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L’exposition professionnelle aux animaux de laboratoire (rats, souris) peut, chez certains sujets, provoquer une réaction inflammatoire au niveau des voies respiratoires. Au cours de cette étude, qui a comporté un premier temps transversal, et un second, longitudinal, nous avons évalué un outil potentiel pour détecter cette atteinte inflammatoire à un stade précoce. La méthode du lavage nasal a été pratiquée parmi dix volontaires travaillant dans un laboratoire de recherche. Cinq d’entre eux étaient régulièrement exposés aux animaux de laboratoire (rats, souris), cinq ne l’étaient pas. Excepté un sujet absent lors de la dernière séance, chaque volontaire a subi quatre lavages des fosses nasales répartis sur une période de trois mois, de décembre 1996 à février 1997. L’analyse des liquides de lavage ainsi recueillis s’est basée, d’une part, sur l’étude cellulaire réalisée à partir du culot, et, d’autre par , sur les dosages de médiateurs de l’inflammation (protéines totales, albumine, interleukines 8 et 10, protéine CC-16). Avant chaque lavage, nous avons noté les principaux facteurs pouvant influencer le statut inflammatoire de la muqueuse respiratoire supérieure, tels le recours récent à des médicaments locaux ou généraux, les maladies et infections respiratoires hautes proches de chaque lavage, une exposition récente à des irritants respiratoires ainsi que le tabagisme. L’étude cellulaire s’est révélée peu contributive et e montré d’importantes variabilités inter- et intra-individuelles. L’analyse des médiateurs inflammatoires a révélée que ceux-ci sont davantage influencés par une infection respiratoire haute marquée ou par le tabagisme que par l’exposition aux animaux de laboratoire. L’hétérogénéité de la population étudiée, telle qu’on peut la rencontrer dans les milieux professionnels d’une part, rendent difficiles l’interprétation des résultats et donc le recours à ce type d’examen lors du suivi périodique de travailleurs exposés professionnellement à des irritants et/ou allergisants respiratoires.
Therapeutic Irrigation --- Respiratory Tract Infections --- Occupational Exposure
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Therapeutic Irrigation --- Anti-Bacterial Agents --- Colon --- Premedication --- therapeutic use --- surgery
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Colonic Diseases --- Rectal Diseases --- Anti-Bacterial Agents --- Therapeutic Irrigation --- surgery --- surgery
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Psychic trauma --- Post-traumatic stress disorder --- Stress (Psychology) --- Psychotherapy --- Psychoanalytic Therapy. --- Stress Disorders, Post-Traumatic --- Stress, Psychological. --- Psychotherapy. --- Treatment --- therapy. --- Treatment. --- Psychagogy --- Therapy (Psychotherapy) --- Psychological Stress --- Stress, Psychologic --- Suffering --- Anguish --- Emotional Stress --- Life Stress --- Mental Suffering --- Life Stresses --- Psychologic Stress --- Psychological Stresses --- Stress, Emotional --- Stress, Life --- Stresses, Life --- Stresses, Psychological --- Suffering, Mental --- Psychoanalytic Therapy, Balint --- Psychoanalytical Therapy --- Therapy, Balint Psychoanalytic --- Therapy, Psychoanalytic --- Balint Psychoanalytic Therapy --- Psychoanalytic Therapies --- Psychoanalytical Therapies --- Therapies, Psychoanalytic --- Therapies, Psychoanalytical --- Therapy, Psychoanalytical --- Emotional stress --- Mental stress --- Psychological stress --- Tension (Psychology) --- Posttraumatic stress disorder --- PTSD (Psychiatry) --- Stress disorder, Post-traumatic --- Traumatic stress syndrome --- Emotional trauma --- Injuries, Psychic --- Psychic injuries --- Trauma, Emotional --- Trauma, Psychic --- Mental illness --- Clinical sociology --- Mental health counseling --- Mental health --- Psychology --- Diathesis-stress model (Psychology) --- Life change events --- Type A behavior --- Anxiety disorders --- Traumatic neuroses --- Intrusive thoughts --- Psychology, Pathological --- Stressor, Psychological --- Psychological Stressor --- Psychological Stressors --- Stressors, Psychological --- Sufferings --- therapeutics. --- psychological stress. --- emotional stress --- mental stress --- worry --- pathological processes and conditions --- psychology --- distress --- occupational stress --- family problems --- life events --- mental health --- stress management --- therapeutic effect --- therapy --- Health and Pathology --- alternative medicine --- analgesia --- anesthesia --- anti-HIV therapy --- blood transfusion --- cancer therapy --- cardiopulmonary resuscitation --- chemosensitization --- contraception --- diet therapy --- dosage --- drug delivery systems --- drug therapy --- first aid --- fluid therapy --- gene therapy --- group therapy --- hemodialysis --- immunotherapy --- lithotripsy --- magnetic therapy --- massage --- medical treatment --- occupational therapy --- phage therapy --- physical therapy --- phytotherapy --- plasmapheresis --- precision medicine --- psychotherapy --- radiotherapy --- rehabilitation (people) --- sedation --- surgery --- therapeutic irrigation --- thermotherapy --- topical therapy --- wound treatment --- adverse effects --- control methods --- dose response --- medicine --- veterinary medicine --- Psychoanalytic Therapy --- Stress, Psychological
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Arrhythmia --- Cardiac pacing --- Catheter ablation --- Heart --- Electrophysiology --- Arrhythmias, Cardiac --- Cardiac Pacing, Artificial. --- Catheter Ablation. --- Electrophysiology. --- Arythmie --- Cœur --- Électrophysiologie --- Cardiac pacing. --- Catheter ablation. --- Treatment --- Physiology --- therapy. --- physiology. --- Traitement --- Stimulation --- Physiologie --- Propriétés électriques --- Treatment. --- Physiology. --- Animal electricity --- Bioelectricity --- Electricity, Animal --- Electrobiology --- Ablation, Catheter --- Electric catheter ablation --- Percutaneous catheter ablation --- Radiofrequency catheter ablation --- Transvenous catheter ablation --- Artificial cardiac pacing --- Cardiac pacing, Artificial --- Heart pacing --- Pacing, Cardiac --- Ablation, Transvenous Electrical --- Catheter Ablation, Electrical --- Electric Catheter Ablation --- Electrical Catheter Ablation --- Percutaneous Catheter Ablation --- Radiofrequency Catheter Ablation --- Transvenous Catheter Ablation --- Ablation, Transvenous Electric --- Catheter Ablation, Electric --- Catheter Ablation, Percutaneous --- Catheter Ablation, Radiofrequency --- Catheter Ablation, Transvenous --- Ablation, Electric Catheter --- Ablation, Electrical Catheter --- Ablation, Percutaneous Catheter --- Ablation, Radiofrequency Catheter --- Ablation, Transvenous Catheter --- Electric Ablation, Transvenous --- Electrical Ablation, Transvenous --- Transvenous Electric Ablation --- Transvenous Electrical Ablation --- Pacing, Cardiac, Artificial --- Artificial Cardiac Pacing --- Artificial Cardiac Pacings --- Cardiac Pacings, Artificial --- Pacing, Artificial Cardiac --- Pacings, Artificial Cardiac --- Allorhythmia --- Arhythmia --- Arrhythmias --- Cardiac arrhythmia --- Dysrhythmia --- Irregular heart beats --- Cardiac Pacing, Artificial --- Catheter Ablation --- therapy --- physiology --- Hearts --- Arrythmia --- Cardiac Arrhythmia --- Cardiac Arrhythmias --- Cardiac Dysrhythmia --- Arrhythmia, Cardiac --- Dysrhythmia, Cardiac --- Neurology --- Electricity --- Catheterization --- Electrosurgery --- Electric stimulation --- Cardiopulmonary system --- Cardiovascular system --- Chest --- Heart beat --- Electric countershock --- Palpitation --- Angioplasty, Laser --- Electric Stimulation --- Heart Conduction System --- Physiological effect --- Diseases --- Électrophysiologie --- Propriétés électriques --- Health Sciences --- Life Sciences --- Cardiology --- Clinical Medicine --- Cytology, Cell Biology --- General and Others --- therapeutics. --- electrophysiology. --- heart. --- Biological Sciences --- animal physiology --- body composition --- ecophysiology --- electrophysiology --- excretion --- exudation --- fungus physiology --- growth and development --- metabolism --- microbial physiology --- nutrient use efficiency --- nutrition physiology --- ocular physiology --- oxygen requirement --- peak oxygen uptake --- physiological regulation --- physiological response --- physiological state --- physiological transport --- plant physiology --- psychophysiology --- reproduction --- secretion --- somatic incompatibility --- taxis (physiology) --- tissue distribution --- tropisms --- water requirement --- biochemistry --- pathophysiology --- physiologists --- endocardium --- animal organs --- cardiovascular system --- heart atrium --- heart valves --- heart ventricle --- myocardium --- cardioprotective effect --- electrocardiography --- heart health --- heart transplant --- bioelectrical impedance --- bioelectricity --- evoked potentials --- membrane potential --- therapeutic effect --- Health and Pathology --- alternative medicine --- analgesia --- anesthesia --- anti-HIV therapy --- blood transfusion --- cancer therapy --- cardiopulmonary resuscitation --- chemosensitization --- contraception --- diet therapy --- dosage --- drug delivery systems --- drug therapy --- first aid --- fluid therapy --- gene therapy --- group therapy --- hemodialysis --- immunotherapy --- lithotripsy --- magnetic therapy --- massage --- medical treatment --- occupational therapy --- phage therapy --- physical therapy --- phytotherapy --- plasmapheresis --- precision medicine --- psychotherapy --- radiotherapy --- rehabilitation (people) --- sedation --- surgery --- therapeutic irrigation --- thermotherapy --- topical therapy --- wound treatment --- adverse effects --- control methods --- dose response --- medicine --- veterinary medicine --- Ablation percutanée --- Ablation percutanée. --- Électrophysiologie. --- Electric properties --- Electric properties. --- Electrocardiography
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