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This book was written by many outstanding investigators who have spent decades to study different aspects of blood‑tissue barrier function. They have summarized some of the latest and fascinating development in their fields of research including the blood‑brain barrier, the blood‑retinal barrier, the gut barrier, the blood‑biliary barrier, the blood‑follicle barrier, the blood‑epididymis barrier, the blood‑testis barrier, the tight junction barrier in general as well as barriers in the female reproductive tract. Included are also chapters that focus on topics that are physiologically applicable to all blood‑tissue barriers. Many of these chapters also include information on specific human diseases, such as pathological changes of the gut barrier that cause bowel disorders resulting from inflammation of the epithelial lining in the intestine, and infertility in men as a result of disruption of the blood‑epididymal and/or blood‑testis barriers; and on new therapeutic approaches (e.g., drug delivery across the blood‑brain and the blood‑retinal barriers).

Blood-air barrier. --- Blood-brain barrier. --- Capillaries -- Permeability. --- Capillary permeability. --- Blood-brain barrier --- Capillaries --- Cardiovascular Physiological Phenomena --- Retina --- Seminiferous Tubules --- Pulmonary Alveoli --- Cardiovascular System --- Biological Transport --- Brain --- Anatomy --- Testis --- Central Nervous System --- Lung --- Eye --- Circulatory and Respiratory Physiological Phenomena --- Metabolism --- Respiratory System --- Sense Organs --- Metabolic Phenomena --- Phenomena and Processes --- Nervous System --- Genitalia, Male --- Genitalia --- Urogenital System --- Blood-Air Barrier --- Blood-Brain Barrier --- Blood-Testis Barrier --- Capillary Permeability --- Blood-Retinal Barrier --- Human Anatomy & Physiology --- Health & Biological Sciences --- Neuroscience --- Permeability --- Permeability. --- Blood-cerebral barrier --- Blood-cerebrospinal fluid barrier --- Brain-blood barrier --- Hemato-encephalic barrier --- Hematoencephalic barrier --- Medicine. --- Molecular biology. --- Biomedicine. --- Molecular Medicine. --- Biomedicine general. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Cerebrospinal fluid --- Choroid plexus --- Blood-vessels --- Biomedicine, general. --- Health Workforce

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• Reference Manager
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This book was written by many outstanding investigators who have spent decades to study different aspects of blood‑tissue barrier function. They have summarized some of the latest and fascinating development in their fields of research including the blood‑brain barrier, the blood‑retinal barrier, the gut barrier, the blood‑biliary barrier, the blood‑follicle barrier, the blood‑epididymis barrier, the blood‑testis barrier, the tight junction barrier in general as well as barriers in the female reproductive tract. Included are also chapters that focus on topics that are physiologically applicable to all blood‑tissue barriers. Many of these chapters also include information on specific human diseases, such as pathological changes of the gut barrier that cause bowel disorders resulting from inflammation of the epithelial lining in the intestine, and infertility in men as a result of disruption of the blood‑epididymal and/or blood‑testis barriers; and on new therapeutic approaches (e.g., drug delivery across the blood‑brain and the blood‑retinal barriers).

Molecular biology --- Human biochemistry --- Pathological biochemistry --- Human medicine --- medische biochemie --- biochemie --- biomedische wetenschappen --- moleculaire biologie

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In the past thirty years, significant advances have been made in the field of reproductive biology in unlocking the molecular and biochemical events that regulate spermatogenesis in the mammalian testis. It was possible because of the unprecedented breakthroughs in molecular biology, cell biology, immunology, and biochemistry. In this book entitled, Molecular Mechanisms in Spermatogenesis, a collection of chapters has been included written by colleagues on the latest development in the field using genomic and proteomic approaches to study spermatogenesis, as well as different mechanisms and/or molecules including environmental toxicants and transcription factors that regulate and/or affect spermatogenesis. The book begins with a chapter that provides the basic concept of cellular regulation of spermatogenesis. A few chapters are also dedicated to some of the latest findings on the Sertoli cell cytoskeleton and other molecules (e.g., proteases, adhesion proteins) that regulate spermatogenesis. These chapters contain thought-provoking discussions and concepts which shall be welcomed by investigators in the field. It is obvious that many of these concepts will be updated and some may be amended in the years to come. However, they will serve as a guide and the basis for investigation by scientists in the field.

Molecular biology --- Human biochemistry --- medische biochemie --- biochemie --- moleculaire biologie