --- Biology --- Poaceae --- Investigative Techniques --- Organisms, Genetically Modified --- Plants --- Genetic Techniques --- Publication Characteristics --- Food --- Biological Science Disciplines --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Organism Forms --- Crops, Agricultural --- Angiosperms --- Eukaryota --- Embryophyta --- Food and Beverages --- Organisms --- Natural Science Disciplines --- Disciplines and Occupations --- Technology, Industry, Agriculture --- Streptophyta --- Viridiplantae --- Plant Sciences --- Agriculture --- Earth & Environmental Sciences --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Beverages and Food --- Land Plants --- Land Plant --- Plant, Land --- Plants, Land --- Eucarya --- Eukarya --- Eukaryotes --- Eukaryotas --- Eukaryote --- Angiospermae --- Liliopsida --- Magnoliopsida --- Angiosperm --- Liliopsidas --- Magnoliopsidas --- Agricultural Crops --- Agricultural Crop --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Nutrients --- Foods --- Genetic Technic --- Genetic Technics --- Genetic Technique --- Technic, Genetic --- Technics, Genetic --- Technique, Genetic --- Techniques, Genetic --- Plant --- GMO Organisms --- Genetically Engineered Organisms --- Genetically Modified Organisms --- Organisms, Transgenic --- Transgenic Organisms --- Engineered Organism, Genetically --- Engineered Organisms, Genetically --- GMO Organism --- Genetically Engineered Organism --- Genetically Modified Organism --- Modified Organism, Genetically --- Modified Organisms, Genetically --- Organism, GMO --- Organism, Genetically Engineered --- Organism, Genetically Modified --- Organism, Transgenic --- Organisms, GMO --- Organisms, Genetically Engineered --- Transgenic Organism --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Grass --- Imperata cylindrica --- Alopecurus --- Arundo --- Gramineae --- Grasses --- Imperata --- Fodder --- Animal Feeds --- Feed, Animal --- Feeds, Animal --- Fodders --- Cereal Grain --- Cereal --- Cereal Grains --- Edible Grains --- Grain, Cereal --- Grain, Edible --- Grains, Cereal --- Grains, Edible --- Methodological Studies --- Methodological Study --- Procedures --- Studies, Methodological --- Study, Methodological --- Method --- Procedure --- Engineering, Genetic --- Intervention, Genetic --- Genetic Intervention --- Genetic Interventions --- Interventions, Genetic --- GMO Plants --- Genetically Engineered Plants --- Genetically Modified Plants --- Plants, Transgenic --- Transgenic Plants --- Engineered Plant, Genetically --- Engineered Plants, Genetically --- GMO Plant --- Genetically Engineered Plant --- Genetically Modified Plant --- Modified Plant, Genetically --- Modified Plants, Genetically --- Plant, GMO --- Plant, Genetically Engineered --- Plant, Genetically Modified --- Plant, Transgenic --- Plants, GMO --- Plants, Genetically Engineered --- Transgenic Plant --- Durum Wheat --- Triticum aestivum --- Triticum durum --- Triticum spelta --- Triticum turgidum --- Triticum turgidum subsp. durum --- Triticum vulgare --- Durum Wheats --- Wheat, Durum --- Hordeum vulgare --- Avena --- Common oat --- Oat, Common --- GE crops (Genetically engineered crops) --- GE plants (Genetically engineered plants) --- Genetically engineered crops --- Genetically engineered plants --- Genetically modified crops --- Genetically modified plants --- GM crops (Genetically modified crops) --- GM plants (Genetically modified plants) --- Novel crops --- Transgenic crops --- methods --- Green Plants --- Green Plant --- Plant, Green --- Plants, Green --- Cultivated Oat --- Avenas --- Cultivated Oats --- Oat --- Oat, Cultivated --- Oats, Cultivated --- Chemistry. --- Biotechnology. --- Genetic engineering. --- Transgenic organisms. --- Genetic Engineering. --- Food Science. --- Transgenics. --- Food science. --- Science --- Genetically engineered organisms --- Genetically modified organisms --- GEOs (Genetically engineered organisms) --- GMOs (Genetically modified organisms) --- Genetic engineering --- Designed genetic change --- Gene splicing --- Genetic intervention --- Genetic surgery --- Genetic recombination --- Biotechnology --- Transgenic organisms --- Chemical engineering --- Food technology

Controversies in science and technology : from maize to menopause
Authors: --- ---
ISBN: 1282269623 9786612269622 029920393X 9780299203931 9780299203900 0299203905 9780299203948 0299203948 0299203905 0299203948 9781282269620 6612269626 Year: 2005 Publisher: Madison, Wis. : University of Wisconsin Press,

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Abstract

Written for general readers, teachers, journalists, and policymakers, this volume explores four controversial topics in science and technology, with commentaries from experts in such fields as sociology, religion, law, ethics, and politics: * Antibiotics and Resistance: the science, the policy debates, and perspectives from a microbiologist, a veterinarian, and an M.D. * Genetically Modified Maize and Gene Flow: the science of genetic modification, protecting genetic diversity, agricultural biotech vesus the environment, corporate patents versus farmers' rights * Hormone Replacement Theory and Menopause: overview of the Women's Health Initiative, history of hormone replacement therapy, the medicalization of menopause, hormone replacement therapy and clinical trials * Smallpox: historical and medical overview of smallpox, government policies for public health, the Emergency Health Powers Act, public resistance vs. cooperation.

Keywords

Biological Science Disciplines --- Terrorism --- Technology --- Biological Warfare --- Anti-Infective Agents --- Climacteric --- Hormone Replacement Therapy --- Technology, Industry, and Agriculture --- Organisms, Genetically Modified --- Plants --- Reproductive Physiological Phenomena --- Therapeutic Uses --- Eukaryota --- Sexual Development --- Organism Forms --- War --- Natural Science Disciplines --- Violence --- Drug Therapy --- Therapeutics --- Reproductive and Urinary Physiological Phenomena --- Social Problems --- Crime --- Reproductive Physiological Processes --- Pharmacologic Actions --- Chemical Actions and Uses --- Criminology --- Sociology --- Social Sciences --- Menopause --- Plants, Genetically Modified --- Estrogen Replacement Therapy --- Bioterrorism --- Biotechnology --- Anti-Bacterial Agents --- Agriculture --- Biology --- Health & Biological Sciences --- Genetics --- Agricultural Development --- Farming --- Development, Agricultural --- Agricultural Inoculants --- Anti-Bacterial Compounds --- Anti-Mycobacterial Agents --- Antibacterial Agents --- Antibiotic --- Antimycobacterial Agents --- Bacteriocidal Agents --- Bacteriocides --- Anti-Bacterial Agent --- Anti-Bacterial Compound --- Anti-Mycobacterial Agent --- Antibacterial Agent --- Antibiotics --- Antimycobacterial Agent --- Bacteriocidal Agent --- Bacteriocide --- Agent, Anti-Bacterial --- Agent, Anti-Mycobacterial --- Agent, Antibacterial --- Agent, Antimycobacterial --- Agent, Bacteriocidal --- Agents, Anti-Bacterial --- Agents, Anti-Mycobacterial --- Agents, Antibacterial --- Agents, Antimycobacterial --- Agents, Bacteriocidal --- Anti Bacterial Agent --- Anti Bacterial Agents --- Anti Bacterial Compound --- Anti Bacterial Compounds --- Anti Mycobacterial Agent --- Anti Mycobacterial Agents --- Compound, Anti-Bacterial --- Compounds, Anti-Bacterial --- Biotechnologies --- Biological Terrorism --- Terrorism, Biological --- Estrogen Progestin Combination Therapy --- Estrogen Progestin Replacement Therapy --- Estrogen Replacement --- Replacement, Estrogen --- Therapy, Estrogen Replacement --- Hormone Replacement Therapy, Post-Menopausal --- Postmenopausal Hormone Replacement Therapy --- Replacement Therapy, Estrogen --- Estrogen Replacement Therapies --- Estrogen Replacements --- Hormone Replacement Therapy, Post Menopausal --- Replacement Therapies, Estrogen --- Replacements, Estrogen --- Therapies, Estrogen Replacement --- GMO Plants --- Genetically Engineered Plants --- Genetically Modified Plants --- Plants, Transgenic --- Transgenic Plants --- Engineered Plant, Genetically --- Engineered Plants, Genetically --- GMO Plant --- Genetically Engineered Plant --- Genetically Modified Plant --- Modified Plant, Genetically --- Modified Plants, Genetically --- Plant, GMO --- Plant, Genetically Engineered --- Plant, Genetically Modified --- Plant, Transgenic --- Plants, GMO --- Plants, Genetically Engineered --- Transgenic Plant --- Genetic Engineering --- Transgenes --- Food, Genetically Modified --- Plantibodies --- Salt-Tolerant Plants --- Molecular Farming --- Change of Life, Female --- Science, Social --- Sciences, Social --- Social Science --- General Social Development and Population --- Chemical Actions --- Actions, Chemical --- Actions, Pharmacologic --- Pharmacological and Toxicological Phenomena --- Reproductive Physiologic Concepts --- Reproductive Physiological Phenomenon --- Reproductive Physiological Process --- Reproductive Physiological Concepts --- Concept, Reproductive Physiologic --- Concept, Reproductive Physiological --- Concepts, Reproductive Physiologic --- Concepts, Reproductive Physiological --- Phenomena, Reproductive Physiological --- Phenomenon, Reproductive Physiological --- Physiologic Concept, Reproductive --- Physiologic Concepts, Reproductive --- Physiological Concept, Reproductive --- Physiological Process, Reproductive --- Physiological Processes, Reproductive --- Process, Reproductive Physiological --- Processes, Reproductive Physiological --- Reproductive Physiologic Concept --- Reproductive Physiological Concept --- Kidnapping --- Poaching --- Crimes --- Kidnappings --- Criminal Behavior --- Labor Exploitation --- Social Exploitation --- Exploitation, Labor --- Exploitation, Social --- Exploitations, Labor --- Problem, Social --- Problems, Social --- Social Problem --- Physiology, Reproductive and Urinary --- Reproductive and Urinary Physiological Phenomenon --- Reproductive and Urinary Physiology Concepts --- Reproductive and Urinary Physiology Phenomenon --- Reproductive and Urinary Tract Physiological Concepts --- Reproductive and Urinary Tract Physiological Phenomena --- Reproductive and Urinary Tract Physiological Phenomenon --- Reproductive and Urinary Tract Physiology --- Reproductive and Urinary Physiology --- Reproductive and Urinary Physiology Phenomena --- Therapy --- Treatment --- Therapeutic --- Therapies --- Treatments --- Disease --- Therapy, Drug --- Chemotherapy --- Pharmacotherapy --- Chemotherapies --- Drug Therapies --- Pharmacotherapies --- Therapies, Drug --- Pharmaceutical Preparations --- Assaultive Behavior --- Atrocities --- Behavior, Assaultive --- Structural Violence --- Violence, Structural --- Riots --- Warfare --- Crime Victims --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Wars --- Armed Conflict --- Conflict, Armed --- Conflicts, Armed --- GMO Organism --- GMO Organisms --- Genetically Engineered Organisms --- Genetically Modified Organism --- Modified Organism, Genetically --- Organism, Genetically Modified --- Organism, Transgenic --- Organisms, Genetically Engineered --- Genetically Modified Organisms --- Organisms, Transgenic --- Transgenic Organisms --- Sex Development --- Development, Sex --- Development, Sexual --- Eucarya --- Eukarya --- Eukaryotes --- Eukaryotas --- Eukaryote --- Therapeutic Effects --- Therapeutic Effect --- Therapeutic Use --- Effect, Therapeutic --- Effects, Therapeutic --- Use, Therapeutic --- Uses, Therapeutic --- Plant --- Botany --- Plant Proteins --- Ethnopharmacology --- Therapy, Hormone Replacement --- Replacement Therapy, Hormone --- Hormone Replacement Therapies --- Replacement Therapies, Hormone --- Therapies, Hormone Replacement --- Change of Life --- Climacterics --- Life Change --- Life Changes --- Anti-Microbial Agents --- Antiinfective Agents --- Antimicrobial Agents --- Anti-Infective Agent --- Anti-Microbial Agent --- Antimicrobial Agent --- Microbicide --- Microbicides --- Agent, Anti-Infective --- Agent, Anti-Microbial --- Agent, Antimicrobial --- Agents, Anti-Infective --- Agents, Anti-Microbial --- Agents, Antiinfective --- Agents, Antimicrobial --- Anti Infective Agent --- Anti Infective Agents --- Anti Microbial Agent --- Anti Microbial Agents --- Infections --- Parasites --- Biologic Warfare --- Warfare, Bacterial --- Warfare, Biological --- Bacterial Warfare --- Warfare, Biologic --- Arts, Industrial --- Industrial Arts --- Cloud Computing --- Radioactive Terrorism --- Terrorism, Radioactive --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- therapy --- drug therapy --- therapeutic use --- Biotechnology. --- Anti-Bacterial Agents. --- Bioterrorism. --- Estrogen Replacement Therapy. --- Menopause. --- Plants, Genetically Modified. --- Antibiotics in agriculture --- Genetic engineering --- Science --- Hormone therapy --- Social aspects. --- Biocrime --- Biocrimes --- Agronomy --- Agronomies --- Science and society --- Sociology of science --- Bio-terrorism --- Biological terrorism --- Change of life in women --- Female change of life --- Female climacteric --- Law and legislation

Xenotransplantation : International Policy Issues
Author:
ISBN: 1280034084 9786610034086 9264172653 9264170308 Year: 1999 Publisher: Paris : OECD Publishing,

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Abstract

Over one million people world-wide have benefited from successful tissue and organ transplants and survival rates have dramatically improved. But transplantation has become a victim of its own success. The demand for human organs can no longer be met and deaths of persons on waiting lists have more than doubled since 1988. A number of alternatives have been proposed to fill the gap between the supply and demand of organs and the past few years have seen the development of various approaches derived from recent advances in biotechnology. Among these technologies is xenotransplantation - the transplantation of viable cells, tissues and organs from one animal species to another. Xenotransplantation of cells and tissues has been approved for clinical trials in a number of OECD countries. However, opinions about the risks from these early procedures and whether to proceed any further vary. At the New York 1998 Workshop on "International issues in transplantation biotechnology including the use of non-human cells, tissues and organs", world leaders in the field reported on the state of the art and unmet needs in transplantation, addressing in particular the potential, the risks, the ethics and socio-economic impacts of xenotransplantation. Based on presentations, transcripts of round-table discussions and comments raised at the workshop, this book provides an overview of the field and of current regulatory frameworks and addresses the most pressing international policy considerations on xenotransplantation.

Keywords

Science and Technology --- Xenografts --- Transplantation of organs, tissues, etc --- Transplantation immunology --- Artiodactyla --- Health Care Evaluation Mechanisms --- Social Control Policies --- Technology, Industry, and Agriculture --- Infection --- Transplantation --- Investigative Techniques --- Probability --- Epidemiologic Methods --- Mammals --- Outcome Assessment (Health Care) --- Social Sciences --- Mathematics --- Animal Population Groups --- Health Care Economics and Organizations --- Environment and Public Health --- Eukaryota --- Sociology --- Health Services --- Health --- Culture --- Research --- Medicine --- Art --- Persons --- Prognosis --- Biomedical Research --- Organisms, Genetically Modified --- Natural Science Disciplines --- Technology, Industry, Agriculture --- Organism Forms --- Named Groups --- Health Occupations --- Science --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Quality of Health Care --- Diagnosis --- Policy --- Health Care --- Anthropology, Education, Sociology and Social Phenomena --- Mathematical Concepts --- Health Care Facilities, Manpower, and Services --- Population Characteristics --- Humanities --- Outcome and Process Assessment (Health Care) --- Organisms --- Vertebrates --- Surgical Procedures, Operative --- Anthropology, Cultural --- Bacterial Infections and Mycoses --- Phenomena and Processes --- Disciplines and Occupations --- Anthropology --- Health Care Quality, Access, and Evaluation --- Diseases --- Chordata --- Health Services Administration --- Animal Welfare --- Animals, Genetically Modified --- Primates --- Swine --- Public Policy --- Economics --- Human Body --- Public Health --- Risk --- Statistics as Topic --- Animal Experimentation --- Developing Countries --- Transplantation, Heterologous --- Human Experimentation --- International Cooperation --- Animals --- Social Control, Formal --- Tissue Donors --- Treatment Outcome --- Internationality --- Tissue and Organ Procurement --- Industry --- Organ Transplantation --- Communicable Diseases --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Government policy --- Animal Cruelty --- Cruelty, Animal --- Welfare, Animal --- Administration, Health Services --- Chordates --- Chordate --- Healthcare Quality, Access, and Evaluation --- Cultural Anthropology --- Ethnography --- Ethnographies --- Ghost Surgery --- Operative Procedures --- Operative Surgical Procedure --- Operative Surgical Procedures --- Procedure, Operative Surgical --- Procedures, Operative Surgical --- Surgery, Ghost --- Surgical Procedure, Operative --- Operative Procedure --- Procedure, Operative --- Procedures, Operative --- Vertebrate --- Donabedian Model --- Donabedian Triad --- Outcome and Process Assessment --- Structure Process Outcome Triad --- Model, Donabedian --- Triad, Donabedian --- Population Heterogeneity --- Population Statistics --- Characteristic, Population --- Characteristics, Population --- Heterogeneity, Population --- Population Characteristic --- Statistics, Population --- Healthcare Facilities, Manpower, and Services --- Concept, Mathematical --- Concepts, Mathematical --- Mathematical Concept --- Community-Based Distribution --- Contraceptive Distribution --- Delivery of Healthcare --- Dental Care Delivery --- Distribution, Non-Clinical --- Distribution, Nonclinical --- Distributional Activities --- Healthcare --- Healthcare Delivery --- Healthcare Systems --- Non-Clinical Distribution --- Nonclinical Distribution --- Delivery of Dental Care --- Health Care Delivery --- Health Care Systems --- Activities, Distributional --- Activity, Distributional --- Care, Health --- Community Based Distribution --- Community-Based Distributions --- Contraceptive Distributions --- Deliveries, Healthcare --- Delivery, Dental Care --- Delivery, Health Care --- Delivery, Healthcare --- Distribution, Community-Based --- Distribution, Contraceptive --- Distribution, Non Clinical --- Distributional Activity --- Distributions, Community-Based --- Distributions, Contraceptive --- Distributions, Non-Clinical --- Distributions, Nonclinical --- Health Care System --- Healthcare Deliveries --- Healthcare System --- Non Clinical Distribution --- Non-Clinical Distributions --- Nonclinical Distributions --- System, Health Care --- System, Healthcare --- Systems, Health Care --- Systems, Healthcare --- Policies --- Antemortem Diagnosis --- Diagnoses and Examinations --- Examinations and Diagnoses --- Postmortem Diagnosis --- Antemortem Diagnoses --- Diagnoses --- Diagnoses, Antemortem --- Diagnoses, Postmortem --- Diagnosis, Antemortem --- Diagnosis, Postmortem --- Postmortem Diagnoses --- Disease --- Quality of Care --- Quality of Healthcare --- Care Qualities --- Care Quality --- Health Care Quality --- Healthcare Quality --- Sciences --- Health Professions --- Health Occupation --- Health Profession --- Occupation, Health --- Occupations, Health --- Profession, Health --- Professions, Health --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- GMO Organisms --- Genetically Engineered Organisms --- Genetically Modified Organisms --- Organisms, Transgenic --- Transgenic Organisms --- Engineered Organism, Genetically --- Engineered Organisms, Genetically --- GMO Organism --- Genetically Engineered Organism --- Genetically Modified Organism --- Modified Organism, Genetically --- Modified Organisms, Genetically --- Organism, GMO --- Organism, Genetically Engineered --- Organism, Genetically Modified --- Organism, Transgenic --- Organisms, GMO --- Organisms, Genetically Engineered --- Transgenic Organism --- Experimental Medicine --- Investigational Medicine --- Investigative Medicine --- Research, Biomedical --- Research, Medical --- Medical Research --- Medicine, Experimental --- Medicine, Investigational --- Medicine, Investigative --- Prognostic Factors --- Factor, Prognostic --- Factors, Prognostic --- Prognoses --- Prognostic Factor --- Person --- Arts --- Medical Specialities --- Medical Specialties --- Medical Specialty --- Specialities, Medical --- Specialties, Medical --- Specialty, Medical --- Medical Speciality --- Speciality, Medical --- Laboratory Research --- Research Activities --- Research and Development --- Research Priorities --- Activities, Research --- Activity, Research --- Development and Research --- Priorities, Research --- Priority, Research --- Research Activity --- Research Priority --- Research, Laboratory --- Beliefs --- Cultural Background --- Customs --- Background, Cultural --- Backgrounds, Cultural --- Belief --- Cultural Backgrounds --- Cultures --- Custom --- Normalcy --- Normality --- Normalities --- Services, Health --- Health Service --- Service, Health --- General Social Development and Population --- Eucarya --- Eukarya --- Eukaryotes --- Eukaryotas --- Eukaryote --- Healthcare Economics and Organizations --- Animal Population Group --- Population Group, Animal --- Population Groups, Animal --- Mathematic --- Science, Social --- Sciences, Social --- Social Science --- Assessment, Outcomes --- Outcome Measures --- Outcome Studies --- Outcomes Assessment --- Outcomes Research --- Assessment, Outcome (Health Care) --- Assessments, Outcome (Health Care) --- Assessments, Outcomes --- Measure, Outcome --- Measures, Outcome --- Outcome Assessments (Health Care) --- Outcome Measure --- Outcome Study --- Outcomes Assessments --- Research, Outcomes --- Studies, Outcome --- Study, Outcome --- Mammalia --- Mammal --- Epidemiologic Method --- Epidemiological Methods --- Methods, Epidemiologic --- Epidemiological Method --- Method, Epidemiologic --- Method, Epidemiological --- Methods, Epidemiological --- Epidemiology --- Probabilities --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Transplantations --- Infections --- Control Policies, Social --- Control Policy, Social --- Policies, Social Control --- Policy, Social Control --- Social Control Policy --- Healthcare Evaluation Mechanisms --- Evaluation Mechanism, Healthcare --- Evaluation Mechanisms, Healthcare --- Healthcare Evaluation Mechanism --- Mechanism, Healthcare Evaluation --- Mechanisms, Healthcare Evaluation --- Hippopotamus --- Peccary --- Artiodactylas --- Peccaries --- Medical transplantation --- Organ transplantation --- Organ transplants --- Organs (Anatomy) --- Surgical transplantation --- Tissue transplantation --- Tissues --- Transplants, Organ --- Heterografts --- Heterologous transplants --- Heteroplastic grafts --- Xenotransplantation --- Infectious Diseases --- Communicable Disease --- Disease, Communicable --- Disease, Infectious --- Diseases, Communicable --- Diseases, Infectious --- Infectious Disease --- Grafting, Organ --- Transplantation, Organ --- Graftings, Organ --- Organ Grafting --- Organ Graftings --- Organ Transplantations --- Transplantations, Organ --- Tertiary Sector --- Industries --- Sector, Tertiary --- Sectors, Tertiary --- Tertiary Sectors --- Donor Cards --- Organ Donation --- Required Organ Donation Request --- Required Request --- Tissue Donation --- Organ Procurement --- Organ Procurement Systems --- Tissue Procurement --- Card, Donor --- Cards, Donor --- Donor Card --- Organ Donations --- Organ Procurement System --- Organ Procurements --- Required Requests --- Tissue Donations --- Tissue Procurements --- Globalization --- International Aspects --- International Perspectives --- International Relations --- Multinational Aspects --- Multinational Perspectives --- Aspect, International --- Aspect, Multinational --- Aspects, International --- Aspects, Multinational --- International Aspect --- International Perspective --- Multinational Aspect --- Multinational Perspective --- Perspective, International --- Perspective, Multinational --- Perspectives, International --- Perspectives, Multinational --- Relations, International --- Clinical Effectiveness --- Clinical Efficacy --- Patient-Relevant Outcome --- Treatment Efficacy --- Rehabilitation Outcome --- Treatment Effectiveness --- Clinical Effectivenesses --- Effectiveness, Clinical --- Effectiveness, Treatment --- Effectivenesses, Clinical --- Efficacy, Clinical --- Efficacy, Treatment --- Outcome, Patient-Relevant --- Outcome, Rehabilitation --- Outcome, Treatment --- Outcomes, Patient-Relevant --- Patient Relevant Outcome --- Patient-Relevant Outcomes --- Donors --- Ovum Donors --- Semen Donors --- Transplant Donors --- Organ Donors --- Donor --- Donor, Organ --- Donor, Ovum --- Donor, Semen --- Donor, Tissue --- Donor, Transplant --- Donors, Organ --- Donors, Ovum --- Donors, Semen --- Donors, Tissue --- Donors, Transplant --- Organ Donor --- Ovum Donor --- Semen Donor --- Tissue Donor --- Transplant Donor --- Regulation --- Social Control --- Control, Social --- Controls, Social --- Formal Social Control --- Formal Social Controls --- Regulations --- Social Controls --- Animalia --- Animal --- Metazoa --- Treaties --- Foreign Aid --- Aid, Foreign --- Cooperation, International --- Treaty --- Human Research Subject Protection --- Experimentation, Human --- Heterograft Transplantation --- Heterografting --- Heterologous Transplantation --- Xenograft Transplantation --- Xenografting --- Transplantation, Heterograft --- Transplantation, Xenograft --- Developing Nations --- Least Developed Countries --- Less-Developed Nations --- Third-World Nations --- Under-Developed Nations --- Less-Developed Countries --- Third-World Countries --- Under-Developed Countries --- Countries, Developing --- Countries, Least Developed --- Countries, Less-Developed --- Countries, Third-World --- Countries, Under-Developed --- Country, Developing --- Country, Least Developed --- Country, Less-Developed --- Country, Third-World --- Country, Under-Developed --- Developed Countries, Least --- Developed Country, Least --- Developing Country --- Developing Nation --- Least Developed Country --- Less Developed Countries --- Less Developed Nations --- Less-Developed Country --- Less-Developed Nation --- Nation, Less-Developed --- Nation, Third-World --- Nation, Under-Developed --- Nations, Developing --- Nations, Less-Developed --- Nations, Third-World --- Nations, Under-Developed --- Third World Countries --- Third World Nations --- Third-World Country --- Third-World Nation --- Under Developed Countries --- Under Developed Nations --- Under-Developed Country --- Under-Developed Nation --- Animal Experimental Use --- Animal Experiments --- Animal Research --- Animal Experiment --- Animal Experimental Uses --- Experiment, Animal --- Experimental Use, Animal --- Experimental Uses, Animal --- Experimentation, Animal --- Experiments, Animal --- Research, Animal --- Area Analysis --- Correlation Studies --- Correlation Study --- Correlation of Data --- Data Analysis --- Estimation Technics --- Estimation Techniques --- Indirect Estimation Technics --- Indirect Estimation Techniques --- Multiple Classification Analysis --- Service Statistics --- Statistical Study --- Statistics, Service --- Tables and Charts as Topic --- Analyses, Area --- Analyses, Data --- Analyses, Multiple Classification --- Analysis, Area --- Analysis, Data --- Analysis, Multiple Classification --- Area Analyses --- Classification Analyses, Multiple --- Classification Analysis, Multiple --- Data Analyses --- Data Correlation --- Data Correlations --- Estimation Technic --- Estimation Technic, Indirect --- Estimation Technics, Indirect --- Estimation Technique --- Estimation Technique, Indirect --- Estimation Techniques, Indirect --- Indirect Estimation Technic --- Indirect Estimation Technique --- Multiple Classification Analyses --- Statistical Studies --- Studies, Correlation --- Studies, Statistical --- Study, Correlation --- Study, Statistical --- Technic, Estimation --- Technic, Indirect Estimation --- Technics, Estimation --- Technics, Indirect Estimation --- Technique, Estimation --- Technique, Indirect Estimation --- Techniques, Estimation --- Techniques, Indirect Estimation --- Relative Risk --- Relative Risks --- Risk, Relative --- Risks --- Risks, Relative --- Environment, Preventive Medicine & Public Health --- Environment, Preventive Medicine and Public Health --- Health, Public --- Body Parts --- Body Parts and Fluids --- Body, Human --- Human Figure --- Bodies, Human --- Figure, Human --- Figures, Human --- Human Bodies --- Human Figures --- Parts, Body --- Capital --- Conditions, Economic --- Consumption --- Cost of Living --- Easterlin Hypothesis --- Economic Conditions --- Economic Factors --- Economic Policies --- Economic Policy --- Economics, Home --- Factors, Economic --- Home Economics --- Household Consumption --- Macroeconomic Factors --- Microeconomic Factors --- Policies, Economic --- Policy, Economic --- Production --- Remittances --- Utility Theory --- Consumer Price Index --- Condition, Economic --- Consumer Price Indices --- Consumption, Household --- Economic Condition --- Economic Factor --- Factor, Economic --- Factor, Macroeconomic --- Factor, Microeconomic --- Factors, Macroeconomic --- Factors, Microeconomic --- Household Consumptions --- Hypothesis, Easterlin --- Index, Consumer Price --- Indices, Consumer Price --- Living Cost --- Living Costs --- Remittance --- Theories, Utility --- Theory, Utility --- Utility Theories --- Migration Policy --- Population Policy --- Social Protection --- Social Policy --- Migration Policies --- Policies, Migration --- Policies, Population --- Policies, Public --- Policies, Social --- Policy, Migration --- Policy, Population --- Policy, Public --- Policy, Social --- Population Policies --- Protection, Social --- Public Policies --- Social Policies --- Wart Hogs --- Phacochoerus --- Pigs --- Suidae --- Warthogs --- Hog, Wart --- Hogs, Wart --- Wart Hog --- Primate --- Founder Animals, Transgenic --- GMO Animals --- Genetically Engineered Animals --- Animals, Transgenic --- Genetically Modified Animals --- Transgenic Animals --- Animal, GMO --- Animal, Genetically Engineered --- Animal, Genetically Modified --- Animal, Transgenic --- Animal, Transgenic Founder --- Animals, GMO --- Animals, Genetically Engineered --- Animals, Transgenic Founder --- Engineered Animal, Genetically --- Engineered Animals, Genetically --- Founder Animal, Transgenic --- GMO Animal --- Genetically Engineered Animal --- Genetically Modified Animal --- Modified Animal, Genetically --- Modified Animals, Genetically --- Transgenic Animal --- Transgenic Founder Animal --- Transgenic Founder Animals --- organization & administration --- diagnosis --- methods --- Vivisection --- Animal Use Alternatives --- Euthanasia, Animal --- Qualitative Research --- General Surgery --- Pharmacy Audit --- Audit, Pharmacy --- Pharmacy Audits --- Occupations --- Genetic Engineering --- Transgenes --- Food, Genetically Modified --- Animals, Laboratory --- Ethics, Research --- Zoology --- Transplantation Immunology --- Transplantation Conditioning --- Surgery --- Preservation of organs, tissues, etc. --- Procurement of organs, tissues, etc. --- Transplantation of organs, tissues, etc. --- Disease Outbreaks --- Disease Transmission, Infectious --- Commerce --- Ethics, Business --- Tissue and Organ Harvesting --- International Law --- Lysholm Knee Score --- Tissue Transplantation --- Directed Tissue Donation --- Transplant Donor Site --- Helsinki Declaration --- Bioethical Issues --- Embryo Research --- Fetal Research --- Research Subjects --- Models, Animal --- Risk Reduction Behavior --- Harm Reduction --- Community Health --- Health, Community --- Preventive Medicine --- Education, Public Health Professional --- Policy Making --- Molecular Farming --- Health Workforce --- Material Culture --- Culture, Material --- Material Cultures --- Cultural Relativism --- Cultural Relativisms --- Relativism, Cultural --- Relativisms, Cultural --- Infection and Infestation --- Infections and Infestations --- Infestation and Infection --- Infestations and Infections --- Affirmative Action --- Action, Affirmative --- Surgical Procedures --- Procedure, Surgical --- Procedures, Surgical --- Surgical Procedure --- Diagnose --- Health Care Economics --- Health Economics --- Healthcare Economics --- Care Economic, Health --- Economic, Health --- Economic, Health Care --- Economic, Healthcare --- Economics, Health Care --- Health Care Economic --- Health Economic --- Healthcare Economic --- Transplant surgery --- Transplantation surgery --- Incidence --- Transplantation, Heterologous. --- Public Policy. --- Hétérogreffes --- Greffe (Chirurgie) --- Congresses --- Congresses. --- Politique gouvernementale --- Congrès --- Immunologie

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