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Mechanisms of protein folding
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ISBN: 0199637881 019963789X 9780199637881 9780199637898 Year: 2000 Volume: 32 Publisher: Oxford Oxford university press

Protein phosphorylation : the nature, function and metabolism of proteins which contain covalently bound phosphorus
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ISBN: 0850860628 Year: 1979 Publisher: New York (N.Y.): Pion

Protein Nanotechnology : Protocols, Instrumentation, and Applications
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ISBN: 1280359579 9786610359578 1592598587 1588293106 9781588293107 Year: 2005 Publisher: Totowa, NJ : Humana Press : Imprint: Humana,

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Abstract

Rapidly emerging at the intersection of nanotechnology, materials science, and molecular biology, the field of nanobiotechnology promises to elucidate many life processes at the molecular-level previously invisible to human inquiry, and thereby dramatically to transform diagnostics, therapy, and drug discovery in this postgenomic world. In Protein Nanotechnology: Protocols, Instrumentation, and Applications, leading experts in nanobiotechnology comprehensively review the most recent advances in instrumentation and methodology, as well as their applications in genomics and proteomics. The authors provide a wide variety of techniques and methods for dealing with protein functions and structures at the nanoscale level, including nanostructured systems, nanomaterials, carbon nanotubes and nanowires, optical nanosensors, and nanoelectrodes. Among the highlights are techniques for the in vivo tracking of biochemical processes using fluorescent molecular probes and nanosensors, and the exploration of biochemical processes and submicroscopic structures of living cells at unprecedented resolutions using near-field optics. Also discussed is the development of nanocarrier methodology for the targeted delivery of drugs whose shells are conjugated with antibodies for targeting specific antigens. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Protein Nanotechnology: Protocols, Instrumentation, and Applications provides investigators a wide variety of readily reproducible techniques and methods for exploring both protein functions and structures at the nanoscale level and their powerful new biological and medical applications.


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Protein targeting : proceedings of the eight John Innes symposium, Norwich 1988
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ISBN: 0948601213 9780948601217 Year: 1989 Volume: 11


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Introduction to proteins : structure, function, and motion
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ISBN: 9781439810712 1439810710 Year: 2011 Publisher: Boca Raton, FL: CRC,

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"The book aims to provide the reader with a detailed description of protein structure and dynamics, combined with an in-depth discussion of the relationship between both these aspects and protein function. Adopting the structural-biophysical approach, we discuss these in relation to molecular interactions and thermodynamic changes that transpire in this highly complex system. There are several types of textbooks describing protein structure and function. Biochemistry textbooks emphasize the functional aspect of proteins and provide a rather general description of structure and structure-function relationship (SFR). Structural Biology textbooks provide an extensive description of protein structure and also refer to SFR with varying degrees of detail. However, energy-related aspects are often avoided. Molecular biophysics textbooks focus on molecular interactions and thermodynamic aspects of protein structure, but tend to lack detailed description of structural and dynamic aspects, as well as SFR. Our book refers to all of the aforementioned aspects and attempts to provide a unified view. Our energy-oriented approach is manifested throughout the book, whether we discuss structure, dynamics or specific functions of proteins. An extensive discussion of the energetics of protein structure is also given in a chapter dedicated to this topic."--


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Protein function : a practical approach
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ISBN: 0199630062 0199630070 9780199630073 Year: 1990 Publisher: Oxford IRL Press

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Concentrating on the aspects of protein function that are common to the majority of proteins, this collection of methods is brought together for reseachers who are without access to expensive equipment. Using these protocols researchers will be able to get information about the functional properties of any protein. A companion volume, "Protein Structure: A Practical Approach" also edited by Thomas Creighton, provides the methods necessary for the study of protein strucutre.

Computational methods for protein structure prediction and modeling.
Authors: --- ---
ISBN: 0387333193 9780387333199 1441922059 9786611066185 1281066184 0387683720 9780387683720 9781441922069 9780387688251 Year: 2007 Publisher: New York ; London : Springer,

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Abstract

Volume one of this two volume sequence focuses on the basic characterization of known protein structures as well as structure prediction from protein sequence information. The 11 chapters provide an overview of the field, covering key topics in modeling, force fields, classification, computational methods, and struture prediction. Each chapter is a self contained review designed to cover (1) definition of the problem and an historical perspective, (2) mathematical or computational formulation of the problem, (3) computational methods and algorithms, (4) performance results, (5) existing software packages, and (6) strengths, pitfalls, challenges, and future research directions.

Introduction to protein science : architecture, function, and genomics
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ISBN: 0199265119 9780199265114 Year: 2004 Publisher: Oxford Oxford University Press

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This volume provides an introduction to the contempoorary study of proteins. It illustrates the wide range of protein functions and describes how new techniques are helping us to predict a protein's structure and function. It also shows how these techniques have exciting implications in areas such as drug design. (Midwest).

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