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DNA-protein interactions --- DNA-protein interactions.

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DNA-protein interactions --- Research --- Methodology

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Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. Covers reviews of methodology and research in all as

Proteins. --- Nucleic acids. --- DNA-protein interactions.

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Transcription factors --- DNA-protein interactions --- Genetic regulation --- Congresses.

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The pivotal role played by transcription factors in regulating gene expression has ensured that their study is a major area of current research activity. This book provides a comprehensive description of all the approaches and methods required to identify, isolate and characterize transcription factors. Starting with a specific DNA sequence, these protocols allow the detection and identification of proteins that bind to it and detailed analysis of the DNA binding site. This is followed by procedures for the functional assay of transcription factors and their purification. Also included are methods for the characterization of transcription factor genes, including DNA cloning. The analysis of transcription factors is of central interest to all molecular biologists involved in studying gene expression, making this book an important text for a wide range of researchers from postgraduate students to established scientists.

Transcription Factors --- DNA-protein interactions --- Genetic regulation --- Transcription factors --- Régulation génétique --- Facteurs de transcription --- physiology --- DNA-protein interactions. --- Genetic regulation. --- Transcription factors. --- physiology. --- Régulation génétique