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This book describes the bioinformatics research field, from its historical roots to the cutting-edge technologies. Many readers can discover the power of next-generation sequencing and genomic data analysis, uncover the secrets of single-cell genomics and transcriptomics, explore the metagenomics and microbiome analysis, and predict the protein structures using structural bioinformatics. Several case studies witnessing the fusion of bioinformatics and artificial intelligence, driving insights from vast biological datasets have also been explored. Other important aspects listed in the book are integrating the omics data for a holistic view of biological systems; experiencing the future of medicine with precision healthcare and personalized treatments; accelerating drug discovery and repurposing through computational approaches; agricultural genomics; and exploring the role of immunoinformatics in designing effective vaccines against infectious diseases.

Bioinformatics. --- Bioengineering. --- Drug delivery systems. --- Drugs --- Biological and Physical Engineering. --- Computational and Systems Biology. --- Drug Delivery. --- Structure-Based Drug Design. --- Design.

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This book provides readers with an introductory overview of art from the perspective of science, technology, engineering, and mathematics. The author utilizes well-known and important works of art to demonstrate how STEM concepts apply to them. The book’s examples include a structural analysis of Michelangelo’s David. The author covers major breakthroughs in art history, such as the discovery of perspective. The book also discusses other important elements of art, such as color, from a scientific point of view. The author ensures that readers will understand the art terms used by comparing them with terms used in STEM fields of study. In addition, this book: Demonstrates the broad applications for STEM concepts in unexpected fields, such as art history and appreciation Encourages readers to gain an understanding of art that is different from the standard point of view of an art class Includes numerous visual examples help readers to understand how the concepts are applied in a variety of ways About the Author Arthur David Snider, Ph.D., is a Professor Emeritus in the Departments of Mathematics, Physics, and Electrical Engineering at the University of South Florida. He has 50+ years of experience in modeling physical systems in the areas of heat transfer, electromagnetics, microwave circuits, and orbital mechanics, as well as the mathematical areas of numerical analysis, signal processing, differential equations, and optimization.

Art --- Mathematics. --- Arts. --- Architecture --- Bioengineering. --- Optics. --- Art --- Theory of Arts. --- Mathematics in Art and Architecture. --- Biological and Physical Engineering. --- Optics and Photonics. --- Art History. --- Arts. --- Philosophy. --- Mathematics. --- History.

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This book investigates the physical effects of a lightning flash on a person near the down conductor of a lightning protection system. These effects are the touch voltage, the step voltage and the side flash. For this purpose, a full-scale simulation model of the human body with a resistance of 1000 ohms was first created. In the simulation model, the body can touch the down conductor or be placed close to it. Furthermore, the specific resistance of the earth is varied. Likewise, insulating layers such as asphalt can be incorporated into the simulation model. Also, special cases like water permeable layers or water layers on an asphalt layer can be calculated. In post-processing, all relevant values can be determined, such as the energy converted in the body, the charge, the current and the voltage applied to the body. A comparison with the permissible limit values then shows for the lightning protection classes whether there is danger or not and provides information on necessary measures. There is a risk for death and injury if the down conductor is touched. However, there is also a risk of a side flash if a person is standing next to a discharge. Site isolation with dry asphalt is effective, but there is a residual risk of surface discharges. In real situations with wet asphalt, water-permeable layers or asphalt with a water layer, however, there is a great risk of death or injury. Equipotential bonding with an earthing grid is a necessary but not sufficient solution with regard to the induced voltage at negative subsequent stroke. Therefore, the situation must always be examined on a case-by-case basis with regard to the safety requirements. The only effective measure to prevent injury and death due to touch voltage is an insulating down conductor in conjunction with equipotential bonding. The measures for reducing the touch voltage, such as site insulation and equipotential bonding, basically also apply to limiting the step voltage. A risk calculation according to IEC 62305-2 gives the mean time between two events of injury and death MG = 1/RA. The tolerable risk is: RA = 0,0001 or MT = 10.000 years, equivalent to one death in 10.000 years.

Electric power production. --- Bioengineering. --- Natural disasters. --- Electrical Power Engineering. --- Biological and Physical Engineering. --- Natural Hazards. --- Natural calamities --- Disasters --- Biological engineering --- Life science engineering --- Biology --- Engineering --- Synthetic biology --- Electric power generation --- Electricity generation --- Power production, Electric --- Electric power systems --- Electrification

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In this book, we study decision trees for fault diagnosis in circuits and switching networks, which are among the most fundamental models for computing Boolean functions. We consider two main cases: when the scheme (circuit or switching network) has the same mode of operation for both calculation and diagnostics, and when the scheme has two modes of operation—normal for calculation and special for diagnostics. In the former case, we get mostly negative results, including superpolynomial lower bounds on the minimum depth of diagnostic decision trees depending on scheme complexity and the NP-hardness of construction diagnostic decision trees. In the latter case, we describe classes of schemes and types of faults for which decision trees can be effectively used to diagnose schemes, when they are transformed into so-called iteration-free schemes. The tools and results discussed in this book help to understand both the possibilities and challenges of using decision trees to diagnose faults in various schemes. The book is useful to specialists both in the field of theoretical and technical diagnostics. It can also be used for the creation of courses for graduate students.

Automation. --- Engineering mathematics. --- Engineering --- Bioengineering. --- Mathematical and Computational Engineering Applications. --- Biological and Physical Engineering. --- Data processing. --- Biological engineering --- Life science engineering --- Biology --- Synthetic biology --- Engineering analysis --- Mathematical analysis --- Automatic factories --- Automatic production --- Computer control --- Engineering cybernetics --- Factories --- Industrial engineering --- Mechanization --- Assembly-line methods --- Automatic control --- Automatic machinery --- CAD/CAM systems --- Robotics --- Mathematics --- Automation