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Ion Channels

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Ion transporters are membrane proteins that allow the passage of ions or charged small molecules through the lipid membrane. They are present in every cell of every organism. The group of ion transporters comprises different types of ion pumps, ion exchangers, and ion channels. This book focuses mostly on ion channels, which represent the biggest subset of ion transporters. Ion transporters, especially ion channels, are of imminent interest in the field of life sciences with possible therapeutic outcomes. Each piece of knowledge that can help us understand their role and function is worth noticing. This book provides a comprehensive overview of ion channels, including their diversity and functions in physiology and pathophysiology.

Ion channels.

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Ion channels

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• Reference Manager
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Ion transporters are membrane proteins that allow the passage of ions or charged small molecules through the lipid membrane. They are present in every cell of every organism. The group of ion transporters comprises different types of ion pumps, ion exchangers, and ion channels. This book focuses mostly on ion channels, which represent the biggest subset of ion transporters. Ion transporters, especially ion channels, are of imminent interest in the field of life sciences with possible therapeutic outcomes. Each piece of knowledge that can help us understand their role and function is worth noticing. This book provides a comprehensive overview of ion channels, including their diversity and functions in physiology and pathophysiology.

Ion channels.

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This dissertation by Malin Silverå Ejneby explores the impact of resin acids on voltage-gated ion channels, which are essential for electrical signaling in the heart and brain. The study investigates the binding site and mechanism of action of resin acids, revealing that these compounds bind in a unique site between the lipid bilayer and the Shaker Kv channel's voltage-sensor domain. The research aims to enhance the understanding of resin acids as potential drug candidates for conditions like epilepsy and cardiac arrhythmia by improving their efficacy and selectivity. The work involves various methodologies, including chemical synthesis, mathematical modeling, and computer simulations, to test over 140 resin acid derivatives. The intended audience includes researchers and professionals in pharmacology and medical sciences.

Ion channels. --- Pharmacology. --- Ion channels --- Pharmacology