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The first review describes examples of very promising compounds discovered from plants acquired from Africa, Southeast Asia, the Americas, and the Caribbean region with potential anticancer activity. These include plant secondary metabolites of the diphyllin lignan, penta[b]benzofuran, triterpenoid, and tropane alkaloid types. The second review presents 40 more erythrinan alkaloids, which were either new or were missed out in the last major reviews, bringing to a total of 154 known erythrinan alkaloids known to date. The reported pharmacological activities of the new and known alkaloids showed a greater bias towards central nervous system and related activities. Other prominent activities reported were antifeedant or insecticidal, cytotoxicity/anti­tumor/anti­cancer/estrogenic, antiprotozoal, antiinflammatory, antioxidant, antifungal and antiviral activities.

Chemistry, Organic. --- Natural products --- Biotechnology. --- Pharmaceutical technology. --- Biochemistry. --- Organic Chemistry. --- Pharmaceutical Sciences/Technology. --- Medicinal Chemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Organic chemistry --- Composition --- Organic chemistry. --- Medicinal chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Pharmaceutical chemistry. --- Pharmaceutics.

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The first contribution summarizes current trends in research on medicinal plants in Mexico with emphasis on work carried out at the authors' laboratories. The most relevant phytochemical and pharmacological profiles of a selected group of plants used widely for treating major national health problems are described. The second contribution provides a detailed survey of the so far reported literature data on the capacities of selected oxyprenylated phenylpropanoids and polyketides to trigger receptors, enzymes, and other types of cellular factors for which they exhibit a high degree of affinity and therefore evoke specifice responses. And the third contribution discusses aspects of endophytic actinobacterial biology and chemistry, including biosynthesis and total synthesis of secondary metabolites produced in culture. It also presents perspectives fo the future of microbial biodiscovery, with emphasis on the seondary metabolism of endophytic actinobacteria.

Chemistry, Organic. --- Pharmaceutical chemistry. --- Clinical biochemistry. --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry --- Pathology --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Organic chemistry --- Pharmaceutical technology. --- Biochemistry. --- Organic Chemistry. --- Pharmaceutical Sciences/Technology. --- Medicinal Chemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Medical sciences --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Composition --- Organic chemistry. --- Medicinal chemistry. --- Pharmaceutics.

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The book summarizes important aspects of cheminformatics that are relevant for natural product research. It highlights cheminformatics tools that help to match natural products with their respective biological targets or off-targets, and discusses the potential and limitations of this approach.

Cheminformatics. --- Chemical informatics --- Chemiinformatics --- Chemoinformatics --- Chemistry informatics --- Chemistry --- Information science --- Data processing --- Organic chemistry. --- Pharmaceutical technology. --- Medicinal chemistry. --- Organic Chemistry. --- Pharmaceutical Sciences/Technology. --- Medicinal Chemistry. --- Organic chemistry --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Pharmaceutical laboratory techniques --- Pharmaceutical laboratory technology --- Technology, Pharmaceutical --- Technology --- Chemistry, Organic. --- Pharmaceutical chemistry. --- Pharmaceutics.

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This volume highlights some recent developments on plants used widely as botanical dietary supplements and herbal medicines, especially in terms of knowledge of the chemical types and diverse biological activities of their constituents, as well as laboratory approaches for their quality control and taxonomic identification. In the first chapter, the biologically active secondary metabolites are described of selected botanicals that have a wide current use in the United States, with recent information provided also on their in vitro and in vivo biological activities. The second chapter constitutes an updated survey of the different chromatographic, spectroscopic, and metabolomics techniques that can be utilized for the quality control of botanical products. The penultimate chapter covers different nomenclatural systems that are of use for the taxonomic identification of source plants used in botanical products. Finally, deoxyribonucleic acid molecular barcoding techniques for the identification for plants used as dietary supplements are covered.

Dietary Supplements. --- Herbal Medicine. --- Plant Extracts. --- Phytochemicals. --- Chemical Phenomena. --- Chemical Phenomenon --- Chemical Process --- Physical Chemistry Phenomena --- Physical Chemistry Process --- Physicochemical Phenomenon --- Physicochemical Process --- Chemical Concepts --- Chemical Processes --- Physical Chemistry Concepts --- Physical Chemistry Processes --- Physicochemical Concepts --- Physicochemical Phenomena --- Physicochemical Processes --- Chemical Concept --- Chemistry Process, Physical --- Chemistry Processes, Physical --- Concept, Chemical --- Concept, Physical Chemistry --- Concept, Physicochemical --- Concepts, Chemical --- Concepts, Physical Chemistry --- Concepts, Physicochemical --- Phenomena, Chemical --- Phenomena, Physical Chemistry --- Phenomena, Physicochemical --- Phenomenon, Chemical --- Phenomenon, Physicochemical --- Physical Chemistry Concept --- Physicochemical Concept --- Process, Chemical --- Process, Physical Chemistry --- Process, Physicochemical --- Processes, Chemical --- Processes, Physical Chemistry --- Processes, Physicochemical --- Bioactive Coumpounds, Plant --- Biologically Active Coumpounds, Plant --- Dietary Phytochemicals --- Phytochemical --- Phytonutrient --- Phytonutrients --- Plant Bioactive Compounds --- Plant Biologically Active Compounds --- Plant-Derived Chemicals --- Plant-Derived Compounds --- Dietary Phytochemical --- Plant Bioactive Compound --- Plant Biologically Active Compound --- Plant-Derived Chemical --- Plant-Derived Compound --- Bioactive Compound, Plant --- Bioactive Compounds, Plant --- Chemical, Plant-Derived --- Chemicals, Plant-Derived --- Compound, Plant Bioactive --- Compound, Plant-Derived --- Compounds, Plant Bioactive --- Compounds, Plant-Derived --- Coumpounds, Plant Bioactive --- Phytochemical, Dietary --- Phytochemicals, Dietary --- Plant Bioactive Coumpounds --- Plant Derived Chemical --- Plant Derived Chemicals --- Plant Derived Compound --- Plant Derived Compounds --- Secondary Metabolism --- Herbal Medicines --- Plant Extract --- Extract, Plant --- Extracts, Plant --- Medicines, Herbal --- Materia Medica --- Phytotherapy --- Plants, Medicinal --- Herbal Medicine --- Hawaiian Herbal Medicine --- La au Lapa au --- La'au Lapa'au --- Laau Lapaau --- Herbalism --- Medicine, Herbal --- Herbal Medicine, Hawaiian --- Medicine, Hawaiian Herbal --- Naturopathy --- Dietary Supplementations --- Food Supplementations --- Herbal Supplements --- Nutraceuticals --- Nutriceuticals --- Food Supplements --- Neutraceuticals --- Dietary Supplement --- Food Supplement --- Herbal Supplement --- Neutraceutical --- Nutraceutical --- Nutriceutical --- Supplement, Food --- Supplement, Herbal --- Supplementations, Dietary --- Supplements, Dietary --- Supplements, Food --- Supplements, Herbal --- Functional Food --- Natural products. --- Biomaterials. --- Nucleic acids. --- Chemical structure. --- Natural Products. --- Nucleic Acid. --- Structure And Bonding. --- Plant Materials. --- Structure, Chemical --- Chemistry, Physical and theoretical --- Matter --- Polynucleotides --- Biomolecules --- Products, Natural --- Raw materials --- Constitution

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The first chapter in volume 111 summarizes research on the sesterterpenoids, which are known as a relatively small group of natural products. However, they express a variety of simple to complicated chemical structures. This chapter focuses on the chemical structures of sesterterpenoids and how their structures are synthesized in Nature. The second chapter is devoted to marine-derived fungi, which play an important role in the search for structurally unique secondary metabolites, some of which show promising pharmacological activities that make them useful leads for drug discovery. Marine natural product research in China in general has made enormous progress in the last two decades as described in this chapter on fungal metabolites. This contribution covers 613 new natural products reported from 2001 to 2017 from marine-derived fungi obtained from algae, sponges, corals, and other marine organisms from Chinese waters.

Organic chemistry --- Pharmacology. Therapy --- Clinical chemistry --- medische chemie --- organische chemie --- farmacologie