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Half-life (Nuclear physics) --- Radioisotopes --- Isotopes radioactifs --- Decay --- Décroissance
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The first step in the development of a framework that allows the comparison of different recommender systems, configurations and ways of implementing them. Additionally, this thesis promotes the sharing of the results of these comparisons and proposes a unified method of representing the comparison.
Clustering. --- Collaborative filtering. --- Coverage. --- Half-life utility. --- Item-based. --- Mean absolute error. --- Pre-processed. --- Program. --- Recommender system. --- User-based.
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Proteins --- Half-Life. --- Protein drugs --- Médicaments protéiques --- Protéines --- pharmacokinetics. --- Design --- Therapeutic use --- Conception --- Emploi en thérapeutique
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621.039.8 --- 539.163 --- Applications of isotopes generally: radioisotopes, stable isotopes --- Radionuclides and their characteristics. Decay schemata. Half-life. Energy spectrum --- 539.163 Radionuclides and their characteristics. Decay schemata. Half-life. Energy spectrum --- 621.039.8 Applications of isotopes generally: radioisotopes, stable isotopes --- Radioisotopes --- Safety measures
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Nuclear physics --- Nuclear physics. --- 33.40 nuclear physics: general --- Atomic nuclei --- Atoms, Nuclei of --- Nucleus of the atom --- Physics --- halfwaardetijd --- half life --- straling --- radiation --- atomen --- atoms --- kernreacties --- nuclear reactions --- Physics (General) --- Fysica (algemeen)
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Nuclear physics --- Radioactive decay --- 539.16 --- Decay, Radioactive --- Radioactive disintegration --- Half-life (Nuclear physics) --- Nuclear reactions --- Radioactivity --- Atomic nuclei --- Atoms, Nuclei of --- Nucleus of the atom --- Physics --- 539.16 Radioactivity. Radioactive decay --- Radioactivity. Radioactive decay
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This paper models empirically the short and long-term behavior of the real exchange rate misalignment-a key variable in academic and policy circles. The equilibrium real exchange rate is derived from a theoretical model with intertemporal external equilibrium and internal equilibrium (in traded and non-traded markets) based on the current account dynamics and Harrod-Balassa-Samuelson productivity, respectively. This provides a bridge between theory and empirics that links the real exchange rate and its fundamentals (terms of trade, the ratio of net foreign assets to gross domestic product, and productivity differentials). The paper contributes to the literature by: (a) estimating an unrestricted vector error correction model that examines the short-term dynamics of real exchange rate misalignments and links these deviations with shocks to fundamentals from 1970 to 2010, and (b) computing the speed of reversion of real exchange rate misalignments with respect to a fundamentals-based equilibrium level. The paper reconciles two strands of the empirical literature that estimate the half-life of purchasing power parity deviations: one, the linear adjustment model that renders the consensus half-life estimates of purchasing power parity deviations, and another, the non-linear adjustment model of purchasing power parity deviations. The model estimates the half-life of real exchange rate deviations from their fundamental equilibrium at approximately 2.8 years. Consequently, about 25 percent of the real exchange rate deviation from its equilibrium level is corrected in the next year. Approximately 43 percent of the countries in the sample have a half-life of real exchange rate deviations from equilibrium less than 2.5 years-which is consistent with predictions from non-linear mean reversion models.
A Half-life --- An Unrestricted VECM --- Currencies and Exchange Rates --- Debt Markets --- Economic Stabilization --- Economic Theory & Research --- Fundamentals --- Macroeconomic Management --- Macroeconomics and Economic Growth --- Misalignment --- Poverty Reduction --- The HBS Effect
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Albumin is playing an increasing role as a versatile, biodegradable drug carrier in clinical theranostics. By applying different techniques, smart drug-delivery systems can be developed from albumin in order to improve drug delivery of different active pharmaceutical ingredients, even small-molecule drugs, peptides or enzymes. Principally, three drug delivery technologies can be distinguished for binding small-molecule or peptide drugs through the charged amino acids, carboxyl, and amino groups of albumin: physical or covalent binding of the drug to albumin through a ligand- or protein-binding group, the fusion of drug with albumin or the encapsulation of drugs into albumin nanoparticles. The accumulation of albumin in inflamed tissues and solid tumours forms the rationale for developing albumin-based drug delivery systems for targeted drug delivery. Besides tumour therapy, albumin-based drug delivery systems can be successfully applied as anti-inflammatory and anti-thrombotic coating for medical devices. The development and optimization of albumin nanoparticles may also be a rational and promising tool for conventional or alternative administration routes in order to improve therapy. This collection provides an overview of the significant scientific research works in this field, which may inspire researchers towards further development and utilization of these smart drug delivery systems.
Medicine. --- plasma half-life extension --- albumin conjugation --- in vivo glucose-lowering activity --- glucagon-like peptide-1 --- quality by design --- rapid equilibrium dialysis --- muco-adhesion --- brain PAMPA --- RPMI 2650 nasal epithelial cell --- human serum albumin --- dimerization --- doxorubicin --- enhanced permeability and retention effect --- antitumor --- Arthrobacter globiformis --- gout --- half-life extension --- inverse electron demand Diels-Alder reaction --- site-specific albumin conjugation --- thermostability --- urate oxidase --- albumin --- anti-thrombotic --- CD39 --- coating of medical devices --- stent coating --- therapeutic fusion protein --- conjugates --- vanadium --- cancer --- prodrug --- hydrogels --- EPR/ESR spectroscopy --- release behavior --- disulfide --- glioma --- conjugate --- albumin binding moieties --- peptides --- Evans blue --- 4-(p-iodophenyl)butyric acid --- integrin αvβ6 --- integrin αvβ6 binding peptide --- improved pharmacokinetics --- PET imaging
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Albumin is playing an increasing role as a versatile, biodegradable drug carrier in clinical theranostics. By applying different techniques, smart drug-delivery systems can be developed from albumin in order to improve drug delivery of different active pharmaceutical ingredients, even small-molecule drugs, peptides or enzymes. Principally, three drug delivery technologies can be distinguished for binding small-molecule or peptide drugs through the charged amino acids, carboxyl, and amino groups of albumin: physical or covalent binding of the drug to albumin through a ligand- or protein-binding group, the fusion of drug with albumin or the encapsulation of drugs into albumin nanoparticles. The accumulation of albumin in inflamed tissues and solid tumours forms the rationale for developing albumin-based drug delivery systems for targeted drug delivery. Besides tumour therapy, albumin-based drug delivery systems can be successfully applied as anti-inflammatory and anti-thrombotic coating for medical devices. The development and optimization of albumin nanoparticles may also be a rational and promising tool for conventional or alternative administration routes in order to improve therapy. This collection provides an overview of the significant scientific research works in this field, which may inspire researchers towards further development and utilization of these smart drug delivery systems.
Medicine. --- plasma half-life extension --- albumin conjugation --- in vivo glucose-lowering activity --- glucagon-like peptide-1 --- quality by design --- rapid equilibrium dialysis --- muco-adhesion --- brain PAMPA --- RPMI 2650 nasal epithelial cell --- human serum albumin --- dimerization --- doxorubicin --- enhanced permeability and retention effect --- antitumor --- Arthrobacter globiformis --- gout --- half-life extension --- inverse electron demand Diels-Alder reaction --- site-specific albumin conjugation --- thermostability --- urate oxidase --- albumin --- anti-thrombotic --- CD39 --- coating of medical devices --- stent coating --- therapeutic fusion protein --- conjugates --- vanadium --- cancer --- prodrug --- hydrogels --- EPR/ESR spectroscopy --- release behavior --- disulfide --- glioma --- conjugate --- albumin binding moieties --- peptides --- Evans blue --- 4-(p-iodophenyl)butyric acid --- integrin αvβ6 --- integrin αvβ6 binding peptide --- improved pharmacokinetics --- PET imaging
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Nowadays experimental nuclear physics pushes its limits towards highly unstable nuclei. The theoretical description of proton-rich and neutronrich nuclei or superheavy elements has become an important part of the modern nuclear physics. The main tool to investigate such unstable nuclei concerns radioactive decays, from proton emission to fission processes. We review the main theoretical methods describing decay processes induced by the strong interaction, like Coupled channels method for Gamow resonances, R-matrix theory, Distorted wave approach, Semiclassical approach, Multi step and Two center shell model. Thus, most of the book is addressed to a broad audience within the nuclear physics community. Secondly, this book is an attempt to clarify some fundamental aspects connected with the fine structure or anisotropy in alpha decay and ternary cold fission. Finally, the self consistent microscopic theory of the alpha decay is analyzed.
Radioactive decay --- Physics --- Physical Sciences & Mathematics --- Electricity & Magnetism --- Nuclear Physics --- Photon emission. --- Radioactive decay. --- Decay, Radioactive --- Radioactive disintegration --- Emission of photons --- Photon bremsstrahlung --- Photon radiation --- Photons --- Radiation, Photon --- Emission --- Physics. --- Nuclear physics. --- Heavy ions. --- Hadrons. --- Nuclear Physics, Heavy Ions, Hadrons. --- Half-life (Nuclear physics) --- Nuclear reactions --- Radioactivity --- Bremsstrahlung --- Atomic nuclei --- Atoms, Nuclei of --- Nucleus of the atom --- Ions
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