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From patient referral to post-therapy management, Chimeric Antigen Receptor (CAR) T-Cell Therapies for Cancer: A Practical Guide presents a comprehensive view of CAR modified T-cells in a concise and practical format. Providing authoritative guidance on the implementation and management of CAR T-cell therapy from Drs. Daniel W. Lee and Nirali N. Shah, this clinical resource keeps you up to date on the latest developments in this rapidly evolving area. Covers all clinical aspects, including patient referral, toxicities management, comorbidities, bridging therapy, post-CAR monitoring, and multidisciplinary approaches to supportive care. Includes key topics on associated toxicities such as predictive biomarkers, infections, and multidisciplinary approaches to supportive care. Presents current knowledge on FDA approved CAR T-cell products as well as developments on the horizon. Editors and authors represent leading investigators in academia and worldwide pioneers of CAR therapy.

Oncology. Neoplasms --- T cells --- Tumor antigens. --- Receptors, Chimeric Antigen --- Neoplasms --- Immunotherapy, Adoptive. --- Receptors, Antigen, T-Cell. --- Cell- and Tissue-Based Therapy. --- Receptors. --- therapeutic use. --- therapy.

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Modern cell biology has brought improvements in therapy for advanced malignant diseases through immunomodulation, hematopoietic stem cell transplantation, and other advanced techniques. Collected here are selected papers from the Fifth International Symposium of Keio University for Life Sciences and Medicine on Cell Therapy. All chapters include innovative basic research for clinical application: immunotherapy, cancer vaccination, molecular biology of hematopoietic stem cells, stem cell processing, and gene therapy. The book is divided into three parts: Immunotherapy for malignant diseases; Hematopoietic stem cell biology and clinical application; and International collaboration in hematopoietic stem cell transplantation. Included in the third part is information on bone marrow registries from around the world. The book thus presents up-to-date information on biological and clinical aspects of treatment, with insight into the future of cell therapy.

Hematopoietic Stem Cell Transplantation. --- Hematopoietic Stem Cells --- Immunotherapy, Adoptive. --- Neoplasms --- Cellular therapy --- Cell therapy --- Cells --- Therapy, Cellular --- Organotherapy --- Therapeutics, Physiological --- Transplantation of organs, tissues, etc. --- Cell transplantation --- Adoptive Immunotherapy --- Cellular Immunotherapy, Adoptive --- Immunotherapy, Adoptive Cellular --- Adoptive Cellular Immunotherapy --- Adoptive Cellular Immunotherapies --- Adoptive Immunotherapies --- Cellular Immunotherapies, Adoptive --- Immunotherapies, Adoptive --- Immunotherapies, Adoptive Cellular --- Killer Cells, Lymphokine-Activated --- Cytapheresis --- Lymphocytes, Tumor-Infiltrating --- Monocytes, Activated Killer --- Transplantation, Hematopoietic Stem Cell --- Stem Cell Transplantation, Hematopoietic --- Bone Marrow Transplantation --- Bone Marrow Purging --- Hematopoietic Stem Cell Mobilization --- physiology. --- therapy. --- Therapeutic use --- transplantation --- Hematopoietic Stem Cell Transplantation --- Immunotherapy, Adoptive --- physiology --- therapy --- Physiology --- Therapy --- CAR T-Cell Therapy --- Chimeric Antigen Receptor Therapy --- CAR T Cell Therapy --- CAR T-Cell Therapies --- T-Cell Therapies, CAR --- T-Cell Therapy, CAR --- Therapies, CAR T-Cell --- Therapy, CAR T-Cell --- Receptors, Chimeric Antigen --- Cell biology. --- Molecular biology. --- Oncology  . --- Cell Biology. --- Molecular Medicine. --- Oncology. --- Tumors --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Cell biology --- Cellular biology --- Biology

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Hematopoietic stem cells --- Cellular therapy --- Hematopoietic stem cell disorders --- Cellular therapy. --- Hematopoietic Stem Cell Transplantation. --- Immunotherapy, Adoptive. --- Transplantation --- Treatment. --- Transplantation. --- Adoptive Immunotherapy --- CAR T-Cell Therapy --- Cellular Immunotherapy, Adoptive --- Chimeric Antigen Receptor Therapy --- Immunotherapy, Adoptive Cellular --- Adoptive Cellular Immunotherapy --- Adoptive Cellular Immunotherapies --- Adoptive Immunotherapies --- CAR T Cell Therapy --- CAR T-Cell Therapies --- Cellular Immunotherapies, Adoptive --- Immunotherapies, Adoptive --- Immunotherapies, Adoptive Cellular --- T-Cell Therapies, CAR --- T-Cell Therapy, CAR --- Therapies, CAR T-Cell --- Therapy, CAR T-Cell --- Receptors, Chimeric Antigen --- Killer Cells, Lymphokine-Activated --- Cytapheresis --- Lymphocytes, Tumor-Infiltrating --- Monocytes, Activated Killer --- Transplantation, Hematopoietic Stem Cell --- Stem Cell Transplantation, Hematopoietic --- Hematopoietic Stem Cells --- Bone Marrow Transplantation --- Bone Marrow Purging --- Hematopoietic Stem Cell Mobilization --- HSCs (Hematopoietic stem cells) --- Blood cells --- Bone marrow cells --- Hematopoietic system --- Multipotent stem cells --- Cell therapy --- Cells --- Therapy, Cellular --- Organotherapy --- Therapeutics, Physiological --- Transplantation of organs, tissues, etc. --- Cell transplantation --- Hematopoietic stem cell diseases --- Blood --- transplantation --- Therapeutic use --- Diseases

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T cells --- Tumor antigens. --- Receptors, Chimeric Antigen --- Neoplasms --- Immunotherapy, Adoptive. --- Receptors, Antigen, T-Cell. --- Cell- and Tissue-Based Therapy. --- Receptors. --- therapeutic use. --- therapy. --- Therapy, Cell --- Therapy, Tissue --- Cell Therapy --- Tissue Therapy --- Cell and Tissue Based Therapy --- Tissue Therapy, Historical --- Receptors, T-Cell Antigen --- T-Cell Antigen Receptor --- T-Cell Receptor --- Antigen Receptors, T-Cell --- T-Cell Receptors --- Antigen Receptor, T-Cell --- Antigen Receptors, T Cell --- Receptor, T-Cell --- Receptor, T-Cell Antigen --- Receptors, T Cell Antigen --- Receptors, T-Cell --- T Cell Antigen Receptor --- T Cell Receptor --- T Cell Receptors --- T-Cell Antigen Receptors --- CD3 Complex --- Genes, T-Cell Receptor --- Complementarity Determining Regions --- Adoptive Immunotherapy --- CAR T-Cell Therapy --- Cellular Immunotherapy, Adoptive --- Chimeric Antigen Receptor Therapy --- Immunotherapy, Adoptive Cellular --- Adoptive Cellular Immunotherapy --- Adoptive Cellular Immunotherapies --- Adoptive Immunotherapies --- CAR T Cell Therapy --- CAR T-Cell Therapies --- Cellular Immunotherapies, Adoptive --- Immunotherapies, Adoptive --- Immunotherapies, Adoptive Cellular --- T-Cell Therapies, CAR --- T-Cell Therapy, CAR --- Therapies, CAR T-Cell --- Therapy, CAR T-Cell --- Killer Cells, Lymphokine-Activated --- Cytapheresis --- Lymphocytes, Tumor-Infiltrating --- Monocytes, Activated Killer --- Antigens --- Tumor markers --- T cell receptors --- T lymphocyte antigen receptors --- Cell receptors

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This book gives an updated review of the state of the art in regenerative cell therapy in the fields of cardiology, hematology, pediatrics, neurology, orthopedics and infectious diseases. The book emphasizes clinical advances as proof of concept in cell therapy based on the revolutionizing observation that regeneration can occur throughout the body even in highly differentiated organs like the heart and the neuronal system. It provides examples of breakthroughs in the clinical implementation of adult stem cell therapy.

Cellular therapy. --- Regeneration (Biology). --- Stem cells -- Transplantation. --- Cellular therapy --- Regeneration (Biology) --- Stem cells --- Immunotherapy, Adoptive --- Tissue Engineering --- Regeneration --- Hematopoietic Stem Cell Transplantation --- Stem Cell Transplantation --- Regenerative Medicine --- Adoptive Transfer --- Cell Transplantation --- Medicine --- Biological Processes --- Culture Techniques --- Immunization, Passive --- Biological Phenomena --- Health Occupations --- Transplantation --- Clinical Laboratory Techniques --- Immunization --- Investigative Techniques --- Disciplines and Occupations --- Phenomena and Processes --- Surgical Procedures, Operative --- Immunotherapy --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Immunologic Techniques --- Immunomodulation --- Biological Therapy --- Therapeutics --- Pharmacy, Therapeutics, & Pharmacology --- Oncology --- Health & Biological Sciences --- Transplantation. --- Stem cell transplantation --- Regenerative biology --- Regrowth (Biology) --- Medicine. --- Hematology. --- Oncology. --- Orthopedics. --- Pediatrics. --- Medicine & Public Health. --- Developmental biology --- Autotomy --- Wound healing --- Cell therapy --- Cells --- Therapy, Cellular --- Organotherapy --- Therapeutics, Physiological --- Transplantation of organs, tissues, etc. --- Cell transplantation --- Therapeutic use --- Oncology  . --- Paediatrics --- Pediatric medicine --- Children --- Orthopaedics --- Orthopedia --- Surgery --- Haematology --- Internal medicine --- Blood --- Tumors --- Diseases --- Health and hygiene --- Tissue therapy